Molecular Characterization of Extracellular Vesicles From Human B Cell Lymphomas: Methodological Comparison to Vesicles From Patient Serum [0.03%]
人B细胞淋巴瘤的外泌体分子特征及其与患者血清中外泌体的方法学比较研究
Md Nasir Uddin Badal,Tiia Koivula,Md Khirul Islam et al.
Md Nasir Uddin Badal et al.
Human B cell lymphomas represent a clinically heterogeneous disease group with lack of liquid biomarkers for specific subtype classification. Extracellular vesicles (EVs) hold promises as non-invasive biomarkers, yet their subtype-specific ...
Extracellular Vesicle Properties and Functions Are Defined by the Originating Cell's Fitness Status [0.03%]
细胞的适应状态决定其释放的细胞外囊泡的属性及功能
Stephanie Leyk,Imke Liebold,Clarissa Lanzloth et al.
Stephanie Leyk et al.
Recent studies have focused on the role of dying cells in modulating immune function and shaping the local microenvironment. Apoptotic cells release various extracellular vesicles (EVs), such as exosomes and microvesicles, and form apoptoti...
Extracellular Particles Derived From Mesenchymal Stromal Cells Reduce Pseudomonas aeruginosa Lung Infection and Inflammation in Mice [0.03%]
来源于间充质基质细胞的胞外颗粒可减轻小鼠绿脓杆菌肺部感染和炎症
Sharanya Sarkar,Roxanna Barnaby,Zachary Faber et al.
Sharanya Sarkar et al.
The World Health Organization and the U.S. Centre for Disease Control and Prevention have reported that antibiotic-resistant infections with Pseudomonas aeruginosa present a significant health risk worldwide. In the genetic disease cystic f...
Separation Methods Affect Glycan Patterns in Extracellular Vesicle Preparations From Canine Osteoblasts and Osteosarcoma Cells [0.03%]
分离方法影响犬成骨细胞和骨肉瘤细胞来源的外泌体糖类模式
Daniela Cortes Galvez,Silvio Kau-Strebinger,Simone Gabner et al.
Daniela Cortes Galvez et al.
Extracellular vesicles (EVs) are nanosized, membrane-enclosed particles released by cells, facilitating intercellular communication via the transfer of bioactive molecules from producing to recipient cells. EVs are involved in several physi...
Extracellular Vesicle-Mediated Delivery of Constrained Peptides Disrupts the Pathogenic Interaction of LRRK2-FADD in Parkinson's Disease [0.03%]
外泌体介导的细胞穿膜肽递送破坏PARKINSON病中LRRK2-FADD病理互作
Yaochao Zheng,Brian Joseph Jurgielewicz,Leah G Helton et al.
Yaochao Zheng et al.
The interaction between mutated leucine-rich repeat kinase 2 (LRRK2) and the death adaptor protein FADD accounts for apoptotic death of dopaminergic neurons in familial Parkinson's disease (PD) driven by LRRK2 mutations. Disrupting this pat...
Natasa Zarovni,Konstantin Glebov
Natasa Zarovni
Development of a Novel Extracellular Vesicle-Based Biomarker Approach for Pediatric High-Grade Glioma [0.03%]
新型外泌体生物标志物方法在儿童高分级胶质瘤中的应用开发研究
Adriana Fernandez Garcia,Poorvi Iyer,Pablo Ashi et al.
Adriana Fernandez Garcia et al.
Pediatric high-grade gliomas (pHGGs) account for 20% of childhood brain tumours and are associated with poor survival. Currently, pHGG detection relies on MRI, a costly and time-consuming procedure. Extracellular vesicles (EVs) carry molecu...
Tissue-Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective [0.03%]
组织特异性外泌体富集液检测：探索液体活检的新视角
Biancamaria Pierri,Erez Eitan,Kenneth W Witwer et al.
Biancamaria Pierri et al.
Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising ta...
Unconventional Secretion of Angiogenic Sonic Hedgehog-Containing Extra-Large Extracellular Vesicles is Driven by PI3K-Rab18-GDP Signalling [0.03%]
PI3K-Rab18-GDP信号驱动血管生成型Sonic Hedgehog含大型细胞外囊泡的非经典分泌路径
Shuo Wang,Rio Imai,Yuya Kaneko et al.
Shuo Wang et al.
Extra-large extracellular vesicles (XLEVs), with diameters > 600 nm, are increasingly recognised as mediators of specialized modes of intercellular communication; however, the molecular mechanisms governing their biogenesis and functional r...
Placental Extracellular Vesicles Exhibit Reduced Neurogenic Potential Linked to Changes in Their miRNA Landscape Upon HCMV Infection [0.03%]
HCMV感染下调胎盘外泌体的神经源性潜能与其miRNA图谱改变有关
Charlène Martin,Hélène Martin,Mathilde Bergamelli et al.
Charlène Martin et al.
Extracellular vesicles (EVs) are key mediators of maternal-foetal communication, regulating placental function and foetal development through the transfer of bioactive molecules. Although placental EVs play a crucial role in placental funct...