Extracellular vesicles in malignant and normal B lymphocyte growth and development [0.03%]
恶性B淋巴细胞和正常B淋巴细胞的生长发育中的胞外囊泡功能研究
Kaitlyn E Mayne,Rashid Jafardoust,Hong-Dien Phan et al.
Kaitlyn E Mayne et al.
Extracellular vesicles (EVs) are central mediators of intercellular communication in both healthy and malignant states. In normal B lymphocyte (cell) biology, EVs derived from B cells, mast cells, T cells, and mesenchymal stromal cells regu...
Adipose-derived stem cell extracellular vesicles attenuate liver fibrosis via restoration of gut barrier function and modulation of gut microbiota [0.03%]
脂肪来源干细胞外泌体通过恢复肠道屏障功能和调节肠道菌群来缓解肝纤维化
Baitong Wu,Jingyi Guo,Jian Wang et al.
Baitong Wu et al.
Aim: Liver fibrosis (LF) is a major pathological stage that may progress to end-stage chronic liver injury but currently lacks effective treatment strategies. Previous studies have shown that adipose-derived stem cell extracellular vesicles...
Special delivery - extracellular vesicles released by commensal gut bacteria deliver bioactive protein to distal organs [0.03%]
特殊投递：共生肠道菌释放的细胞间囊泡向远端器官递送生物活性蛋白
Emily J Jones,Aimee Parker,Rokas Juodeikis et al.
Emily J Jones et al.
Aim: This study aims to investigate how the gut microbiota communicates with the host via bacterial extracellular vesicles (BEVs), given that direct contact between microbes and the healthy intestinal epithelium is prevented by a sterile mu...
Assessment of the reproducibility of bacterial membrane vesicle isolation and characterization [0.03%]
细菌膜囊泡分离和表征的可重复性评估
Jari Verbunt,Johan Jocken,Emanuel Canfora et al.
Jari Verbunt et al.
Aim: This study aimed to evaluate the reproducibility of the isolation and characterization of feces-derived bacterial membrane vesicles. Methods: Human fecal samples (n = 12) stored at -80 °C were thawed, sampled, and then refrozen. From ...
Extracellular vesicle-associated lncRNA LYPLAL1-DT mediates endothelial-cancer cell communication, promoting small cell lung cancer progression [0.03%]
细胞外囊泡相关长链非编码RNA LYPLAL1-DT介导内皮细胞-癌细胞通讯促进小细胞肺癌进展
Xing Zhang,Caijiao Hu,Zhihui Li et al.
Xing Zhang et al.
Aim: Representing about 15% of lung cancers, small cell lung cancer (SCLC) is an extremely aggressive disease characterized by rapid growth and early spread, leading to dismal clinical outcomes. In this study, we aimed to investigate the du...
Impact of autologous blood transfusions on surface marker and microRNA profiles of urinary extracellular vesicles [0.03%]
同种自体输血对尿液细胞外囊泡表面标志物和微小RNAs的影响
Veronika Mussack,Michael W Pfaffl
Veronika Mussack
Aim: Autologous blood transfusions (ABT), especially those involving stored erythrocyte concentrates (ECs), are known to be misused as performance enhancers in recreational and competitive athletes. EC storage not only increases the release...
Enis Kostallari
Enis Kostallari
The crosstalk between the skeletal muscles and the liver is receiving growing attention, as patients with chronic liver disease often develop a loss of skeletal muscle mass. In these patients, particularly those with metabolic dysfunction-a...
Overview of extracellular vesicles as biomarkers and therapeutic tools in pediatric diseases: focus on the gut-lung axis [0.03%]
外泌体作为儿科疾病生物标志物和治疗工具的概述：重点关注肠肺轴
Paola Bisaccia,Alice Zaramella,Agner Henrique Dorigo Hochuli et al.
Paola Bisaccia et al.
Although anatomically separate, the gut and lungs are interconnected through intricate pathways involving their respective microbiota, supporting the concept of a gut-lung axis. In the pediatric field, devastating intestinal pathologies suc...
5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer [0.03%]
血浆细胞外囊泡DNA 5-羟甲基胞嘧啶表观遗传标志物用于胃癌癌前病变诊断的价值研究
Haoyu Chen,Tianyu Gao,Hangyu Chen et al.
Haoyu Chen et al.
Aim: Precancerous lesions of gastric cancer (PLGC) represent a critical window for prevention. Developing non-invasive tools that can reliably detect these lesions is therefore a prerequisite for lowering gastric-cancer incidence. Recent wo...
Extracellular vesicles in bone aging: therapeutic strategies and applications [0.03%]
外泌体与骨衰老：治疗策略及应用前景
Lin Tang,Peng Wang,Shihao Sheng et al.
Lin Tang et al.
As global aging intensifies, the issue of bone aging has become increasingly prominent. Osteoporosis and osteoarthritis, which are common complications of bone aging, significantly impair patients' quality of life due to their high prevalen...