Chronic cold exposure reprograms feeding-regulated LPL activity in white adipose tissues through hepatic ANGPTL3 and ANGPTL8 [0.03%]
慢性寒冷暴露通过肝脏ANGPTL3和ANGPTL8重新编程白色脂肪组织中的喂养调节的LPL活性
Yiliang Zhang,Shengyang Zhou,Runming Zhao et al.
Yiliang Zhang et al.
Graphical Abstract Lipoprotein lipase (LPL) mediates peripheral tissue triglyceride (TG) uptake. Hepatic ANGPTL3 (A3) and ANGPTL8 (A8) form a complex and inhibit LPL activity in the white adipose tissue (WAT) via systematic circulation. ANG...
The deuterated glucose insulin tolerance test: a new tool to delineate insulin-stimulated glucose uptake from suppression of endogenous glucose production [0.03%]
氘代葡萄糖耐量试验：一个界定胰岛素刺激的葡萄糖摄取和抑制内源性葡萄糖产生的新工具
Christian A Unger,Marion C Hope rd,Michael Chase Kettering et al.
Christian A Unger et al.
Graphical Abstract. © The Author(s) 2024. Published by Oxford University Press on behalf of Higher Education Press.
Hai Wang,Zhiming Shao
Hai Wang
CIDEC/FSP27 exacerbates obesity-related abdominal aortic aneurysm by promoting perivascular adipose tissue inflammation [0.03%]
CIDEC/FSP27通过促进血管周围脂肪组织炎症加重肥胖相关性腹主动脉瘤
Qing Zhu,Da Luo,Yining Li et al.
Qing Zhu et al.
Abdominal aortic aneurysm (AAA) is strongly correlated with obesity, partially due to the abnormal expansion of abdominal perivascular adipose tissue (PVAT). Cell death-inducing DNA fragmentation factor-like effector C (CIDEC), also known a...
Glucose-6-phosphate dehydrogenase regulates mitophagy by maintaining PINK1 stability [0.03%]
葡萄糖六磷酸脱氢酶通过维持PINK1稳定性调节线粒体自噬
Yik-Lam Cho,Hayden Weng Siong Tan,Jicheng Yang et al.
Yik-Lam Cho et al.
Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme in the pentose phosphate pathway (PPP) in glycolysis. Glucose metabolism is closely implicated in the regulation of mitophagy, a selective form of autophagy for the degrad...
Gut microbiota, immunity, and bile acid metabolism: decoding metabolic disease interactions [0.03%]
肠道微生物群、免疫和胆汁酸代谢：解码代谢性疾病间的相互作用
Qixiang Zhao,Jiayu Wu,Yong Ding et al.
Qixiang Zhao et al.
In recent decades, the global prevalence of metabolic syndrome has surged, posing a significant public health challenge. Metabolic disorders, encompassing diabetes, obesity, nonalcoholic fatty liver disease, and polycystic ovarian syndrome,...
7-Dehydrocholesterol protects against circadian disruption and experimental colitis: potential role of RORα/γ [0.03%]
7-脱氢胆固醇通过保护节律紊乱预防实验性结肠炎：RORα/γ的潜在作用
Feng Li,Shubin Lin,Zhiyi Tan et al.
Feng Li et al.
Transcript profile of CLSTN3B gene in human white adipose tissue is associated with obesity and mitochondrial gene program [0.03%]
人类白色脂肪组织中CLSTN3B基因的转录谱与肥胖和线粒体基因程序相关
Ningning Bai,Xuhong Lu,Yansu Wang et al.
Ningning Bai et al.
Manganese therapy for dyslipidemia and plaque reversal in murine models [0.03%]
manganese疗法治疗小鼠模型的血脂异常和斑块逆变
Yawei Wang,Xin Feng,Wenjing Zhou et al.
Yawei Wang et al.
Precise control of circulating lipid levels is vital in both health and disease. We recently uncovered that bulk lipids, transported by lipoproteins, enter the circulation initially via the coat protein complex II (COPII) in a condensation-...
DIESL fuels a DGAT-independent triglyceride synthesis pathway [0.03%]
3-吲哚甲醇通过一种不依赖DGAT的甘油三酯合成途径发挥作用
Lauren F Uchiyama,Peter Tontonoz
Lauren F Uchiyama