RNY1 Is Heterogeneously Partitioned in Inflamed Airway Fluid and Modulates Pro-Inflammatory Macrophage Transcriptional Programming [0.03%]
RNY1在炎症气道液体中异质分布并调节促炎性巨噬细胞转录程序调控
Cherie E Saffold,Antiana C Richardson,Heather H Pua
Cherie E Saffold
YRNAs are small noncoding RNAs that are abundant in the extracellular space. Prior research has shown that YRNAs are present in most biofluids and that their levels fluctuate during disease. Yet our understanding of YRNA dynamics in the con...
Investigating the Effect of Ginger-Derived Nanovesicles on the Growth and Metabolic Activity of Bacteroides thetaiotaomicron: An Isothermal Microcalorimetric Study [0.03%]
姜提取物衍生的纳米囊泡对Bacteroides thetaiotaomicron生长及代谢活性影响的等温微量热研究
Francesca Loria,Anna Kattel,Marina Junusova et al.
Francesca Loria et al.
Plant-derived extracellular vesicles (EVs) have shown numerous health benefits, including modulation of the human gut microbiota. Herein, we employed isothermal microcalorimetry (IMC) to explore the effects of ginger-derived nanovesicles (G...
Engineered Red Blood Cell-Derived Extracellular Vesicles With Klotho Peptide Protect the Kidney From Fibrosis [0.03%]
工程化血管生成红细胞衍生的外泌体通过Klotho多肽保护肾脏免于纤维化损伤
Tunahan Ergunay,Alessia Brossa,Michela Arena et al.
Tunahan Ergunay et al.
Chronic kidney disease is characterized by progressive tubular injury and fibrosis, ultimately leading to irreversible loss of renal function. Extracellular vesicles (EVs) have emerged as promising therapeutic platforms due to their biocomp...
Investigation Into the Collection and Isolation Workflows of Extracellular Vesicles From Tears [0.03%]
关于从眼泪中收集和分离细胞外囊泡的工作流程的研究
Nikolay Boychev,Mudigunda V Sushma,Vincent Yeung et al.
Nikolay Boychev et al.
Tear extracellular vesicles (tEVs) are a promising source of biomarkers for ocular and systemic diseases. Standardized approaches for their collection and isolation remain underdeveloped. Contact lenses (CLs), routinely used for vision corr...
Exosome Secretion Drives Chemo-Resistance of Temozolomide in Glioblastoma [0.03%]
胶质母细胞瘤中分泌的小囊泡体驱动替莫唑胺耐药性
Wenpei Li,Shaoping Jiang,Kun Liu et al.
Wenpei Li et al.
Temozolomide (TMZ) is a first-line chemotherapeutic agent for the treatment of glioblastoma (GBM), while a majority of patients do not effectively respond to TMZ owing to the multiple resistance mechanisms. In this study, we found that TMZ ...
Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics [0.03%]
saliva外泌体：液态活检新模式
Kwanele Xulu,Usri H Ibrahim,Irene Mackraj et al.
Kwanele Xulu et al.
Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently ga...
Characterisation and Comparative Evaluation of miRNA Contained in Small Extracellular Vesicles Isolated From Bovine Milk and Whey [0.03%]
含于牛乳和乳清中小胞外囊泡中的miRNA的表征及其比较评价
Caterina Trevisan,Giulia Polacchini,Bruno Stefanon et al.
Caterina Trevisan et al.
Small extracellular vesicles (EVs) from bovine milk and whey are emerging as biologically active carriers of microRNA (miRNA), yet their composition and variability among different dairy sources remain incompletely understood. We conducted ...
Bovine Milk-Derived Extracellular Vesicles as Emerging Drug Delivery Platforms: Current Advances, Applications and Challenges [0.03%]
牛乳外泌体作为新兴药物递送平台：当前进展、应用和挑战
Martina Brattini,Michelle D&#x;Urso,Sofia Mariotto et al.
Martina Brattini et al.
Extracellular vesicles (EVs) are nanosized lipid bilayer particles naturally secreted by cells, mediating intercellular communication and transporting diverse bioactive molecules. Among alternative EV sources, bovine milk-derived EVs (BMEVs...
Stage-Specific Molecular Cargo of Schwann Cell-Derived Extracellular Vesicles is Associated With Peripheral Nerve Repair [0.03%]
施万细胞来源的胞外囊泡分阶段携带不同的分子货物参与周围神经修复
Manju Sharma,Supasek Kongsomros,Maulee Sheth et al.
Manju Sharma et al.
Schwann cells (SCs) play a critical role in peripheral nerve regeneration, undergoing dynamic phenotype transitions from myelinating to repair stages following injury. While SC-derived extracellular vesicles (SC-EVs) have emerged as key med...
Cell Envelope Remodeling and Lipid Metabolism Coordinate Extracellular Vesicle Output in Mycobacterium Tuberculosis [0.03%]
结核分枝杆菌胞壁重塑和脂质代谢协调分枝杆菌囊泡的分泌释放过程
José L Serrano-Mestre,Laura Lerma,Lucía Vázquez-Iniesta et al.
José L Serrano-Mestre et al.
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global cause of death due to the pathogen's highly adaptive physiology and its ability to manipulate host immunity. Despite extensive study, our understanding ...