Tahlia I Smith,Ashley E Russell
Tahlia I Smith
Extracellular vesicles (EVs) are small, lipid-bound packages that are secreted by all cell types and have been implicated in many diseases, such as cancer and neurodegenerative disorders. Though limited, an exciting new area of EV research ...
Robert H Eibl,Markus Schneemann
Robert H Eibl
Translational research of liquid biopsy is just at the edge of routine clinical application: an emerging validity of circulating tumor DNA (ctDNA) tests suggests its use for earlier cancer detection and better monitoring of minimal residual...
Expanded knowledge of cell-free DNA biology: potential to broaden the clinical utility [0.03%]
关于细胞游离DNA生物学的新认知：潜在的临床应用价值拓展
Huiwen Che,Kate Stanley,Tatjana Jatsenko et al.
Huiwen Che et al.
Noninvasive sampling of an individual's body fluids is an easy means to capture circulating cell-free DNA (cfDNA). These small fragments of DNA carry information on the contributing cell's genome, epigenome, and nuclease content. Analysis o...
Meeting Abstracts of the first meeting of the American Society for Intercellular Communication 2021 [0.03%]
2021年美国细胞通讯学会首次会议摘要集
Gurudutt Pendyala,Ashley E Russell,Shilpa Buch et al.
Gurudutt Pendyala et al.
Towards responsible ctDNA-based multi-cancer screening: a preliminary exploration and discussion of ethically relevant aspects [0.03%]
基于ctDNA的多癌筛查向负责任过渡：伦理相关内容的初步探索与讨论
Wybo Dondorp,Guido de Wert
Wybo Dondorp
While testing for easily accessible biomarkers in the circulation ("liquid biopsy") has found its way to clinical cancer care, a further expected development is its use as a "universal" early detection test in population screening for cance...
Leveraging biomimetic synthesis strategy for next-generation dendritic cell nanovaccines [0.03%]
利用生物合成策略开发下一代树突细胞纳米疫苗
Yutian Xia,Jianzhong Zhang
Yutian Xia
The activation of CD8+ cytotoxic T-lymphocytes (CTLs) plays the central role in cancer immunotherapy, which depends on the efficient recognition of peptide-major histocompatibility complex (pMHC) by the T cell receptor (TCR) for the first s...
A kaleidoscopic view of extracellular vesicles in lysosomal storage disorders [0.03%]
溶酶体贮积病中细胞外囊泡的 kaleidoscopic 视角
Charlotte V Hegeman,Olivier G de Jong,Magdalena J Lorenowicz
Charlotte V Hegeman
Extracellular vesicles (EVs) are a heterogeneous population of stable lipid membrane particles that play a critical role in the regulation of numerous physiological and pathological processes. EV cargo, which includes lipids, proteins, and ...
Towards extracellular vesicle delivery systems for tissue regeneration: material design at the molecular level [0.03%]
面向组织再生的细胞外囊泡递送系统：分子水平的材料设计
Ao Chen,Hengli Tian,Nana Yang et al.
Ao Chen et al.
The discovery and development of extracellular vesicles in tissue engineering have shown great potential for tissue regenerative therapies. However, their vesicle nature requires dosage-dependent administration and efficient interactions wi...
Xi Hu,Spencer C Ding,Peiyong Jiang
Xi Hu
Analysis of cell-free DNA (cfDNA) in the blood has shown promise for monitoring a variety of biological processes. Plasma cfDNA is a mixture comprising DNA molecules released from various bodily tissues, mediated by characteristic DNA fragm...
Yoke Peng Loh
Yoke Peng Loh