UKEV forum 2024: The UK Society for Extracellular Vesicle annual meeting - bridging innovation and impact [0.03%]
英国 extracellular vesicle 社区 2024 年度大会：连接创新与影响
Hannah K Jackson,Naveed Akbar,Nick Peake et al.
Hannah K Jackson et al.
In December 2024, the United Kingdom Society for Extracellular Vesicles (UKEV) held its annual forum in Newcastle upon Tyne, marking 11 years since its founding. UKEV Forum 2024 brought together over 230 participants from the UK and abroad ...
Tear-derived extracellular vesicles as diagnostic biomarkers for ocular and neurodegenerative diseases: opportunities and challenges [0.03%]
泪源性细胞外囊泡作为眼部和神经退行性疾病诊断生物标志物的机会与挑战
Marta Sanroque-Muñoz,Sergio G Garcia,Linrong Pan et al.
Marta Sanroque-Muñoz et al.
In recent years, the prevalence of ocular diseases has increased considerably. However, timely diagnosis and treatment are hampered by the challenge of early detection since symptoms often appear in advanced stages. Emerging research highli...
Extracellular vesicles: cargo loading, degradation and secretory pathways, and their intersection with autophagy [0.03%]
细胞外囊泡：装载、降解和分泌途径及其与自噬的相互作用
Jinzhe Ju,Sophie M L Neuen,Marc van Zandvoort et al.
Jinzhe Ju et al.
Extracellular vesicles (EVs) are secreted by nearly all cell types and fulfil a crucial role in intercellular communication by transporting diverse cargo, including enzymes, mRNA, growth factors, chemokines, and cytokines. Although EVs were...
Reproducibility and transparency: why following MISEV guidelines is beneficial for the studies on EVs and brain barriers [0.03%]
可重复性和透明度：为何遵循MISEV指南对研究EV和脑屏障有益
Julien Saint-Pol
Julien Saint-Pol
A new hope for pulmonary hypoplasia: amniotic fluid stem cell extracellular vesicles? [0.03%]
肺发育不全的新希望：羊水干细胞外泌体？
Ishara Atukorala,Lisa Hui
Ishara Atukorala
In a recent study, Antounians and colleagues (2024) investigated the potential of amniotic fluid stem cell-derived extracellular vesicles (AFSC-EVs) as a therapeutic intervention for pulmonary hypoplasia resulting from congenital diaphragma...
Ying Gao,Tiebang Kang
Ying Gao
Blebbisomes represent a newly identified class of large extracellular vesicles (EVs) that exhibit unique functional capabilities in intercellular communication. Beyond their motility, blebbisomes engage in complex vesicle trafficking functi...
Hui Lu,Jin Zhang,Tianzhuo Shen et al.
Hui Lu et al.
Extracellular vesicles (EVs) are a type of cell-released phospholipid bilayer nanoscale carrier. However, research on EVs encounters several challenges, such as their heterogeneity, the complexities associated with their isolation and ident...
Benjamin I Burke,John J McCarthy,Ahmed Ismaeel
Benjamin I Burke
A recent study from Liu et al. described the role of skeletal muscle-derived extracellular vesicles in promoting liver fibrosis as an outcome of chronic overtraining in mice. Here, we highlight this work and discuss its implications within ...
Carine de Marcos Lousa
Carine de Marcos Lousa
Lignin is an important component of plant cell walls, providing structural support and defense. Despite extensive research, the mechanisms underlying the transport and polymerization of lignin precursors remain poorly understood. Kankaanpä...
Optimized size exclusion chromatography demonstrates that extracellular vesicles are the key RNA carriers of ALK translocations in non-small cell lung cancer cell line secretome and patient plasma [0.03%]
优化尺寸排除色谱法证明外泌体是ALK重排非小细胞肺癌细胞系分泌组和患者血浆中RNA的关键载体
Beatriz Benayas,Estela Sánchez-Herrero,Lucía Robado de Lope et al.
Beatriz Benayas et al.
Aim: Identification of ALK fusions in non-small cell lung cancer (NSCLC) is key to determining eligibility for treatment with ALK inhibitors that markedly improve patients' quality of life and survival outcomes. Circulating RNA, associated ...