Application of CRISPR-Cas System in Human Papillomavirus Detection Using Biosensor Devices and Point-of-Care Technologies [0.03%]
CRISPR-Cas系统在生物传感器设备和即时诊断技术中检测人乳头瘤病毒的应用
Chang He,Yongqi Li,Jinkuan Liu et al.
Chang He et al.
Human papillomavirus (HPV) is the most common virus for genital tract infections. Cervical cancer ranks as the fourth most prevalent cancer globally, with over 99% of cases in women attributed to HPV infection. This infection continues to p...
Noninvasive Quantitative Compression Ultrasound Central Venous Pressure: A Clinical Pilot Study [0.03%]
无创定量压缩超声中心静脉压：临床初步研究
Alex T Jaffe,Roger Pallarès-López,Jeffrey K Raines et al.
Alex T Jaffe et al.
Objective: This is an initial study to validate central venous pressure (CVP) measurements derived from quantitative compression ultrasound (QCU). Impact Statement: This study is the first gold standard invasive validation of CVP estimation...
Graph-Based 3-Dimensional Spatial Gene Neighborhood Networks of Single Cells in Gels and Tissues [0.03%]
基于图形的凝胶和组织中单细胞的三维空间基因邻域网络
Zhou Fang,Kelsey Krusen,Hannah Priest et al.
Zhou Fang et al.
Objective: We developed 3-dimensional spatially resolved gene neighborhood network embedding (3D-spaGNN-E) to find subcellular gene proximity relationships and identify key subcellular motifs in cell-cell communication (CCC). Impact Stateme...
Leveraging Large Language Models for Predicting Postoperative Acute Kidney Injury in Elderly Patients [0.03%]
利用大型语言模型预测老年患者术后急性肾损伤
Hanfei Zhu,Ruojiang Wang,Jiajie Qian et al.
Hanfei Zhu et al.
Objective: The objective of this work is to develop a framework based on large language models (LLMs) to predict postoperative acute kidney injury (AKI) outcomes in elderly patients. Impact Statement: Our study demonstrates that LLMs have t...
Functional Bacterial Cellulose-Based MXene (Ti3C2T x ) Electronic-Skin Patch for Accelerated Healing and Monitoring [0.03%]
用于促进愈合和监测的功能细菌纤维素基MXene(Ti3C2T x) 电子皮肤贴片
Saliha Nur lIhan,Bahar Akyuz Yilmaz,Fatih Ciftci
Saliha Nur lIhan
Objective: This study aims to develop and characterize electroactive hydrogels based on reduced bacterial cellulose (BC) and Ti3C2T x -MXene for their potential application in wound healing and real-time monitoring. Impact Statement: The in...
Biomaterials for Modulating the Immune Microenvironment in Rheumatoid Arthritis [0.03%]
用于调节类风湿关节炎免疫微环境的生物材料
Qiaoxuan Wang,Junzhang Ji,Ding Huang et al.
Qiaoxuan Wang et al.
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease characterized by joint swelling and bone destruction. Despite an incomplete understanding of its genesis, RA is tightly linked to the intricate immunological milieu, in...
Advancing Nanotechnology: Targeting Biofilm-Forming Bacteria with Antimicrobial Peptides [0.03%]
纳米技术的进步：用抗菌肽靶向生物膜形成细菌
Julia Valladares Campos,Janaína Teixeira Costa Pontes,Christian Shleider Carnero Canales et al.
Julia Valladares Campos et al.
Nanotechnology offers innovative solutions for addressing the challenges posed by biofilm-forming bacteria, which are highly resistant to conventional antimicrobial therapies. This review explores the integration of pharmaceutical nanotechn...
Machine Learning Approach to Investigating Macrophage Polarization on Various Titanium Surface Characteristics [0.03%]
机器学习在研究巨噬细胞极化过程中对钛表面不同特性影响中的应用
Changzhong Chen,Zhenhuan Xie,Songyu Yang et al.
Changzhong Chen et al.
Objective: Current laboratory studies on the effect of biomaterial properties on immune reactions are incomplete and based on a single or a few combination features of the biomaterial design. This study utilizes intelligent prediction model...
Direct Redox Sensing of Caffeine Utilizing Zinc-Doped Tin Oxide Nanoparticles as an Electrocatalyst [0.03%]
利用锌掺杂氧化锡纳米颗粒作为电催化剂直接氧化还原检测咖啡因
Gaurav Bhanjana,Ravinder Lamba,Manjit Singh Jadon et al.
Gaurav Bhanjana et al.
Objective: In addition to its positive benefits, caffeine also has harmful consequences. Therefore, it is essential to ascertain its content in various substances. Impact Statement: The present study emphasizes a novel way of quantification...
Jia Hu,Qing Yu,Lei Wang et al.
Jia Hu et al.
Catheter-related infections (CRIs) caused by hospital-acquired microbial infections lead to the failure of treatment and the increase of mortality and morbidity. Surface modifications of the implant catheters have been demonstrated to be ef...