Rapid, automated, and reliable antimicrobial susceptibility test from positive blood culture by CAST-R [0.03%]
CAST-R:快速、可靠且自动化地从阳性血液培养基中进行抗菌药物敏感性试验
Pengfei Zhu,Lihui Ren,Ying Zhu et al.
Pengfei Zhu et al.
Antimicrobial susceptibility tests (ASTs) are pivotal in combating multidrug resistant pathogens, yet they can be time-consuming, labor-intensive, and unstable. Using the AST of tigecycline for sepsis as the main model, here we establish an...
A novel Methylomirabilota methanotroph potentially couples methane oxidation to iodate reduction [0.03%]
一种新型甲基米尔细菌型甲烷营养菌可将甲烷氧化与碘酸盐还原耦合
Baoli Zhu,Clemens Karwautz,Stefan Andrei et al.
Baoli Zhu et al.
Methane oxidizing microbes play a key role in reducing the emission of this potent greenhouse gas to the atmosphere. The known versatility of the recently discovered anaerobic Methylomirabilota methanotrophs is limited. Here, we report a no...
Climate warming restructures seasonal dynamics of grassland soil microbial communities [0.03%]
气候变暖重塑草地土壤微生物群落的季节动态
Xue Guo,Mengting Yuan,Jiesi Lei et al.
Xue Guo et al.
Soil microbial community's responses to climate warming alter the global carbon cycle. In temperate ecosystems, soil microbial communities function along seasonal cycles. However, little is known about how the responses of soil microbial co...
Environmental selection and evolutionary process jointly shape genomic and functional profiles of mangrove rhizosphere microbiomes [0.03%]
环境选择和进化过程共同塑造红树根系微生物组的基因组和功能特征
Xiaoli Yu,Qichao Tu,Jihua Liu et al.
Xiaoli Yu et al.
Mangrove reforestation with introduced species has been an important strategy to restore mangrove ecosystem functioning. However, how such activities affect microbially driven methane (CH4), nitrogen (N), and sulfur (S) cycling of rhizosphe...
Widespread Bathyarchaeia encode a novel methyltransferase utilizing lignin-derived aromatics [0.03%]
广泛存在的Bathyarchaeia编码一种利用木质素衍生芳香物的新型甲基转移酶
Tiantian Yu,Haining Hu,Xianhong Zeng et al.
Tiantian Yu et al.
Lignin degradation is a major process in the global carbon cycle across both terrestrial and marine ecosystems. Bathyarchaeia, which are among the most abundant microorganisms in marine sediment, have been proposed to mediate anaerobic lign...
Yoichi Kamagata
Yoichi Kamagata
Assessing mechanisms for microbial taxa and community dynamics using process models [0.03%]
利用过程模型评估微生物类群和群落动态的机制
Linwei Wu,Yunfeng Yang,Daliang Ning et al.
Linwei Wu et al.
Disentangling the assembly mechanisms controlling community composition, structure, distribution, functions, and dynamics is a central issue in ecology. Although various approaches have been proposed to examine community assembly mechanisms...
Protective efficacy of a universal influenza mRNA vaccine against the challenge of H1 and H5 influenza A viruses in mice [0.03%]
一种通用流感mRNA疫苗对小鼠防御H1和H5型流感病毒攻击的保护效力研究
Yulei Li,Xi Wang,Xi Zeng et al.
Yulei Li et al.
Current influenza vaccines need to be updated annually owing to constant antigenic drift in the globular head of the viral surface hemagglutinin (HA) glycoprotein. The immunogenic subdominant stem domain of HA is highly conserved and can be...
Roadmap to tackle antibiotic resistance in the environment under the One Health framework [0.03%]
“同一健康”框架下环境抗生素抗性治理路线图
Liguan Li,Tong Zhang
Liguan Li
Antibiotic resistance has been recognized as a major challenge worldwide for humans. "One Health" has been recognized as a key concept for containment of antibiotic resistance. Under the framework, the role of the environment in the develop...
Dual functions: A coumarin-chalcone conjugate inhibits cyclic-di-GMP and quorum-sensing signaling to reduce biofilm formation and virulence of pathogens [0.03%]
双重功能：一种香豆素-查尔康因缀合物抑制环二鸟苷酸和群体感应信号，以减少病原菌生物被膜的形成和致病性
Yu Zhang,Pramod Bhasme,Dinesh S Reddy et al.
Yu Zhang et al.
Antibiotic resistance or tolerance of pathogens is one of the most serious global public health threats. Bacteria in biofilms show extreme tolerance to almost all antibiotic classes. Thus, use of antibiofilm drugs without bacterial-killing ...