Risk of subsequent self-harm, suicide attempts and suicide following a first hospital-treated self-harm episode among young people: a population-based cohort study [0.03%]
年轻人大规模队列研究：初次住院治疗自我伤害后再次自杀、自杀企图和自我伤害的风险
Thuy-Dung Nguyen,Moa Karemyr,Ralf Kuja-Halkola et al.
Thuy-Dung Nguyen et al.
Background: Self-harm in young people is associated with elevated risks for subsequent self-harm, suicide attempts and suicide, particularly during the first year. Yet the trajectory across sex, age and self-harm methods ...
Risk of unnatural death following self-harm in South Africa: development and validation of multivariable prognostic models [0.03%]
南非自杀后发生非自然死亡的风险：多变量预后模型的建立和验证
Veronika Whitesell Skrivankova,Roxanne Pelteret,Stephan Rabie et al.
Veronika Whitesell Skrivankova et al.
Background: Recurrent self-harm is common and is associated with an increased risk of unnatural death including suicide and fatal accidents. We developed and validated prognostic models to stratify individuals by risk of ...
Leveraging simulation to provide a practical framework for estimating the novel scope of risk of large language models in healthcare [0.03%]
利用模拟提供一个实用框架来估计大型语言模型在医疗保健领域的新风险范围
Mark Kalinich,James Luccarelli,John Santa Maria Jr et al.
Mark Kalinich et al.
Background: Large language models (LLMs) are rapidly entering clinical and consumer use, yet their probabilistic outputs have delivered a variety of unsafe user responses. Difficulties in quantifying and mitigating risks ...
Depressive symptoms in chronic kidney disease: the hidden role of uremic toxins [0.03%]
慢性肾脏病的抑郁症状：尿毒症毒素的隐秘作用
Hélène Levassort,Sophie Liabeuf,Julie Boucquemont et al.
Hélène Levassort et al.
Background: Depression is closely linked to neuroinflammation, and in chronic kidney disease, the accumulation of uremic toxins (UTs) may promote neuroinflammatory processes through the activation of inflammatory pathways...
Genetic investigation of non-affective psychosis and depression as causal risk factors for dementia [0.03%]
精神分裂症和抑郁症的遗传学研究作为痴呆的因果风险因素
Valentina Escott-Price,Emily Simmonds,Michael J Owen et al.
Valentina Escott-Price et al.
Background: Major psychiatric disorders are associated with increased risk of dementia but establishing whether psychiatric disorders causally increase dementia risk is challenging because dementia pathology can precede c...
Unmasking microaggressions: Experiences of women in clinical and academic psychiatry and the need for systemic reform [0.03%]
揭露微歧视：女性在临床精神病学和学术界中的经历及制度改革的需求
Margaret Isioma Ojeahere,Anna Rebeka Szczegielniak,Helena Niu et al.
Margaret Isioma Ojeahere et al.
Microaggressions constitute a pervasive and insidious form of discrimination, frequently manifesting as subtle, unconscious and unintentional actions that disproportionately affect individuals based on gender, race, ethnicity, religion, age...
Building evidence on digital psychotherapies for adults living with depression: a systematic scoping review of populations, interventions and design features of ongoing and planned randomised controlled trials [0.03%]
构建成人抑郁症患者的数字心理疗法证据：正在进行和计划中的随机对照试验的人群、干预措施及设计特征的系统评价
Etienne Karl Duranté,Christopher James Veal,Blandine Thibout et al.
Etienne Karl Duranté et al.
Background: Digital psychotherapies may offer scalable options for depression, but most randomised controlled trials (RCTs) are at moderate or high risk of bias. Mapping the methodologies, populations, interventions and o...
Julian Mutz,Lachlan Gilchrist,Andrea G Allegrini et al.
Julian Mutz et al.
Background: Individuals with mental disorders face excess morbidity and premature mortality. Accelerated ageing has been proposed as a contributing mechanism but population-scale evidence across diverse diagnoses is limit...
ADHD medication discontinuation and non-adherence: a Norwegian population-based register study [0.03%]
一项基于挪威全国登记册的研究：注意缺陷多动障碍药物的停药与不依从性研究
Miguel Garcia-Argibay,Tore Hofstad,Ingvar Bjelland et al.
Miguel Garcia-Argibay et al.
Background: Poor persistence and adherence to attention-deficit/hyperactivity disorder (ADHD) medication is a significant barrier to effective long-term care, particularly during adolescence, yet age-specific and sex-spec...
Unheard voices: the overlooked mental health toll of climate change in vulnerable communities [0.03%]
被忽视的声音：气候变化对脆弱社区心理健康的影响不容小觑
Kristina Zeljic,Nambinina Rasolomalala,Julia E Michalek et al.
Kristina Zeljic et al.
Climate change has an increasing physical and mental health toll on young people globally. In this Perspective, we suggest that the extent of mental health impacts is likely to be underestimated in the low- and middle-income countries which...