Comparative and integrated analysis of plasma extracellular vesicle isolation methods in healthy volunteers and patients following myocardial infarction [0.03%]
健康志愿者和心肌梗死患者血浆外泌体分离方法的比较及综合分析
Daan Paget,Antonio Checa,Benedikt Zöhrer et al.
Daan Paget et al.
Plasma extracellular vesicle (EV) number and composition are altered following myocardial infarction (MI), but to properly understand the significance of these changes it is essential to appreciate how the different isolation methods affect...
Anti-cancer bioactivity of sweet basil leaf derived extracellular vesicles on pancreatic cancer cells [0.03%]
甜罗勒叶源外泌体的抗胰腺癌活性研究
Uday Chintapula,Daniel Oh,Cristina Perez et al.
Uday Chintapula et al.
Most living organisms secrete tiny lipid bilayer particles encapsulating various biomolecular entities, including nucleic acids and proteins. These secreted extracellular vesicles (EVs) are shown to aid in communication between cells and th...
Lipidomics and biodistribution of extracellular vesicles-secreted by hepatocytes from Zucker lean and fatty rats [0.03%]
Zucker瘦型和脂肪型大鼠肝细胞分泌的外泌体脂质组学及分布研究
Maria Azparren-Angulo,Justyna Mleczko,Oihane E Alboniga et al.
Maria Azparren-Angulo et al.
Extracellular vesicles (EVs) have been involved in metabolic syndrome, although their specific role in the development of the pathology is still unknown. To further study the role of EVs, we have analysed by Raman tweezers microspectroscopy...
Differentiation of large extracellular vesicles in oral fluid: Combined protocol of small force centrifugation and sedimentation pattern analysis [0.03%]
口腔液体中大胞外囊泡的分离：低强度离心与沉淀模式分析联合方案
Takamasa Kawano,Kohji Okamura,Hiroki Shinchi et al.
Takamasa Kawano et al.
Extracellular vesicles (EVs) in biofluids are highly heterogeneous entities in terms of their origins and physicochemical properties. Considering the application of EVs in diagnostic and therapeutic fields, it is of extreme importance to es...
Scalable purification of extracellular vesicles with high yield and purity using multimodal flowthrough chromatography [0.03%]
一种利用多模式流穿色谱法高效、高纯度制备外泌体的方法
Scott E Bonner,Simonides I van de Wakker,William Phillips et al.
Scott E Bonner et al.
Extracellular vesicles (EVs) are cell derived membranous nanoparticles. EVs are important mediators of cell-cell communication via the transfer of bioactive content and as such they are being investigated for disease diagnostics as biomarke...
RAB31 drives extracellular vesicle fusion and cancer-associated fibroblast formation leading to oxaliplatin resistance in colorectal cancer [0.03%]
RAB31通过驱动细胞外囊泡融合和癌相关成纤维细胞形成导致结直肠癌顺铂耐药
Yu-Chan Chang,Yi-Fang Yang,Chien-Hsiu Li et al.
Yu-Chan Chang et al.
Epithelial-mesenchymal transition (EMT) is associated with tumorigenesis and drug resistance. The Rab superfamily of small G-proteins plays a role in regulating cell cytoskeleton and vesicle transport. However, it is not yet clear how the R...
Proteomic profiling of tumour tissue-derived extracellular vesicles in colon cancer [0.03%]
结肠癌肿瘤组织衍生外泌体的蛋白质组分析
Aleksander Cvjetkovic,Nasibeh Karimi,Rossella Crescitelli et al.
Aleksander Cvjetkovic et al.
Colon cancer is one of the most commonly occurring tumours among both women and men, and over the past decades the incidence has been on the rise. As such, the need for biomarker identification as well as an understanding of the underlying ...
ISG15 mediates the function of extracellular vesicles in promoting ovarian cancer progression and metastasis [0.03%]
ISG15介导外泌体促进卵巢癌进展和转移的功能
Kalpana Deepa Priya Dorayappan,Vincent Wagner,Dongju Park et al.
Kalpana Deepa Priya Dorayappan et al.
The interferon stimulated gene 15 (ISG15), a ubiquitin like protein and its conjugates have been implicated in various human malignancies. However, its role in ovarian cancer progression and metastasis is largely unknown. In high grade sero...
Optimal isolation of extracellular vesicles from pleural fluid and profiling of their microRNA cargo [0.03%]
胸腔积液中细胞外囊泡的最优分离及其微环境中miRNA谱分析
Tian Mun Chee,Hannah E O&#x;Farrell,Luize G Lima et al.
Tian Mun Chee et al.
Pleural effusion occurs in both benign and malignant pleural disease. In malignant pleural effusions, the diagnostic accuracy and sensitivity of pleural fluid cytology is less than perfect, particularly for the diagnosis of malignant pleura...
Cell culture-derived extracellular vesicles: Considerations for reporting cell culturing parameters [0.03%]
基于细胞培养的外泌体：报告细胞培养参数的注意事项
Faezeh Shekari,Faisal J Alibhai,Hossein Baharvand et al.
Faezeh Shekari et al.
Cell culture-conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs) for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect the biochemical composition, release and possibly the...