7-Dehydrocholesterol protects against circadian disruption and experimental colitis: potential role of RORα/γ [0.03%]
7-脱氢胆固醇通过保护节律紊乱预防实验性结肠炎：RORα/γ的潜在作用
Feng Li,Shubin Lin,Zhiyi Tan et al.
Feng Li et al.
Transcript profile of CLSTN3B gene in human white adipose tissue is associated with obesity and mitochondrial gene program [0.03%]
人类白色脂肪组织中CLSTN3B基因的转录谱与肥胖和线粒体基因程序相关
Ningning Bai,Xuhong Lu,Yansu Wang et al.
Ningning Bai et al.
Manganese therapy for dyslipidemia and plaque reversal in murine models [0.03%]
manganese疗法治疗小鼠模型的血脂异常和斑块逆变
Yawei Wang,Xin Feng,Wenjing Zhou et al.
Yawei Wang et al.
Precise control of circulating lipid levels is vital in both health and disease. We recently uncovered that bulk lipids, transported by lipoproteins, enter the circulation initially via the coat protein complex II (COPII) in a condensation-...
DIESL fuels a DGAT-independent triglyceride synthesis pathway [0.03%]
3-吲哚甲醇通过一种不依赖DGAT的甘油三酯合成途径发挥作用
Lauren F Uchiyama,Peter Tontonoz
Lauren F Uchiyama
Single-nucleus RNA sequencing reveals heterogeneity among multiple white adipose tissue depots [0.03%]
单核RNA测序揭示多种白色脂肪组织的异质性
Limin Xie,Wanyu Hu,Haowei Zhang et al.
Limin Xie et al.
Regardless of its anatomical site, adipose tissue shares a common energy-storage role but exhibits distinctive properties. Exploring the cellular and molecular heterogeneity of white adipose tissue (WAT) is crucial for comprehending its fun...
Regulation of hepatic lipid metabolism by intestine epithelium-derived exosomes [0.03%]
肠上皮源性外泌体对肝脏脂质代谢的调节作用
Tiange Feng,Yuan Liang,Lijun Sun et al.
Tiange Feng et al.
The "gut-liver axis" is critical for the control of hepatic lipid homeostasis, where the intestine affects the liver through multiple pathways, such as nutrient uptake, gastrointestinal hormone release, and gut microbiota homeostasis. Wheth...
Liming Wang,Han-Ming Shen
Liming Wang
Fluorescent visualization and evaluation of NPC1L1-mediated vesicular endocytosis during intestinal cholesterol absorption in mice [0.03%]
小鼠肠道胆固醇吸收中NPC1L1介导的胞吞作用的荧光可视化及评价
Xiaojing Wu,Xian-Hua Ma,Jie Lin et al.
Xiaojing Wu et al.
Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is an independent risk factor for atherosclerotic cardiovascular disease. Niemann-Pick C1-like 1 (NPC1L1) is a major membr...
Dougall Norris,Yvette Aw,Hongyuan Yang
Dougall Norris
Na Li,Tiffany Horng
Na Li