Autophagy selectively clears ER in TNF-α-induced muscle atrophy [0.03%]
自噬选择性清除肿瘤坏死因子TNF-α诱导的肌肉萎缩中的内质网
Ursula K Dueren,Alan An Jung Wei,A Elisabeth Gressler et al.
Ursula K Dueren et al.
Skeletal muscle atrophy is a pathological condition characterized by the progressive loss of muscle mass and function, driven by factors such as disuse, inflammation, and aging. While the ubiquitin-proteasome system is established as the ce...
Correction [0.03%]
改正错误
[This corrects the article DOI: 10.1080/27694127.2024.2306766.]. © 2026 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Grou...
Published Erratum
Autophagy reports. 2026 Mar 3;5(1):2637293. DOI:10.1080/27694127.2026.2637293 2026
Kenny is the adaptor protein for ubiquitin-dependent mitophagy in Drosophila melanogaster [0.03%]
果蝇泛素依赖的线粒体自噬适配蛋白Kenny的鉴定
Hubert Osei Acheampong,Ryan Insolera
Hubert Osei Acheampong
Mitophagy is the selective degradation program for damaged and unnecessary mitochondria to maintain cellular mitostasis and survival. Specific mutations in the mediators for the canonical ubiquitin (ub)-dependent mitophagy pathway have been...
TMEM259/MEMBRALIN is a non-canonical ER-phagy receptor that associates with MAN1B1 and VCP to eliminate viral glycoproteins [0.03%]
TMEM259/MEMBRALIN是非经典的内质网自噬受体,与MAN1B1和VCP相互作用清除病毒糖蛋白
Jim Maurice Camilleri,Jing Zhang,Tao Wang et al.
Jim Maurice Camilleri et al.
Selective autophagy of the endoplasmic reticulum (ER-phagy/reticulophagy) is essential for organelle homeostasis and host defense, yet how ER quality control (ERQC) pathways distinguish viral glycoproteins from misfolded host proteins remai...
Mfi2: an outer mitochondrial membrane mitofissin required for mitophagy [0.03%]
Mfi2:一种外线粒体膜分噬蛋白,参与线粒体自噬作用
Kentaro Furukawa,Tatsuro Maruyama,Yuji Sakai et al.
Kentaro Furukawa et al.
Mitophagy selectively eliminates damaged or excess mitochondria to maintain mitochondrial homeostasis. During this process, mitochondria need to be fragmented to allow their sequestration within autophagosomes. However, the well-known dynam...
Microautophagy: current understanding of its molecular mechanisms and functions [0.03%]
微自噬:其分子机制和功能的最新研究进展
Yasuyoshi Sakai,Christian Behrends,Jayanta Debnath et al.
Yasuyoshi Sakai et al.
Microautophagy (MI-autophagy) is an umbrella term for intracellular degradative pathways that entail the invagination or protrusion of the limiting membranes of endolysosomal compartments, that is, late endosomes and mammalian lysosomes or ...
Mitofusin MFN2 acts as a molecular sensor preventing protein aggregation and mitophagy, with a protective effect against apoptosis in Charcot-Marie-Tooth type 2A disease [0.03%]
线粒体融合蛋白MFN2作为分子传感器,防止蛋白质聚集和线粒体自噬,并对Charcot-Marie-Tooth 2A型疾病产生抗凋亡的保护作用
Mariana Joaquim,Maike F Dohrn,Arnaud Chevrollier et al.
Mariana Joaquim et al.
Mitochondria are central hubs for cellular fitness, empowered by plastic remodeling of their shape, proteome composition, and/or metabolic state. MFN2 (mitofusin 2) mediates mitochondrial fusion and ensures adaptations in response to metabo...
Marjorie Rolland,Benoît Marchand,Laure Bessy et al.
Marjorie Rolland et al.
Identifying mechanisms underlying chemoresistance is essential for improving the efficacy of chemotherapeutic drugs. Previously, we showed that cancer cells respond to gemcitabine by activating protective signals dependent on the master reg...
A New biosensor illuminates the driving force behind mitochondrial outer membrane rupture [0.03%]
新型生物传感器揭示了线粒体外膜破裂的驱动因素
Wei-Hua Chu,Wei-Chung Chiang
Wei-Hua Chu
In PINK1 (PTEN induced kinase 1)/PRKN (Parkin)-mediated mitophagy, the rupture of the outer mitochondrial membrane (OMM) emerges as a crucial event required for efficient mitochondrial clearance. Mechanistically, OMM rupture exposes inner m...
The nonsense-mediated mRNA decay factor Upf3 negatively regulates bulk autophagy progression in Saccharomyces cerevisiae [0.03%]
酵母Upf3因子通过干扰信息素信号转导负向调控自噬效应分子的活化
Tabassum Ahmad Tasmi,Emily Solomon,Emmanuella Wesome Avogo et al.
Tabassum Ahmad Tasmi et al.
Macroautophagy/Autophagy is a highly conserved mechanism that targets cytoplasmic cargo for degradation and recycling. At present, 45 autophagy-related (ATG) genes have been identified in fungi. Due to this complexity, the autophagy pathway...