Circulating short-chain and branched short-chain fatty acids and the risk of incident type 2 diabetes: findings from the 4C study [0.03%]
循环短链和支链脂肪酸与2型糖尿病发病风险的关系：4C研究的结果
Shuangyuan Wang,Hong Lin,Xiaojing Jia et al.
Shuangyuan Wang et al.
Previous studies suggested that fecal short-chain fatty acids (SCFAs) and branched short-chain fatty acids (BCFAs) are associated with glucose regulation. However, the potential relationship between circulating SCFAs and BCFAs with incident...
[This corrects the article DOI: 10.1093/lifemeta/loae034.]. © The Author(s) 2025. Published by Oxford University Press on behalf of Higher Education Pre...
Published Erratum
Life metabolism. 2025 Mar 10;4(2):loaf007. DOI:10.1093/lifemeta/loaf007 2025
Correction to: Hierarchical inhibition of mTORC1 by glucose starvation-triggered AXIN lysosomal translocation and by AMPK [0.03%]
Correction to：由AXIN溶酶体易位介导的葡萄糖饥饿触发的以及AMPK介导的mTORC1抑制的层次结构
[This corrects the article DOI: 10.1093/lifemeta/load005.]. © The Author(s) 2025. Published by Oxford University Press on behalf of Higher Education Pre...
Published Erratum
Life metabolism. 2025 Feb 12;4(2):loaf003. DOI:10.1093/lifemeta/loaf003 2025
Serotonin signaling to regulate energy metabolism: a gut microbiota perspective [0.03%]
从肠道微生物组角度探讨五羟色胺信号对能量代谢的调节作用
Guoli Li,Sijing Dong,Chunhao Liu et al.
Guoli Li et al.
Serotonin is one of the most potent gastrointestinal, peripheral, and neuronal signaling molecules and plays a key role in regulating energy metabolism. Accumulating evidence has shown the complex interplay between gut microbiota and host e...
The FTO variant conferring enhanced UCP1 expression is linked to human migration out of Africa [0.03%]
与人类非洲迁徙相关的FTO基因变异可增强UCP1表达
Nan Yin,Dan Zhang,Jiqiu Wang
Nan Yin
Phytic acid-based nanomedicine against mTOR represses lipogenesis and immune response for metabolic dysfunction-associated steatohepatitis therapy [0.03%]
基于植酸的纳米药物通过抑制mTOR对抗脂质生成和免疫反应以治疗与代谢功能障碍相关的steatohepatitis
Fenghua Xu,Shoujie Zhao,Yejing Zhu et al.
Fenghua Xu et al.
Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common chronic liver diseases and is mainly caused by metabolic disorders and systemic inflammatory responses. Recent studies have indicated that the activation of t...
Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD [0.03%]
空间多组学揭示GPR35相关脂质代谢标志物在MASLD肝脏区域化中的特征
Wuxiyar Otkur,Yiran Zhang,Yirong Li et al.
Wuxiyar Otkur et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a metabolic disease that can progress to metabolic dysfunction-associated steatohepatitis (MASH), cirrhosis, and cancer. The zonal distribution of biomolecules in the liver...
Jianping Ye,Jun Yin
Jianping Ye
Type 2 diabetes mellitus (T2DM) is closely associated with obesity, while interactions between the two diseases remain to be fully elucidated. To this point, we offer this perspective to introduce a set of new insights into the interpretati...
Gut bacterial metabolism produces neuroactive steroids in pregnant women [0.03%]
妊娠妇女肠道细菌代谢产生神经活性类固醇
Kelsey E Huus,Ruth E Ley
Kelsey E Huus
Biphasic glucose-stimulated insulin secretion over decades: a journey from measurements and modeling to mechanistic insights [0.03%]
几十年来的双相葡萄糖刺激的胰岛素分泌：从测量和建模到机制见解的一次旅程
Xiaohong Peng,Kai Wang,Liangyi Chen
Xiaohong Peng
Glucose-stimulated insulin release from pancreatic β-cells is critical for maintaining blood glucose homeostasis. An abrupt increase in blood glucose concentration evokes a rapid and transient rise in insulin secretion followed by a prolon...