Choice of blood collection methods influences extracellular vesicles counts and miRNA profiling [0.03%]
血细胞采集方法影响外泌体数量和miRNA图谱
Vivian Tran,Getulio Pereira de Oliveira-Jr,Stephanie Chidester et al.
Vivian Tran et al.
Circulating RNAs have been investigated systematically for over 20 years, both as constituents of circulating extracellular vesicles (EVs) or, more recently, non-EV RNA carriers, such as exomeres and supermeres. The high level of variabilit...
Comparison of nanoimaging and nanoflow based detection of extracellular vesicles at a single particle resolution [0.03%]
基于纳米成像和纳流的单颗粒分辨率检测细胞外囊泡的比较研究
Shihan Xu,Zhengrong Zhang,Bridgette C Melvin et al.
Shihan Xu et al.
The characterization of single extracellular vesicle (EV) has been an emerging tool for the early detection of various diseases despite there being challenges regarding how to interpret data with different protocols or instruments. In this ...
Small extracellular vesicles contain metals and transfer metal intercellularly [0.03%]
小型细胞外囊泡含金属并在细胞间转运金属
Adityas Purnianto,Celeste Mawal,Mitali M Kulkarni et al.
Adityas Purnianto et al.
Cells have developed a highly regulated system for the uptake, transport, utilization, storage, and export of metals, ensuring the maintenance of cellular homeostasis. Small extracellular vesicles (sEVs) function as a mechanism through whic...
Shining a light on fluorescent EV dyes: Evaluating efficacy, specificity and suitability by nano-flow cytometry [0.03%]
纳米流式细胞仪评估荧光EV染料的有效性、特异性和适用性
Joseph Brealey,Rebecca Lees,Robert Tempest et al.
Joseph Brealey et al.
Extracellular vesicles (EVs) are mediators of intercellular communication, recently recognised for their clinical applications. Accurate characterisation and quantification of EVs are critical for understanding of their function and clinica...
Exploring the potential of the convergence between extracellular vesicles and CAR technology as a novel immunotherapy approach [0.03%]
探索细胞外囊泡与CAR技术在新型免疫治疗中的融合潜力
Ofir Bar,Angel Porgador,Tomer Cooks
Ofir Bar
Cancer therapy is a dynamically evolving field, witnessing the emergence of innovative approaches that offer a promising outlook for patients grappling with persistent disease. Within the realm of therapeutic exploration, chimeric antigen r...
Urinary extracellular vesicles as a monitoring tool for renal damage in patients not meeting criteria for chronic kidney disease [0.03%]
不符合慢性肾脏病标准的患者的尿液胞外囊泡作为监测肾损害的工具
Miriam Anfaiha-Sanchez,Aranzazu Santiago-Hernandez,Juan Antonio Lopez et al.
Miriam Anfaiha-Sanchez et al.
Background: Current definition of chronic kidney disease (CKD) identifies only advanced stages, but effective management demands early detection. Urinary albumin-to-creatinine ratio (ACR) 30 mg/g is a cut-off point for CK...
Dynamics of microRNA secreted via extracellular vesicles during the maturation of embryonic stem cell-derived retinal pigment epithelium [0.03%]
胚胎干细胞源性视网膜色素上皮细胞成熟过程中胞外囊泡分泌的microRNA的动力学规律研究
Dimitrios Pollalis,Gopa Kumar Gopinadhan Nair,Justin Leung et al.
Dimitrios Pollalis et al.
Retinal pigment epithelial (RPE) cells are exclusive to the retina, critically multifunctional in maintaining the visual functions and health of photoreceptors and the retina. Despite their vital functions throughout lifetime, RPE cells lac...
5-Fluorouracil treatment represses pseudouridine-containing miRNA export into extracellular vesicles [0.03%]
5-氟尿嘧啶治疗抑制假尿苷含有的microRNA进入细胞外囊泡
Shimian Qu,Hannah M Nelson,Xiao Liu et al.
Shimian Qu et al.
5-Fluorouracil (5-FU) has been used for chemotherapy for colorectal and other cancers for over 50 years. The prevailing view of its mechanism of action is inhibition of thymidine synthase leading to defects in DNA replication and repair. Ho...
Lipid droplets and small extracellular vesicles: More than two independent entities [0.03%]
脂滴和小型细胞外囊泡：不仅仅是两个独立的实体
Géraldine C Genard,Luca Tirinato,Francesca Pagliari et al.
Géraldine C Genard et al.
Despite increasing knowledge about small extracellular vesicle (sEV) composition and functions in cell-cell communication, the mechanism behind their biogenesis remains unclear. Here, we reveal for the first time that sEV biogenesis and rel...
Exploring the potential of in vitro extracellular vesicle generation in reproductive biology [0.03%]
体外生成外泌体在生殖生物学中的应用前景探究
Roksan Franko,Marcia de Almeida Monteiro Melo Ferraz
Roksan Franko
The interest in the growing field of extracellular vesicle (EV) research highlights their significance in intercellular signalling and the selective transfer of biological information between donor and recipient cells. EV studies have provi...