Single-nucleus RNA sequencing reveals heterogeneity among multiple white adipose tissue depots [0.03%]
单核RNA测序揭示多种白色脂肪组织的异质性
Limin Xie,Wanyu Hu,Haowei Zhang et al.
Limin Xie et al.
Regardless of its anatomical site, adipose tissue shares a common energy-storage role but exhibits distinctive properties. Exploring the cellular and molecular heterogeneity of white adipose tissue (WAT) is crucial for comprehending its fun...
Regulation of hepatic lipid metabolism by intestine epithelium-derived exosomes [0.03%]
肠上皮源性外泌体对肝脏脂质代谢的调节作用
Tiange Feng,Yuan Liang,Lijun Sun et al.
Tiange Feng et al.
The "gut-liver axis" is critical for the control of hepatic lipid homeostasis, where the intestine affects the liver through multiple pathways, such as nutrient uptake, gastrointestinal hormone release, and gut microbiota homeostasis. Wheth...
Liming Wang,Han-Ming Shen
Liming Wang
Fluorescent visualization and evaluation of NPC1L1-mediated vesicular endocytosis during intestinal cholesterol absorption in mice [0.03%]
小鼠肠道胆固醇吸收中NPC1L1介导的胞吞作用的荧光可视化及评价
Xiaojing Wu,Xian-Hua Ma,Jie Lin et al.
Xiaojing Wu et al.
Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is an independent risk factor for atherosclerotic cardiovascular disease. Niemann-Pick C1-like 1 (NPC1L1) is a major membr...
Dougall Norris,Yvette Aw,Hongyuan Yang
Dougall Norris
Na Li,Tiffany Horng
Na Li
Ablation of Mea6/cTAGE5 in oligodendrocytes significantly impairs white matter structure and lipid content [0.03%]
MEA6/cTAGE5缺失影响少突胶质细胞的脂质含量和髓鞘形成
Tiantian Ma,Wei Mao,Shaohua Zhang et al.
Tiantian Ma et al.
Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons. Abnormal myelin sheath is associated with many neurological diseases. Meningioma-expressed antigen 6 (Mea6)/cutaneous T cell lymphoma-associated an...
Camille Allard,Daniela Cota
Camille Allard
A new journal for a new age [0.03%]
一个新时代的新期刊
Peng Li,John R Speakman
Peng Li
Xu Wang,Shen-Ying Liu,Guo-Sheng Hu et al.
Xu Wang et al.
Brown adipose tissue (BAT) plays a key role in thermogenesis during acute cold exposure. However, it remains unclear how BAT is prepared to rapidly turn on thermogenic genes. Here, we show that damage-specific DNA binding protein 1 (DDB1) m...