Adipose derived stem cell extracellular vesicles modulate primary human macrophages to an anti-inflammatory phenotype in vitro [0.03%]
人 adipose 基质干细胞外泌体逆转录人体巨噬细胞的表型
Emma K C Symonds,Bianca Black,Alexander Brown et al.
Emma K C Symonds et al.
EVs released by adipose derived stem cells (ADSCs) have shown promise as a therapeutic for tissue repair because of their purported immune-regulatory properties. Extracellular vesicles (EVs) from ADSCs could be beneficial in improving graft...
TP53 mutations correlate with the non-coding RNA content of small extracellular vesicles in melanoma [0.03%]
TP53突变与黑色素瘤小细胞外囊泡非编码RNA含量相关性研究
Maureen Labbé,Estelle Menoret,Franck Letourneur et al.
Maureen Labbé et al.
Non-coding RNAs (ncRNAs) are important regulators of gene expression. They are expressed not only in cells, but also in cell-derived extracellular vesicles (EVs). The mechanisms controlling their loading and sorting remain poorly understood...
A commentary on: TDO2-augmented fibroblasts secrete EVs enriched in immunomodulatory Y-derived small RNA [0.03%]
关于TDO2增强的成纤维细胞分泌富含Y染色体衍生的小RNA的外泌体的述评
Clarissa Sastrawidjaya,Phuong H D Nguyen
Clarissa Sastrawidjaya
Characterising the HLA-I immunopeptidome of plasma-derived extracellular vesicles in patients with melanoma [0.03%]
黑色素瘤患者血浆来源的外泌体HLA-I免疫肽组学特征分析
Caitlin Boyne,Abigail Coote,Silvia Synowsky et al.
Caitlin Boyne et al.
Extracellular vesicles (EVs) frequently express human leukocyte antigen class I (HLA-I) molecules. The immunopeptidomes presented on EV HLA-I are being mapped to provide key information on both specific cancer-related peptides, and for larg...
Profile of matrix-entrapped extracellular vesicles of microenvironmental and infiltrating cell origin in decellularized colorectal cancer and adjacent mucosa [0.03%]
脱细胞结直肠癌及邻近黏膜中来自微环境和浸润细胞的基质截获的外泌体特征剖析
Sarah Tassinari,Edoardo DAngelo,Federico Caicci et al.
Sarah Tassinari et al.
Cellular elements that infiltrate and surround tumours and pre-metastatic tissues have a prominent role in tumour invasion and growth. The extracellular vesicles specifically entrapped and stored within the extracellular matrix (ECM-EVs) ma...
Dysregulation of intercellular communication in vitro and in vivo via extracellular vesicles secreted by pancreatic duct adenocarcinoma cells and generated under the influence of the AG9 elastin peptide-conditioned microenvironment [0.03%]
AG9弹性蛋白肽调理的微环境影响下胰腺导管腺癌细胞分泌的细胞外囊泡通过调节体内外细胞间通讯导致肿瘤促进表型改变
Lise Nannan,Salomé Decombis,Christine Terryn et al.
Lise Nannan et al.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor prognosis due to its highly metastatic profile. Intercellular communication between cancer and stromal cells via extracellular vesicles (EVs) is crucial for the p...
ELISA-based detection of immunoglobulins against extracellular vesicles in blood plasma [0.03%]
基于ELISA的血浆外泌体免疫球蛋白检测方法
Tom A P Driedonks,Linglei Jiang,Olesia Gololobova et al.
Tom A P Driedonks et al.
Extracellular vesicles (EVs) are intensively investigated for their therapeutic potential and application as drug delivery vehicle. A broad perception of favourable safety profiles and low immunogenicity make EVs an attractive alternative t...
Extracellular vesicles from bodily fluids for the accurate diagnosis of Parkinson's disease and related disorders: A systematic review and diagnostic meta-analysis [0.03%]
来自体液的细胞外囊泡在帕金森病及相关障碍物精确诊断中的作用:系统性综述与诊断元分析
Hash Brown Taha,Aleksander Bogoniewski
Hash Brown Taha
Parkinsonian disorders, including Parkinson's disease (PD), multiple system atrophy (MSA), dementia with Lewy body (DLB), corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP) are often misdiagnosed due to overlapping symptom...
Defective mitochondria-lysosomal axis enhances the release of extracellular vesicles containing mitochondrial DNA and proteins in Huntington's disease [0.03%]
缺陷的线粒体-溶酶体轴可增强含有线粒体DNA和蛋白质的细胞外囊泡的释放在亨廷顿舞蹈病中的作用
Margarida Beatriz,Rita Vilaça,Sandra I Anjo et al.
Margarida Beatriz et al.
Mitochondrial and autophagy dysfunction are mechanisms proposed to be involved in the pathogenesis of several neurodegenerative diseases. Huntington's disease (HD) is a progressive neurodegenerative disorder associated with mutant Huntingti...
Nutrient smuggling: Commensal gut bacteria-derived extracellular vesicles scavenge vitamin B12 and related cobamides for microbe and host acquisition [0.03%]
营养偷窃:共生肠道细菌来源的胞外囊泡收集维生素B12及相关钴氨素供微生物和宿主获取
Rokas Juodeikis,Emily Jones,Evelyne Deery et al.
Rokas Juodeikis et al.
The processes by which bacteria proactively scavenge essential nutrients in crowded environments such as the gastrointestinal tract are not fully understood. In this context, we observed that bacterial extracellular vesicles (BEVs) produced...