The unstable evolutionary position of Korarchaeota and its relationship with other TACK and Asgard archaea [0.03%]
Korarchaeota在进化树上的不稳定位置及其与其他TACK和Asgard古菌的关系
Yang Liu,Meng Li
Yang Liu
The applications of marker gene concatenation have been advanced to resolve the key questions in the Tree of Life. However, the interphylum evolutionary relationship between Korarchaeota of TACK (Thaumarchaeota, Aigarchaeota, Crenarchaeota,...
(S)-3-aminopiperidine-2,6-dione is a biosynthetic intermediate of microbial blue pigment indigoidine [0.03%]
(S)-3-氨基哌啶-2,6-二酮是微生物蓝色色素吲哚青素的生物合成中间体
Zhilong Zhang,Pengwei Li,Min Wang et al.
Zhilong Zhang et al.
The biosynthetic investigations of microbial natural products continuously provide powerful biocatalysts for the preparation of valuable chemicals. Practical methods for preparing (S)-3-aminopiperidine-2,6-dione (2), the pharmacophore of th...
Bacillus subtilis produces (p)ppGpp in response to the bacteriostatic antibiotic chloramphenicol to prevent its potential bactericidal effect [0.03%]
枯草芽孢杆菌通过产生(pp)Gpp响应抑菌抗生素氯霉素以防止其潜在的杀菌效应
Jin Yang,Jessica T Barra,Danny K Fung et al.
Jin Yang et al.
Antibiotics combat bacteria through their bacteriostatic (by growth inhibition) or bactericidal (by killing bacteria) action. Mechanistically, it has been proposed that bactericidal antibiotics trigger cellular damage, while bacteriostatic ...
Fatty acid feedstocks enable a highly efficient glyoxylate-TCA cycle for high-yield production of β-alanine [0.03%]
脂肪酸原料使甘氧酸-三羧酸循环高效运转以高产生成脎氨酸
Yingchun Miao,Jiao Liu,Xuanlin Wang et al.
Yingchun Miao et al.
Metabolic engineering to produce tricarboxylic acid (TCA) cycle-derived chemicals is usually associated with problems of low production yield and impaired cellular metabolism. In this work, we found that fatty acid (FA) feedstocks could ena...
The monkey microbial biobank brings previously uncultivated bioresources for nonhuman primate and human gut microbiomes [0.03%]
猴类微生物菌种保藏库为非人灵长类和人类肠道微生物组提供此前无法培养的生物资源
Danhua Li,Chang Liu,Rexiding Abuduaini et al.
Danhua Li et al.
Nonhuman primates (NHPs) such as monkeys are the closest living relatives to humans and are the best available models for causative studies of human health and diseases. Gut microbiomes are intensively involved in host health. In this study...
A bacterial symbiont in the gill of the marine scallop Argopecten irradians irradians metabolizes dimethylsulfoniopropionate [0.03%]
海湾扇贝(Argopecten irradians irradians)鳃部细菌共生体代谢二甲基硫代丙酸内酯
Yi Shu,Yongming Wang,Zhongcheng Wei et al.
Yi Shu et al.
Microbial lysis of dimethylsulfoniopropionate (DMSP) is a key step in marine organic sulfur cycling and has been recently demonstrated to play an important role in mediating interactions between bacteria, algae, and zooplankton. To date, mi...
The secretory Candida effector Sce1 licenses fungal virulence by masking the immunogenic β-1,3-glucan and promoting apoptosis of the host cells [0.03%]
分泌型假丝酵母效应因子Sce1通过掩盖免疫原性β-1,3-糖复合物并促进宿主细胞凋亡来赋予真菌致病性
Hongyu Wu,Li Wang,Wenjuan Wang et al.
Hongyu Wu et al.
Candida albicans deploys a variety of mechanisms such as morphological switch and elicitor release to promote virulence. However, the intricate interactions between the fungus and the host remain poorly understood, and a comprehensive inven...
Spatial scaling of soil microbial co-occurrence networks in a fragmented landscape [0.03%]
片段景观下土壤微生物共发生网络的空间尺度效应研究
Pandeng Wang,Shao-Peng Li,Xian Yang et al.
Pandeng Wang et al.
Habitat loss has been a primary threat to biodiversity. However, species do not function in isolation but often associate with each other and form complex networks. Thus, revealing how the network complexity and stability scale with habitat...
Single-cell Raman and functional gene analyses reveal microbial P solubilization in agriculture waste-modified soils [0.03%]
单细胞拉曼及功能基因分析揭示农业废弃物改良土壤的微生物解磷作用
Hongzhe Li,Jiazhi Ding,Longji Zhu et al.
Hongzhe Li et al.
Application of agricultural waste such as rapeseed meal (RM) is regarded as a sustainable way to improve soil phosphorus (P) availability by direct nutrient supply and stimulation of native phosphate-solubilizing microorganisms (PSMs) in so...
A host E3 ubiquitin ligase regulates Salmonella virulence by targeting an SPI-2 effector involved in SIF biogenesis [0.03%]
一个宿主E3泛素连接酶通过靶向一个参与SIF形成的SPI-2效应物来调节沙门氏菌的致病性
Kun Meng,Jin Yang,Juan Xue et al.
Kun Meng et al.
Salmonella Typhimurium creates an intracellular niche for its replication by utilizing a large cohort of effectors, including several that function to interfere with host ubiquitin signaling. Although the mechanism of action of many such ef...