Research on exosomes in cancer multidrug resistance and clinical translation [0.03%]
外泌体在肿瘤耐药和临床转化中的研究进展
Wenxin Zhang,Mengyuan He,Xiaoli Cheng et al.
Wenxin Zhang et al.
Multidrug resistance (MDR) is a major clinical challenge that limits the efficacy of multiple cancer treatment modalities, including chemotherapy, targeted therapy, immunotherapy, monoclonal antibody therapy, and antibody-drug conjugates. I...
Biological properties and potential pathogenic mechanisms of oral bacterial-derived extracellular vesicles in oral and systemic diseases [0.03%]
口腔细菌源性外泌体的生物学性质及其在口腔和系统性疾病中的潜在致病机制
Xumeng Du,Shiyin Xu,Xiaolei Zhou et al.
Xumeng Du et al.
This review summarizes the biological characteristics of oral bacterial extracellular vesicles (O-BEVs) and their proposed roles in disease pathogenesis. As nanosized lipid bilayer structures secreted by oral bacteria, O-BEVs encapsulate vi...
Neuropilin-1 enriched mesenchymal stem cell derived-exosomes alleviate vascular hyperpermeability in acute lung injury [0.03%]
神经纤毛蛋白-1富集的间充质干细胞源外泌体通过减少急性肺损伤中的血管高通透性发挥保护作用
Qinyi Deng,Yifan Lu,Linyan Yuan et al.
Qinyi Deng et al.
Aim: Mesenchymal stem cells (MSCs) have shown therapeutic potential in acute lung injury (ALI); however, the key functional components and their roles in regulating pulmonary vascular endothelial permeability remain unclear. This study aime...
Advances in microbial extracellular vesicles: synthetic biology platforms and medical applications [0.03%]
微生物外泌体研究进展：合成生物学平台与医学应用
Zi-Yue-Er Tang,Xin-Lu Yang,Yan-Wen Zhou et al.
Zi-Yue-Er Tang et al.
Extracellular vesicles (EVs), typically ranging from 20 to 400 nanometers in diameter, are membrane-bound structures released into the extracellular environment by bacteria via specific secretion mechanisms. Consequently, these vesicles pla...
Comparison of extracellular vesicle isolation methods reveals method-dependent protein and miRNA profiles in saliva [0.03%]
不同方法提取的口腔液外泌体蛋白质及miRNA特征分析
Elodie Simphor,Jérémy Boulestreau,Romane Marchal et al.
Elodie Simphor et al.
Aim: Salivary extracellular vesicles (EVs) are promising non-invasive biomarkers for disease diagnosis and monitoring, reflecting both systemic and local physiological states. However, the diversity of EV isolation protocols and the possibi...
Amniotic extracellular vesicles' effect on equine endometrial cells challenged with LPS: a proteomic analysis [0.03%]
胎盘外泌体对脂多糖刺激的马子宫内膜细胞的作用：蛋白质组学分析
Giulia Gaspari,Alessio Soggiu,Paola Gagni et al.
Giulia Gaspari et al.
Aim: A balanced uterine environment is crucial for the positive outcome of a pregnancy. Any alteration of its physiological status could affect embryo-maternal crosstalk and impair the mare fertility, as occurs in endometrial inflammatory c...
Extracellular vesicles as mediators of prostatic diseases: connecting function to diagnostic and therapeutic applications [0.03%]
外泌体作为前列腺疾病介质：连接功能与诊断和治疗应用
Julie Bishara,Morolake Morakinyo,Sharanjot Saini
Julie Bishara
Diseases of the prostate gland, including benign prostatic hyperplasia (BPH) and prostate cancer (PCa), affect a significant proportion of men worldwide. The incidence of these diseases increases with advancing age decreased quality of life...
Microbial extracellular vesicles in the lung: friends in health, agents in disease [0.03%]
肺部微生物外泌体：健康时的朋友，疾病中的使者
Marta Pagnini,Maria Conti,Giorgia Puddu et al.
Marta Pagnini et al.
Microbial extracellular vesicles (mEVs) are emerging as key mediators at the host-microbe interface in the lung, playing a remarkable dual role as both pathogenic drivers and therapeutic modulators. These nano-sized, membrane-bound structur...
Rehmannia glutinosa nanovesicles protect cardiomyoblasts from oxidative injury [0.03%]
地黄纳米囊泡通过改善线粒体功能保护心肌细胞抗氧化损伤
Huilan Fan,Shuang Zhao,Yunfeng Di et al.
Huilan Fan et al.
Aim: Oxidative stress is a key driver of cardiovascular disease, underscoring the need for safe and effective antioxidant therapies. This study aims to evaluate the cardioprotective potential of plant-derived nanovesicles (PDNVs) derived fr...