The unexpected PD-L1 suppression function of celery-derived extracellular vesicles improves lung cancer chemotherapy efficacy [0.03%]
意外发现的芹菜来源细胞外囊泡PD-L1抑制功能可增强肺癌化疗效果
Xin Lu,Ziwen Yu,Junjun Wang et al.
Xin Lu et al.
Aim: The article explores celery-derived extracellular vesicles (CDEVs), characterized by high cellular uptake, low immunogenicity, and high stability, as a therapeutic strategy for antitumor nanomedicines. Methods: The methods employed in ...
Engineered extracellular vesicles as "supply vehicles" to alleviate type 1 diabetes [0.03%]
工程化的细胞外囊泡作为“供应车”来缓解1型糖尿病
Fei Wang,Zhenhua Li
Fei Wang
Recent findings have indicated that the deficiency of inhibitory programmed cell death ligand 1 (PD-L1) and galectin-9 (Gal-9) in pancreatic β-cells is associated with the progression of type 1 diabetes (T1D). This suggests that exogenous ...
The 3rd annual American Society for Intercellular Communication (ASIC) meeting, 2023 conference report [0.03%]
2023年美国细胞通讯协会年会会议报告
Ashley E Russell,Aurelio Lorico
Ashley E Russell
Extracellular vesicles of Lactiplantibacillus plantarum PCM 2675 and Lacticaseibacillus rhamnosus PCM 489: an introductory characteristic [0.03%]
肠膜明串珠菌PCM 2675和鼠李糖乳杆菌PCM 489的胞外囊泡：初步特征分析
Katarzyna Kowalik,Kamila Kulig,Elzbieta Karnas et al.
Katarzyna Kowalik et al.
Aim: Extracellular vesicles (EVs) are involved in intercellular and interkingdom communication in the complex communities that constitute the niche-specific microbiome of the colonized host. Therefore, studying the structure and content of ...
The role of cancer cell-released extracellular vesicles: have we become closer to cancer pain treatment? [0.03%]
癌细胞释放的细胞外囊泡的作用：我们是否已经接近癌症疼痛治疗？
Iryna A Khasabova,Sergey G Khasabov,Donald A Simone
Iryna A Khasabova
The effective management of cancer pain continues to be a challenge because of our limited understanding of cancer pain mechanisms and, in particular, how cancer cells interact with neurons to produce pain. In a study published in Pain, Iny...
Extracellular vesicles as a promising biomarker resource in liquid biopsy for cancer [0.03%]
外泌体有望成为癌症液体活检中的生物标志物资源
Takaaki Tamura,Yusuke Yoshioka,Shinichi Sakamoto et al.
Takaaki Tamura et al.
Liquid biopsy is a minimally invasive biopsy method that uses molecules in body fluids as biomarkers, and it has attracted attention as a new cancer therapy tool. Liquid biopsy has considerable clinical application potential, such as in ear...
Electrochemical detection of extracellular vesicles for early diagnosis: a focus on disease biomarker analysis [0.03%]
用于早期诊断的体外囊泡的电化学检测：着重于疾病生物标志物分析
Jintao Zheng,Runzhi Zhou,Bing Wang et al.
Jintao Zheng et al.
This review article presents a detailed examination of the integral role that electrochemical detection of extracellular vesicles (EVs) plays, particularly focusing on the potential application for early disease diagnostics through EVs biom...
Lotte Di Niro,Amber C Linders,Thomas Glynn et al.
Lotte Di Niro et al.
Dysregulated intercellular communication is a key feature driving cancer progression. Recently, extracellular vesicles (EVs) have added a new channel to this dense communication network. Despite solid evidence that EVs are central mediators...
Cargo exchange between human and bacterial extracellular vesicles in gestational tissues: a new paradigm in communication and immune development [0.03%]
人和细菌细胞外囊泡在妊娠组织中的物质交换：通讯及免疫发育的新范式
Emmanuel Amabebe,Awanit Kumar,Madhuri Tatiparthy et al.
Emmanuel Amabebe et al.
Host-bacteria and bacteria-bacteria interactions can be facilitated by extracellular vesicles (EVs) secreted by both human and bacterial cells. Human and bacterial EVs (BEVs) propagate and transfer immunogenic cargos that may elicit immune ...
Which casein micelle removal method is suitable for studies of human milk extracellular vesicles? A systematic comparison of four different treatments for casein depletion before extracellular vesicle isolation from human milk [0.03%]
四种去除酪蛋白方法对人乳外泌体分离影响的系统比较研究
Hatice Cetinkaya,Supasek Kongsomros,Laurie Nommsen-Rivers et al.
Hatice Cetinkaya et al.
Aim: This study aimed to systematically compare four casein micelle removal methods on the particle and protein characteristics of the isolated human milk EVs. Methods: The defatted milk was treated with 1% sodium citrate, 20 mM ethylenedia...