Dao-Fu Dai,Ping Kang,Hua Bai
Dao-Fu Dai
The mammalian target of rapamycin (mTOR) is one of the most important signaling pathways that regulate nutrient sensing, cell growth, metabolism, and aging. The mTOR pathway, particularly mTOR complex 1 (mTORC1), has been shown to control a...
Cardiovascular aging: from cellular and molecular changes to therapeutic interventions [0.03%]
心血管衰老：从中枢和分子改变到干预措施
Angeliki Vakka,Junco S Warren,Konstantinos Drosatos
Angeliki Vakka
Progressive age-induced deterioration in the structure and function of the cardiovascular system involves cardiac hypertrophy, diastolic dysfunction, myocardial fibrosis, arterial stiffness, and endothelial dysfunction. These changes are dr...
Payel Sen,Priyatansh Gurha
Payel Sen
Calum A MacRae
Calum A MacRae
Daniel R Goldstein,Ahmed Abdel-Latif
Daniel R Goldstein
Advances in healthcare and improvements in living conditions have led to rising life expectancy worldwide. Aging is associated with excessive oxidative stress, a chronic inflammatory state, and limited tissue healing, all of which result in...
ChatGPT and other artificial intelligence chatbots and biomedical writing [0.03%]
ChatGPT及其他人工智能聊天机器人与生物医学写作
Priyatansh Gurha,Nadeem Ishaq,Ali J Marian
Priyatansh Gurha
Nirjal Mainali,Srinivas Ayyadevara,Akshatha Ganne et al.
Nirjal Mainali et al.
Protein homeostasis, the balance between protein synthesis and degradation, requires the clearance of misfolded and aggregated proteins and is therefore considered to be an essential aspect of establishing a physiologically effective proteo...
CaMKIIδ gene editing- A base hit for the heart [0.03%]
靶向心脏的CaMKIIδ基因编辑——一记基因修正基地修复击TURE的基础上进行。根据提供的英文句子"title: CaMKIIδ gene editing- A base hit for the heart"，其对应的中文翻译应为“CaMKIIδ基因编辑——靶向心脏的一记基因修正基地修复击”。但是，考虑到这句话中包含了特定领域的术语和比喻表达方式，可以适当简化并保持原意的准确传达。因此最终答案建议如下：
中文标题：CaMKIIδ基因编辑——为心脏设计的精准打击
Christopher J Walkey,William R Lagor
Christopher J Walkey
Travis B Lear,Toren Finkel
Travis B Lear
Senescent cell accumulation is increasingly associated with a number of age-related cardiovascular diseases. Now, a new manuscript in Nature Aging suggests that a novel vaccine-based strategy might provide a targeted method to eliminate the...