Wei Qian,Jizhong Zhou
Wei Qian
Editorial
mLife. 2026 Feb 23;5(1):1-2. DOI:10.1002/mlf2.70074 2026
Salinization influences the biodiversity-ecosystem functioning relationship more strongly at high salinity [0.03%]
在高盐度条件下，盐化作用对生物多样性生态系统功能关系的影响更强烈
Jianrong Huang,Mingxian Han,Jian Yang et al.
Jianrong Huang et al.
Salinization threatens ecosystem stability by altering microbial diversity and function, yet how salinity influences biodiversity-ecosystem functioning (BEF) relationships remains unclear. In this study, we constructed artificial microbial ...
ZapA uses a two-pronged mechanism to facilitate Z ring formation in Escherichia coli [0.03%]
ZapA采用双重机制促进大肠杆菌中Z环的形成
Yuanyuan Cui,Han Gong,Di Yan et al.
Yuanyuan Cui et al.
The tubulin-like protein FtsZ assembles into the Z ring that leads to the assembly and activation of the division machinery in most bacteria. ZapA, a widely conserved protein that interacts with FtsZ, plays a pivotal role in organizing FtsZ...
Dual glycosylation of wall teichoic acid modulates the O-antigen pattern and virulence in serovar 4b Listeria monocytogenes [0.03%]
双糖基化对溶血性李斯特菌的O-抗原模式和毒力的调节作用研究
Hao Yao,Yuting Wang,Ruochen Wang et al.
Hao Yao et al.
Among the 14 serovars of Listeria monocytogenes (Lm), serovar 4b strains are the most predominant isolates linked to human listeriosis outbreaks-a phenotype associated with their unique wall teichoic acid (WTA) decorated with galactose (Gal...
Modulation of host cell pathways by Coxiella burnetii Dot/Icm effectors [0.03%]
柯克斯体的Dot/Icm效应物对宿主细胞途径的调节作用
Jingya Yuan,Yong Zhang,Lei Song et al.
Jingya Yuan et al.
Coxiella burnetii, the etiological agent of Q fever, is a significant intracellular bacterial pathogen. C. burnetii is a highly infectious pathogen that primarily targets pulmonary alveolar macrophages during natural infection. It can then ...
RNA editing system: Balancing altruistic antiviral defense and fitness trade-offs in fungi [0.03%]
RNA编辑系统：在真菌中平衡利他的抗病毒防御和适应性权衡
Yanfei Du,Daohong Jiang,Huiquan Liu
Yanfei Du
CcpA promotes Staphylococcus aureus virulence by directly controlling staphyloxanthin production [0.03%]
CCpA通过直接控制金黄色葡萄球菌的藤黄素产生来促进其毒力
Xian Chen,Huagang Peng,Xiancai Rao et al.
Xian Chen et al.
Staphylococcus aureus is a notorious opportunistic pathogen with remarkable adaptability, enabling it to infect virtually every human tissue. Staphyloxanthin (STX), a critical virulence factor, contributes to S. aureus oxidative damage. How...
Cis-2-decenoic acid modulates Pseudomonas aeruginosa virulence through a noncanonical transcriptional regulator [0.03%]
反式-2-癸烯酸通过非经典的转录调节因子调节铜绿假单胞菌的致病性
Shihao Song,Jingyun Liu,Bing Wang et al.
Shihao Song et al.
Diffusible signal factor (DSF)-family quorum sensing (QS) signals are widely utilized by many pathogenic bacteria to modulate various biological functions and virulence. Previous studies showed that cis-2-decenoic acid (cis-DA) is involved ...
Engineered AcrIIA5 for optogenetic control of CRISPR-Cas9-based genome editing [0.03%]
用于CRISPR-Cas9基因编辑的光遗传调控工程化AcR II A5
Qi Chen,Jia Yao,Yingfan Lu et al.
Qi Chen et al.
The CRISPR-Cas9 system has been proven to be a powerful tool for gene editing in living cells and shows great potential in genetic disease treatment. Anti-CRISPR (Acr)-based optogenetic tools could spatiotemporally regulate the activity of ...
Phage therapy of perinephric abscess in kidney transplantation recipients caused by drug-resistant Pseudomonas aeruginosa [0.03%]
用于器官移植患者由药物耐药性铜绿假单胞菌引起的肾周脓肿的噬菌体治疗
Jiazhen Liu,Shuguang Lu,Juan Bao et al.
Jiazhen Liu et al.
Perinephric abscess, a common complication after kidney transplantation, often results from drug-resistant bacterial infections and is notoriously difficult to treat. Phage therapy has emerged as a promising alternative for such resistant i...