Integrating genome- and transcriptome-wide association studies to uncover the host-microbiome interactions in bovine rumen methanogenesis [0.03%]
整合基因组和转录组的全基因组关联分析以揭示反刍动物瘤胃产甲烷过程中宿主与微生物之间的互作关系
Wei Wang,Zhenyu Wei,Zhuohui Li et al.
Wei Wang et al.
The ruminal microbiota generates biogenic methane in ruminants. However, the role of host genetics in modifying ruminal microbiota-mediated methane emissions remains mysterious, which has severely hindered the emission control of this notor...
ImageGP 2 for enhanced data visualization and reproducible analysis in biomedical research [0.03%]
ImageGP 2：生物医学研究中增强的数据可视化和可重复分析工具
Tong Chen,Yong-Xin Liu,Tao Chen et al.
Tong Chen et al.
ImageGP is an extensively utilized, open-access platform for online data visualization and analysis. Over the past 7 years, it has catered to more than 700,000 usages globally, garnering substantial user feedback. The updated version, Image...
OmicShare tools: A zero-code interactive online platform for biological data analysis and visualization [0.03%]
OmicShare在线工具集：一款无需编程实现组学数据挖掘和可视化的在线平台
Hongyan Mu,Jianzhou Chen,Wenjie Huang et al.
Hongyan Mu et al.
The OmicShare tools platform is a user-friendly online resource for data analysis and visualization, encompassing 161 bioinformatic tools. Users can easily track the progress of projects in real-time through an overview interface. The platf...
Novel microbial modifications of bile acids and their functional implications [0.03%]
新型肠道微生物胆汁酸修饰反应及其功能意义
Dan Zheng,Huiheng Zhang,Xiaojiao Zheng et al.
Dan Zheng et al.
This review outlines the recent discoveries of bile acids that have undergone novel microbial modifications, highlighting their biological roles and the profound implications for the development of innovative therapeutic strategies. The rev...
Efficient and easy-to-use capturing three-dimensional metagenome interactions with GutHi-C [0.03%]
一种高效简便的三维肠道元基因组相互作用捕获方法GutHi-C
Yu-Xi Lu,Jin-Bao Yang,Chen-Ying Li et al.
Yu-Xi Lu et al.
Hi-C can obtain three-dimensional chromatin structure information and is widely used for genome assembly. We constructed the GutHi-C technology. As shown in the graphical abstract, it is a highly efficient and quick-to-operate method and ca...
Dietary therapies interlinking with gut microbes toward human health: Past, present, and future [0.03%]
膳食疗法与肠道微生特群联合促进人类健康：过去、现在和未来
Jiali Chen,Jiaqiang Luo,Sjaak Pouwels et al.
Jiali Chen et al.
Overview of personalized dietary therapies. This flow chart exhibits the future prospect for integrating human microbiome and bio-medical research to revolutionize the precise personalized dietary therapies. With the development of artifici...
LTBR acts as a novel immune checkpoint of tumor-associated macrophages for cancer immunotherapy [0.03%]
LTBR作为肿瘤相关巨噬细胞的新型免疫检查点在癌症免疫治疗中的作用
Liang Wang,Jieyi Fan,Sifan Wu et al.
Liang Wang et al.
Tumor-associated macrophages (TAMs) greatly contribute to immune checkpoint inhibitor (ICI) resistance of cancer. However, its underlying mechanisms and whether TAMs can be promising targets to overcome ICI resistance remain to be unveiled....
The rheumatoid arthritis gut microbial biobank reveals core microbial species that associate and effect on host inflammation and autoimmune responses [0.03%]
类风湿关节炎肠道微生物生物库揭示了与宿主炎症和自身免疫反应相关并影响宿主炎症和自身免疫反应的核心微生物种类
Hao-Jie Huang,Chang Liu,Xin-Wei Sun et al.
Hao-Jie Huang et al.
Gut microbiota dysbiosis has been implicated in rheumatoid arthritis (RA) and influences disease progression. Although molecular and culture-independent studies revealed RA patients harbored a core microbiome and had characteristic bacteria...
USEARCH 12: Open-source software for sequencing analysis in bioinformatics and microbiome [0.03%]
USEARCH 12：生物信息学和微生物组测序分析的开源软件
Yuanping Zhou,Yong-Xin Liu,Xuemeng Li
Yuanping Zhou
The well-known bioinformatic software USEARCH v12 was open sourced. Its meaning encourages the microbiome research community to constantly develop excellent bioinformatic software based on the codes. The open source and popularization of ar...
Multi-level insights into the immuno-oncology-microbiome axis: From biotechnology to novel therapies [0.03%]
免疫肿瘤微生物组轴的多层次见解：从生物技术到新型疗法
Zheshun Pi,Weici Liu,Chenghu Song et al.
Zheshun Pi et al.
The multifaceted interactions among the immune system, cancer cells and microbial components have established a novel concept of the immuno-oncology-microbiome (IOM) axis. Microbiome sequencing technologies have played a pivotal role in not...