Analysis of extracellular vesicle microRNA profiles reveals distinct blood and lymphatic endothelial cell origins [0.03%]
外泌体微RNAs分析揭示了不同血管内皮细胞起源
Marianne Pultar,Johannes Oesterreicher,Jaana Hartmann et al.
Marianne Pultar et al.
Extracellular vesicles (EVs) are crucial mediators of cell-to-cell communication in physiological and pathological conditions. Specifically, EVs released from the vasculature into blood were found to be quantitatively and qualitatively diff...
The diffusion of normal skin wound myofibroblast-derived microvesicles differs according to matrix composition [0.03%]
正常皮肤伤口肌成纤维细胞源性微囊的扩散根据基质组成而不同
Syrine Arif,Sébastien Larochelle,Benjamin Trudel et al.
Syrine Arif et al.
Microvesicles (MVs) are a subtype of extracellular vesicles that can transfer biological information over long distances, affecting normal and pathological processes including skin wound healing. However, the diffusion of MVs into tissues c...
Distinct targeting and uptake of platelet and red blood cell-derived extracellular vesicles into immune cells [0.03%]
血小板和红细胞来源的囊泡对免疫细胞表现出不同的靶向性和内吞作用
Petra Ilvonen,Reetta Pusa,Kai Härkönen et al.
Petra Ilvonen et al.
Blood-derived extracellular vesicles (EVs) hold great therapeutic potential. As blood contains mixed EV populations, it is challenging to study EVs originating from different cells separately. Blood cell concentrates manufactured in blood b...
Extracellular vesicle biogenesis of three-dimensional human pluripotent stem cells in a novel Vertical-Wheel bioreactor [0.03%]
新型垂直车式生物反应器中三维人多能干细胞的细胞外囊泡生成
Laureana Muok,Li Sun,Colin Esmonde et al.
Laureana Muok et al.
Extracellular vesicles (EVs) secreted by human-induced pluripotent stem cells (hiPSCs) have great potential as cell-free therapies in various diseases, including prevention of blood-brain barrier senescence and stroke. However, there are st...
Proteome encoded determinants of protein sorting into extracellular vesicles [0.03%]
编码蛋白质分选至细胞外囊泡的蛋白组学决定因素
Katharina Waury,Dea Gogishvili,Rienk Nieuwland et al.
Katharina Waury et al.
Extracellular vesicles (EVs) are membranous structures released by cells into the extracellular space and are thought to be involved in cell-to-cell communication. While EVs and their cargo are promising biomarker candidates, sorting mechan...
Intracellular localisation and extracellular release of Y RNA and Y RNA binding proteins [0.03%]
细胞内定位和细胞外释放Y RNA及Y RNA结合蛋白
Tom A P Driedonks,Sarah Ressel,Thi Tran Ngoc Minh et al.
Tom A P Driedonks et al.
Cells can communicate via the release and uptake of extracellular vesicles (EVs), which are nano-sized membrane vesicles that can transfer protein and RNA cargo between cells. EVs contain microRNAs and various other types of non-coding RNA,...
Identification of stable reference genes for relative quantification of long RNA expression in urinary extracellular vesicles [0.03%]
鉴定尿液外泌体长RNA相对定量的稳定参考基因
Xiao-Xiao Zhu,An-Ran Shen,Ning Li et al.
Xiao-Xiao Zhu et al.
Urinary extracellular vesicles (uEVs) are rich in valuable biomolecule information which are increasingly recognized as potential biomarkers for various diseases. uEV long RNAs are among the critical cargos capable of providing unique trans...
Gestational age at birth influences protein and RNA content in human milk extracellular vesicles [0.03%]
分娩时的胎龄影响人类乳汁细胞外囊泡中的蛋白和RNA含量
Brett Vahkal,Illimar Altosaar,Eric Tremblay et al.
Brett Vahkal et al.
Human milk extracellular vesicles (HM EVs) are proposed to protect against disease development in infants. This protection could in part be facilitated by the bioactive EV cargo of proteins and RNA. Notably, mothers birth infants of differe...
TRPC3 signalling contributes to the biogenesis of extracellular vesicles [0.03%]
TRPC3信号转导参与细胞外囊泡的产生
Elise H Padbury,Štefan Bálint,Emanuela Carollo et al.
Elise H Padbury et al.
Extracellular vesicles (EVs) contribute to a wide range of pathological processes including cancer progression, yet the molecular mechanisms underlying their biogenesis remain incompletely characterized. The development of tetraspanin-based...
Differential response of placental cells to high D-glucose and its impact on extracellular vesicle biogenesis and trafficking via small GTPase Ras-related protein RAB-7A [0.03%]
高D-葡萄糖对胎盘细胞的差异反应及其对小GTP酶RAB-7A介导的胞外囊泡发生和运输的影响
Carlos Palma,Andrew Lai,Katherin Scholz-Romero et al.
Carlos Palma et al.
Placental extracellular vesicles (EVs) can be found in the maternal circulation throughout gestation, and their concentration, content and bioactivity are associated with pregnancy outcomes, including gestational diabetes mellitus (GDM). Ho...