Proteomic Profiling of Bacterial Extracellular Vesicles for Exploring Ovarian Cancer Biomarkers [0.03%]
细菌外泌体蛋白质组学鉴定及其在卵巢癌生物标志物发现中的应用
Eri Asano-Inami,Akira Yokoi,Kosuke Yoshida et al.
Eri Asano-Inami et al.
Extracellular vesicles (EVs) are present in body fluids and act as disease biomarkers. Emerging evidence has proven that EVs are released not only from mammalian cells but also from bacteria. Ovarian cancer has a dismal prognosis because of...
Generalizability of Enzyme-Based Isolation Approach for Extracellular Vesicles From Traditional Medicinal Plants [0.03%]
基于酶的分离外泌体方法的传统植物普适性研究
Qian Wang,Renwei Jing,Nan Cao et al.
Qian Wang et al.
Extracellular vesicles (EVs) from plants, particularly traditional medicinal plants, have garnered therapeutic interest. However, therapeutic utility requires establishing effective extraction and purification protocols for manufacturing. H...
Effect of a 12-Week Endurance Training Program on Circulating Extracellular Vesicle Proteome in Sedentary Adults With Obesity [0.03%]
12周耐力训练对久坐肥胖成年人外泌体蛋白组的影响研究
Geoffrey Warnier,Sophie van Doorslaer de Ten Ryen,Camille Lannoy et al.
Geoffrey Warnier et al.
Systemic inflammatory state found in obesity increases the risk of developing numerous diseases. While endurance training seems effective to reduce this inflammation, the underlying mechanisms are not fully understood. Among those, extracel...
Extracellular Vesicles in Serum Carry Trop2 Protein as a Potential Molecular Indicator in Prostate Cancer [0.03%]
血清外泌体携带Trop2蛋白作为潜在的分子标志物在前列腺癌中的作用
Prima Dewi Sinawang,Mehmet O Ozen,Shiqin Liu et al.
Prima Dewi Sinawang et al.
Extracellular vesicles (EVs) are lipid nano-to-micro-sized vesicles increasingly studied for their role in intercellular communication and their potential as minimally invasive molecular indicators in various diseases. However, challenges r...
Sex-Specific Differences in the Secretome of Oligodendrocyte Progenitor Cells Post Hyperoxic Stress [0.03%]
缺氧损伤后寡突胶质前体细胞性别差异性分泌组学研究
Donna Elizabeth Sunny,Elke Hammer,Stephan Michalik et al.
Donna Elizabeth Sunny et al.
Cerebral oxygenation differences in the neonatal period of human preterm infants, along with sex-specific differences in combating oxidative stress, can lead to disruption of normal oligodendrocyte maturation and function, which in turn can...
Tumoural Hypoxic Extracellular Vesicles Foster a Protective Microenvironment in Triple-Negative Breast Cancer [0.03%]
三阴性乳腺癌肿瘤低氧外泌体促进保护性微环境
Bianca Cruz Pachane,Pedro Henrique Teixeira Bottaro,Aline Maria Machado et al.
Bianca Cruz Pachane et al.
The highly metastatic triple-negative breast cancer (TNBC) relies on the tumour microenvironment (TME) to maintain phenotypic heterogeneity and progression. Extracellular vesicles from hypoxic TNBC (EVh) have been previously shown to facili...
MicroRNA (miRNA) in Plasma Small Extracellular Vesicles (sEV) as Potential Early Indicators of Dairy Cow Subfertility [0.03%]
血浆小型细胞外囊泡中的微小核糖核酸作为提示奶牛亚育性的潜在早期指标
Pevindu Abeysinghe,Natalie Turner,Holly Flay et al.
Pevindu Abeysinghe et al.
Pregnancy and live birth rates are commonly used metrics to define fertility in humans and animals. The impact of aberrant microRNA (miRNA) expression on fertility-related genes represents a significant knowledge gap in understanding post-t...
Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses [0.03%]
人类真菌感染来源的细胞外囊泡：免疫反应中的关键因素
Caroline P de Rezende,Patrick W S Santos,Renan A Piraine et al.
Caroline P de Rezende et al.
Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate in...
Surface-Engineered Natural Killer Cell-Derived Small Extracellular Vesicles Induce Potent Anti-Tumour Effects in Lung Cancer Cells [0.03%]
表面工程的自然杀伤细胞衍生的小细胞外囊泡可诱导肺癌细胞产生强大的抗肿瘤效应
Sung-Min Kang,Dokyung Jung,Soojeong Noh et al.
Sung-Min Kang et al.
Small extracellular vesicles (sEVs) derived from natural killer (NK) cells possess inherent anti-tumour activity and offer the advantages of cell-free therapy. In this study, we genetically engineered NK-sEVs to express interleukin 15 (IL15...
Extracellular Vesicles for the Treatment of Alzheimer's Disease: A Systematic Review [0.03%]
治疗阿尔茨海默病的外泌体：系统性综述
Jolene Phelps,Amanda Orr,Katherine S Elvira et al.
Jolene Phelps et al.
The development of novel treatments that restore brain function and improve patient outcomes for Alzheimer's disease (AD) is necessary, given the complications and lack of improvement in recently approved amyloid beta (Aβ)-targeting drugs....