Quadruplex Bioactive FAND for Treating Acute Liver Failure Induced by Acetaminophen or Hepatectomy [0.03%]
用于治疗由乙酰氨基酚或肝切除引起的急性肝衰竭的四联活性FAND疗法
Meng Sun,Fang Fang,Juan Liu et al.
Meng Sun et al.
Acute liver failure (ALF), characterized by severe hepatocyte necrosis with a high mortality rate, remains a major global health challenge. However, there are currently no effective drug options for the clinical treatment of ALF. Herein, in...
A High-Efficiency Yet Sustainable Fresh-Keeping Strategy Inspired by Calyx of Physalis peruviana [0.03%]
仿番木瓜萼片高效低耗保鲜策略
Yue Zhao,Chengbang Lu,Xiaopeng Bai et al.
Yue Zhao et al.
To address the dual challenges of foodborne illness and plastic pollution, we present a sprayable, calyx-inspired food wrap engineered for safety and sustainability. Utilizing handheld electrospraying, zeolite-doped polycaprolactone forms a...
Qiang Ma,Hai-Peng Wang,Yu-Meng Jiang et al.
Qiang Ma et al.
Spontaneous calcium (Ca2+) waves play a critical role as internal stimuli in the early developing auditory system before the onset of sensory experiences. However, neither the spatiotemporal control of spontaneous Ca2+ waves nor their impac...
Customizing 3D Hierarchically Macroporous Covalent Organic Framework Superstructures for Improved Biosensing Interface in Highly-Sensitive Electrochemical Biosensors [0.03%]
用于高性能电化学生物传感器的分级三维共价有机框架超结构及其优异的生物传感界面性能
Wenbo Wei,Sheng-Hua Zhou,Dong-Dong Ma et al.
Wenbo Wei et al.
The construction of an optimized biosensing interface is critically important for electrochemical biosensing. Herein, we achieve the controllable construction of macroporous covalent organic framework (COF) nanostructures through a template...
Elimination of Fusobacterium nucleatum With Biomimetic Nanoparticles to Reverse Tumor Immunosuppression and Enhance Colorectal Cancer Therapy [0.03%]
利用仿生纳米颗粒清除核梭杆菌以逆转肿瘤免疫抑制并增强结直肠癌治疗效力
Mengting Zhou,Jiahao Du,Cheng Li et al.
Mengting Zhou et al.
Tumor-associated microbes like Fusobacterium nucleatum (F. nucleatum) critically contribute to immunosuppression and hinder cancer therapy. To overcome this challenge, we developed a microbe-targeted immune reprogramming strategy utilizing ...
An Ocular Surface-Targeting Nucleic Acid Hydrogel for Efficient Dry Eye Disease Treatment [0.03%]
一种有效治疗干眼病的核酸水凝胶眼球表面递送系统
Yuhe Liu,Zimeng Zhai,Yangyang Huang et al.
Yuhe Liu et al.
Dry eye disease (DED) is a prevalent disorder affecting millions worldwide, fueled by both the aging population and extensive use of electronic devices. Yet, current treatments for moderate-to-severe DED fail to fully meet the clinical need...
Antibacterial Hydrogel Dressing With Ca2+-Dependent Hyaluronidase Responsiveness for Accelerating Wound Healing via On-Demand Release of AIE Photosensitizers [0.03%]
一种基于Ca2+响应的透明质酸酶水凝胶抗菌敷料，用于伤口按需递送聚集诱导发光光敏剂治疗加速创面修复功能
Rongwei Cui,Hao Yang,Miaomiao Kang et al.
Rongwei Cui et al.
Reactive oxygen species (ROS)-assisted photodynamic antibiosis emerges as an effective non-antibiotic way to eradicate bacteria in infected wounds. To minimize the indiscriminate damage of excessive ROS to normal tissues, on-demand release ...
Sufficient Gas and Solvated Ion Transport Assisted Rapid NH3 Detection at Room Temperature Through Bionic Olfactory Fibres [0.03%]
仿生嗅觉纤维中快速氨气溶剂化离子传输及室温检测机制研究
Hongyang Liu,Lingyun Xu,Xiaohan Sun et al.
Hongyang Liu et al.
The human olfactory sensing system, based on ionic signal transmission, is featured with fastness, high efficiency and low energy consumption. However, bionic gas sensing materials exhibit performance limitations compared to materials based...
Recent Progress on Graphitic Carbon Nitride-Based Photocatalysts for Hydrogen Peroxide Synthesis [0.03%]
基于石墨相氮化碳光催化剂生成过氧化氢的最新研究进展
Liangpang Xu,Xixian Nan,Jimmy C Yu
Liangpang Xu
Hydrogen peroxide (H2O2) is an indispensable chemical that is used in many industries. Artificial photosynthesis of H2O2 from oxygen and water has obtained worldwide attention due to the merits of low-cost and sustainability. Graphitic carb...
Matching TGF-β1 Activation With Stress-Responsive Charge-Reversal Hydrogel Microspheres for the Treatment of Osteoarthritis [0.03%]
一种用于治疗骨关节炎的应力响应型电荷反转凝胶微球递送系统以匹配TGF-β1活化水平
Feng Lin,Yiwen Xu,Lei Xiang et al.
Feng Lin et al.
The abnormal activation of transforming growth factor-β1 (TGF-β1) is closely associated with the occurrence and progression of diseases. However, how to make the regulatory means match the pathological mechanical microenvironment-dependen...