Overview of extracellular vesicles as biomarkers and therapeutic tools in pediatric diseases: focus on the gut-lung axis [0.03%]
外泌体作为儿科疾病生物标志物和治疗工具的概述：重点关注肠肺轴
Paola Bisaccia,Alice Zaramella,Agner Henrique Dorigo Hochuli et al.
Paola Bisaccia et al.
Although anatomically separate, the gut and lungs are interconnected through intricate pathways involving their respective microbiota, supporting the concept of a gut-lung axis. In the pediatric field, devastating intestinal pathologies suc...
5-hydroxymethylcytosine signature in plasma extracellular vesicle DNA as a diagnostic molecular biomarker for precancerous lesions of gastric cancer [0.03%]
血浆细胞外囊泡DNA 5-羟甲基胞嘧啶表观遗传标志物用于胃癌癌前病变诊断的价值研究
Haoyu Chen,Tianyu Gao,Hangyu Chen et al.
Haoyu Chen et al.
Aim: Precancerous lesions of gastric cancer (PLGC) represent a critical window for prevention. Developing non-invasive tools that can reliably detect these lesions is therefore a prerequisite for lowering gastric-cancer incidence. Recent wo...
Extracellular vesicles in bone aging: therapeutic strategies and applications [0.03%]
外泌体与骨衰老：治疗策略及应用前景
Lin Tang,Peng Wang,Shihao Sheng et al.
Lin Tang et al.
As global aging intensifies, the issue of bone aging has become increasingly prominent. Osteoporosis and osteoarthritis, which are common complications of bone aging, significantly impair patients' quality of life due to their high prevalen...
CD9+ and CD82+ extracellular vesicles in synovial fluid differentiate aseptic from septic endoprosthesis loosening [0.03%]
CD9和CD82阳性细胞外囊泡鉴别无菌性与细菌性人工关节置换术后假体松动
Tobias Tertel,Vera Rebmann,Charlotte Bielefeld et al.
Tobias Tertel et al.
Aim: Extracellular vesicles (EVs) hold great promise as emerging biomarkers for a variety of diseases. However, their clinical application is still hindered by complex and time-consuming isolation procedures. A clinically relevant scenario ...
Enrico Ragni,Enrico Lucarelli,Stefano Grolli et al.
Enrico Ragni et al.
Extracellular vesicles as vehicles for small non-coding RNA therapeutics: standardization challenges for clinical translation [0.03%]
作为小非编码RNA治疗载体的细胞外囊泡：临床转化的标准挑战
Lucrezia Luisotti,Lorenzo Germelli,Rebecca Piccarducci et al.
Lucrezia Luisotti et al.
Aim: Extracellular vesicles (EVs) have emerged as promising vehicles for the delivery of small non-coding RNAs (sncRNAs); however, their clinical translation is hindered by the lack of standardized manufacturing methods, RNA loading protoco...
Enrico Ragni,Rita Romani,Valentina Grespi et al.
Enrico Ragni et al.
The GISM Annual Meeting 2025 convened experts in regenerative medicine and nanomedicine to discuss recent advances in mesenchymal stromal/stem cell (MSC) research and extracellular vesicle (EV) technologies. The meeting emphasized novel str...
The 4th annual American Society for Intercellular Communication (ASIC) meeting, 2024 conference report [0.03%]
2024年美国细胞间通讯协会(ASIC)第四次年度会议报告
Ashley E Russell,Aurelio Lorico
Ashley E Russell
Microfluidic devices for on-chip quantification of extracellular vesicles and associated biomarkers [0.03%]
片上量化细胞外囊泡及其相关生物标志物的微流体装置
Víctor Calero,Carlos Honrado,Alar Ainla et al.
Víctor Calero et al.
In the past decade, extracellular vesicles (EVs) have gained increasing attention in biomedical research. These membrane-bound particles are naturally secreted by cells under both physiological and pathological conditions, and they exhibit ...
Stem-cell-derived extracellular vesicles in neurodegeneration and neuroaging: therapeutic potential and challenges [0.03%]
干细胞来源的细胞外囊泡在神经退行性和神经老化中的治疗潜力与挑战
Mohit Kumar,Sudipta Ray,Susmita Sil
Mohit Kumar
Neuroaging is a complex biological process in which the brain undergoes progressive functional decline marked by synaptic loss, neuroinflammation, and cognitive decline. At the molecular and cellular level, aging is driven by multiple inter...