Engineering Nannochloropsis oceanica for the production of diterpenoid compounds [0.03%]
工程化海洋小球藻生产二萜类化合物
Zhi-Yan Du,Wajid W Bhat,Eric Poliner et al.
Zhi-Yan Du et al.
Photosynthetic microalgae like Nannochloropsis hold enormous potential as sustainable, light-driven biofactories for the production of high-value natural products such as terpenoids. Nannochloropsis oceanica is distinguished as a particular...
The construction and optimization of engineered yeast chassis for efficient biosynthesis of 8-hydroxygeraniol [0.03%]
高效生物合成8-羟基牻牛儿醇的工程酵母底盘细胞的构建与优化
Yu Zhang,Mengdi Yuan,Xinxin Wu et al.
Yu Zhang et al.
Microbial production of monoterpenoid indole alkaloids (MIAs) provides a sustainable and eco-friendly means to obtain compounds with high pharmaceutical values. However, efficient biosynthesis of MIAs in heterologous microorganisms is hinde...
A deep-sea sulfate-reducing bacterium generates zero-valent sulfur via metabolizing thiosulfate [0.03%]
深海硫酸盐还原菌通过分解硫代硫酸盐生成零价硫
Rui Liu,Yeqi Shan,Shichuan Xi et al.
Rui Liu et al.
Zero-valent sulfur (ZVS) is a crucial intermediate in the sulfur geobiochemical circulation and is widespread in deep-sea cold seeps. Sulfur-oxidizing bacteria are thought to be the major contributors to the formation of ZVS. However, ZVS p...
Unveiling degradation mechanism of PAHs by a Sphingobium strain from a microbial consortium [0.03%]
分离得到的一菌株降解多环芳烃机制研究
Lige Zhang,Huan Liu,Junbiao Dai et al.
Lige Zhang et al.
Polycyclic aromatic hydrocarbons (PAHs) are a class of persistent pollutants with adverse biological effects and pose a serious threat to ecological environments and human health. The previously isolated phenanthrene-degrading bacterial con...
Whole lifecycle observation of single-spore germinated Streptomyces using a nanogap-stabilized microfluidic chip [0.03%]
基于纳米稳腔的微流控芯片用于单孢萌发链霉菌完整生命周期观测研究
Dongwei Chen,Mengyue Nie,Wei Tang et al.
Dongwei Chen et al.
Streptomyces is a model bacterium to study multicellular differentiation and the major reservoir for antibiotics discovery. However, the cellular-level lifecycle of Streptomyces has not been well studied due to its complexity and lack of re...
Integrated identification of growth pattern and taxon of bacterium in gut microbiota via confocal fluorescence imaging-oriented single-cell sequencing [0.03%]
基于共聚焦荧光成像的单细胞测序整合鉴定肠道微生物菌群细菌生长模式和分类单元
Juan Gao,Di Sun,Bei Li et al.
Juan Gao et al.
Despite the fast progress in our understanding of the complex functions of gut microbiota, it is still challenging to directly investigate the in vivo microbial activities and processes on an individual cell basis. To gain knowledge of the ...
Different outer membrane c-type cytochromes are involved in direct interspecies electron transfer to Geobacter or Methanosarcina species [0.03%]
不同的外膜c型细胞色素参与直接跨物种电子传递给菌株或菌株
Dawn E Holmes,Jinjie Zhou,Jessica A Smith et al.
Dawn E Holmes et al.
Direct interspecies electron transfer (DIET) may be most important in methanogenic environments, but mechanistic studies of DIET to date have primarily focused on cocultures in which fumarate was the terminal electron acceptor. To better un...
Maternal and neonatal viromes indicate the risk of offspring's gastrointestinal tract exposure to pathogenic viruses of vaginal origin during delivery [0.03%]
母体和新生儿的病毒组表明，在分娩过程中阴道病原体病毒感染后代胃肠道的风险
Jinfeng Wang,Liwen Xiao,Baichuan Xiao et al.
Jinfeng Wang et al.
A cumulative effect of enterovirus and gluten intake on the risk of celiac disease autoimmunity in infants highlights the significance of viral exposure in early life on the health of children. However, pathogenic viruses may be transmitted...
Jianping Xu
Jianping Xu
Fungi are an integral part of the earth's biosphere. They are broadly distributed in all continents and ecosystems and play a diversity of roles. Here, I review our current understanding of fungal threats to humans and describe the major fa...