Strategies to functionalize extracellular vesicles against HER2 for anticancer activity [0.03%]
工程化外泌体特异性识别HER2阳性肿瘤的策略研究
Elena Gurrieri,Vito Giuseppe D&#x;Agostino
Elena Gurrieri
Cell-secreted extracellular vesicles (EVs) are membranous particles highly heterogeneous in size and molecular cargo. Comprehensively, released EV sub-populations can show a wide range and selection of different protein, RNA, and lipid spec...
Engineered mammalian and bacterial extracellular vesicles as promising nanocarriers for targeted therapy [0.03%]
工程化的哺乳动物和细菌外泌体作为有前景的靶向治疗纳米载体
Han Liu,Zhen Geng,Jiacan Su
Han Liu
Extracellular vesicles (EVs), which are nanocarriers with phospholipid bilayer structures released by most cells, play a key role in regulating physiological and pathological processes. EVs have been investigated due to their loading capaci...
Summary report of the 1st MOVE symposium in Málaga from 24-27th October 2023 - Foster the European mobility for young scientists in extracellular vesicles research [0.03%]
2023年10月24日至27日在马拉加举行的首届MOVE研讨会总结报告——促进欧洲外泌体研究青年科学家的流动性
Mia S C Yu,Tanja V Edelbacher,Christian Grätz et al.
Mia S C Yu et al.
Uma Maheswari Deshetty,Susmita Sil,Shilpa Buch
Uma Maheswari Deshetty
This commentary provides an in-depth analysis and perspective on the pioneering research article titled 'Extracellular Vesicle-Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart'. The original study explores th...
Contribution of extracellular vesicles to neuroinflammation and cognitive and motor deficits in hyperammonemia and hepatic encephalopathy [0.03%]
外泌体在高血氨和肝性脑病神经炎症及认知和运动功能障碍中的作用
Paula Izquierdo-Altarejos,Vicente Felipo
Paula Izquierdo-Altarejos
Cirrhotic patients can present hepatic encephalopathy (HE), showing motor and cognitive deficits. Hyperammonemia and peripheral inflammation are known to induce neuroinflammation and alter neurotransmission, which finally induces neurologic...
The isolation of VCAM-1+ endothelial cell-derived extracellular vesicles using microfluidics [0.03%]
利用微流控技术分离VCAM-1阳性内皮细胞源外泌体
Naveed Akbar,Evelyn Grace Luciani,Raheel Ahmad et al.
Naveed Akbar et al.
Background: Vascular cell adhesion molecule-1 (VCAM-1+) endothelial cell-derived extracellular vesicles (EC-EVs) are augmented in cardiovascular disease, where they can signal the deployment of immune cells from the splenic reserve. Endothe...
Mesenchymal stem cell-derived extracellular vesicles for human diseases [0.03%]
人 mesenchymal干细胞源外泌体及其在疾病治疗中的应用研究进展
Xiaofang Zhang,Xiaofang Che,Sibo Zhang et al.
Xiaofang Zhang et al.
Stem cell therapy is a novel approach for treating various severe and intractable diseases, including autoimmune disorders, organ transplants, tumors, and neurodegenerative diseases. Nevertheless, the extensive utilization of stem cells is ...
Impact of hypoxia on the molecular content of glioblastoma-derived exosomes [0.03%]
缺氧对胶质母细胞瘤来源的外泌体分子含量的影响
Simona Di Giulio,Elisabetta Carata,Marco Muci et al.
Simona Di Giulio et al.
Hypoxia is a pathologic condition characterized by a tissue oxygen deficiency due to either decreased oxygen intake from outside and/or disruption of oxygen utilization in cells. This condition may arise when the oxygen demand exceeds its s...
A comparative analysis of small extracellular vesicle (sEV) micro-RNA (miRNA) isolation and sequencing procedures in blood plasma samples [0.03%]
血液血浆样本中小型细胞外囊泡（sEV）microRNA（miRNA）分离和测序程序的比较分析
Pevindu Abeysinghe,Natalie Turner,Murray D Mitchell
Pevindu Abeysinghe
Aims: Analysis of miRNA (18-23nt) encapsulated in small extracellular vesicles (sEVs) (diameter ~30-200 nm) is critical in understanding the diagnostic and therapeutic value of sEV miRNA. However, various sEV enrichment t...
Harnessing genetically engineered cell membrane-derived vesicles as biotherapeutics [0.03%]
利用基因工程细胞膜衍生囊泡作为生物治疗药物
Xiaohong Li,Yuting Wei,Zhirang Zhang et al.
Xiaohong Li et al.
Cell membrane-derived vesicles (CMVs) are particles generated from living cells, including extracellular vesicles (EVs) and artificial extracellular vesicles (aEVs) prepared from cell membranes. CMVs possess considerable potential in drug d...