The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery [0.03%]
ATG5互作组蛋白证实了网格蛋白介导的囊泡转运与自噬体装配机器之间的联系
Kiren Baines,Kazuaki Yoshioka,Yoh Takuwa et al.
Kiren Baines et al.
Autophagosome formation involves the sequential actions of conserved ATG proteins to coordinate the lipidation of the ubiquitin-like modifier Atg8-family proteins at the nascent phagophore membrane. Although the molecular steps driving this...
Tupaia GBP1 exploits autophagy to restrict herpes simplex virus type 1 infection [0.03%]
Tupaia GBP1通过利用自噬作用限制单纯疱疹病毒1型感染
Macroautophagy/autophagy initiated by STING1 (stimulator of interferon response cGAMP interactor 1) is actively involved in viral infection; and it is known that interferon-inducible guanylate-binding proteins (GBPs) exploit autophagy to de...
Microgravity inhibits autophagy in human capillary endothelial cells in space flight [0.03%]
微重力抑制空间飞行中人毛细血管内皮细胞的自噬
Microgravity and space radiation (SR) are the two environmental factors that most affect human crews in space flight (SF). The endothelium is highly sensitive to gravitational unloading and several health problems reported by astronauts der...