Potential clinical applications of extracellular vesicles in pancreatic cancer: exploring untapped opportunities from biomarkers to novel therapeutic approaches [0.03%]
外泌体在胰腺癌临床应用的潜在价值：从生物标志物到新型治疗策略的探索
Jose Manuel Sanchez-Manas,Natalia Perez de Gracia,Sonia Perales et al.
Jose Manuel Sanchez-Manas et al.
Pancreatic cancer is a highly lethal and metastatic malignancy, mainly because it often remains undetected until advanced stages due to the limitations of current diagnostic methods, rendering currently available therapies ineffective. Ther...
Hollow fiber bioreactor allows sustained production of immortalized mesenchymal stromal cell-derived extracellular vesicles [0.03%]
中空纤维生物反应器允许源自间充质基质细胞的免疫永生化细胞衍生的细胞外囊泡持续生产
Sergio G Garcia,Marta Sanroque-Muñoz,Marta Clos-Sansalvador et al.
Sergio G Garcia et al.
Aim: Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) have been reported to hold great potential as cell-free therapies due to their low immunogenicity and minimal toxicity. However, the large doses of MSC-EVs that are requ...
Impact of donor pool size on the variability of platelet lysate-derived extracellular vesicles for regenerative medicine [0.03%]
供体池大小对再生医学中血小板溶解物衍生的细胞外囊泡变异性的影响力
Andreu Miquel Amengual-Tugores,Carmen Ráez-Meseguer,Maria Antònia Forteza-Genestra et al.
Andreu Miquel Amengual-Tugores et al.
Aim: The objective of the present study was to determine the variability of platelet lysate-derived extracellular vesicles (pEV), in terms of characteristics and functionality through wound healing assays, when isolated either from platelet...
Synovial fluid extracellular vesicles as arthritis biomarkers: the added value of lipid-profiling and integrated omics [0.03%]
滑膜液外泌体作为关节炎生物标志物：脂质组学和整合组学的附加价值
Laura Varela,Chris H A van de Lest,P René van Weeren et al.
Laura Varela et al.
Arthritis, a diverse group of inflammatory joint disorders, poses great challenges in early diagnosis and targeted treatment. Timely intervention is imperative, yet conventional diagnostic methods are not able to detect subtle early symptom...
Y Peng Loh
Y Peng Loh
Platform technologies and human cell lines for the production of therapeutic exosomes [0.03%]
用于治疗性外泌体生产的平台技术和人细胞系
Jiyoon Kim,Yonghee Song,Cheol Hyoung Park et al.
Jiyoon Kim et al.
Exosomes are extracellular vesicles secreted by most cell types and represent various biological properties depending on their producing cells. They are also known to be important mediators of intercellular communication. Recent data sugges...
Mesenchymal stem cell-derived extracellular vesicles for cell-free therapy of ocular diseases [0.03%]
间充质干细胞衍生的细胞外囊泡在眼科细胞治疗中的应用研究进展
Xiaoling Liu,Liang Hu,Fei Liu
Xiaoling Liu
Mesenchymal stem cells-derived extracellular vesicles (MSC-EVs) have noticeably attracted clinicians' attention in treating ocular diseases. As the paracrine factor of MSCs and an alternative for cell-free therapies, MSC-EVs can be convenie...
Ying Zhang,Hang Yin
Ying Zhang
Extracellular vesicles (EVs) have been regarded as influential intracellular delivering parcels that possess tremendous potential because of their strict and complex secretion regulation processes. However, traditional detection methods can...
New insights of engineering plant exosome-like nanovesicles as a nanoplatform for therapeutics and drug delivery [0.03%]
工程化植物外泌体样纳米囊泡作为治疗和药物递送的纳米平台的新见解
Shafiu A Umar Shinge,Yin Xiao,Jiang Xia et al.
Shafiu A Umar Shinge et al.
Plant exosome-like nanovesicles (PELNVs) are membrane-encapsulated nanostructures released from cells into their surroundings. PELNVs have an important role in intercellular and interspecies communication in all three domains of life. They ...