Towards extracellular vesicle delivery systems for tissue regeneration: material design at the molecular level [0.03%]
面向组织再生的细胞外囊泡递送系统：分子水平的材料设计
Ao Chen,Hengli Tian,Nana Yang et al.
Ao Chen et al.
The discovery and development of extracellular vesicles in tissue engineering have shown great potential for tissue regenerative therapies. However, their vesicle nature requires dosage-dependent administration and efficient interactions wi...
Xi Hu,Spencer C Ding,Peiyong Jiang
Xi Hu
Analysis of cell-free DNA (cfDNA) in the blood has shown promise for monitoring a variety of biological processes. Plasma cfDNA is a mixture comprising DNA molecules released from various bodily tissues, mediated by characteristic DNA fragm...
Yoke Peng Loh
Yoke Peng Loh
The multifaceted roles of extracellular vesicles for therapeutic intervention with non-Hodgkin lymphoma [0.03%]
外泌体在非霍奇金淋巴瘤治疗干预中的多面手角色
Arthur A Lee,Andrew K Godwin,Haitham Abdelhakim
Arthur A Lee
Extracellular vesicles (EVs) contribute to the development of cancer in various ways. Non-Hodgkin lymphoma (NHL) is a cancer of mature lymphocytes and the most common hematological malignancy globally. The most common form of NHL, diffuse l...
Delivery of miR-214 via extracellular vesicles downregulates Xbp1 expression and pro-inflammatory cytokine genes in macrophages [0.03%]
miR-214介导的细胞外囊泡通过下调未折叠蛋白反应和炎症因子抑制巨噬细胞过度活化
Gonzalo Almanza,Stephen Searles,Maurizio Zanetti
Gonzalo Almanza
Aim: Tumor-infiltrating macrophages are tumor-promoting and show activation of the unfolded protein response (UPR). The transcription factor X-box binding protein 1 (XBP1) is a conserved element of the UPR. Upon activatio...
Mitochondria-derived vesicles: potential nano-batteries to recharge the cellular powerhouse [0.03%]
线粒体衍生囊泡：细胞能量工厂的潜在纳米电池
Shalini Mishra,Gagan Deep
Shalini Mishra
Mitochondria dysfunction is increasingly recognized as a critical factor in various pathogenic processes. The mechanism governing mitochondrial quality control serves as an adaptive response, ensuring the preservation of mitochondrial morph...