Life Metabolism Editorial Team
Life Metabolism Editorial Team
Liver ERα mediates sex differences in metabolic pattern changes in response to time-restricted feeding [0.03%]
肝脏ERα介导了限时喂养应激下代谢模式改变的性别差异响应
Haoqi Zhang,Tengteng Huang,Xianyang Jin et al.
Haoqi Zhang et al.
Time-restricted feeding (TRF) is a dietary strategy used to prevent and treat obesity in both sexes. However, TRF affects liver metabolism differently in males and females, and the mechanisms behind these differences remain unclear. Our stu...
Combination of time-restricted feeding with resistance exercise ameliorates MAFLD and improves glycemic homeostasis in obese mice [0.03%]
时间限制性进食与抵抗锻炼联合改善肥胖小鼠非酒精性脂肪肝及糖代谢紊乱
Guilherme Domingos Brisque,Ana Paula Azevêdo Macêdo,Guilherme Soderini Erlich et al.
Guilherme Domingos Brisque et al.
DHHC5 regulates lacteal function and intestinal lipid absorption by maintaining VEGFR2 localization in lipid rafts [0.03%]
DHHC5通过维持脂筏中VEGFR2定位来调节乳糜管功能和肠道脂质吸收
Yin-Yue Zhao,Yi-Fan Li,Jian-Wei Hao et al.
Yin-Yue Zhao et al.
The intestinal lymphatic system is essential for lipid absorption, yet its regulatory mechanisms remain poorly understood. Here, we identify DHHC5, an Asp-His-His-Cys (DHHC) motif-containing palmitoyl acyltransferase, as a critical regulato...
Baf60c in skeletal muscle regulates adipose tissue thermogenesis via Musclin-mediated endocrine signaling [0.03%]
骨骼肌中的Baf60c通过Musclin介导的内分泌信号调节脂肪组织产热作用
Shuang Han,Lu Jin,Wei Peng et al.
Shuang Han et al.
Skeletal muscle plays a key role in metabolic homeostasis. Brg1/Brm-associated factor (Baf) 60c, a subunit of the mating type switching/sucrose non-fermenting (SWI/SNF) chromatin remodeling complexes, was previously identified to be robustl...
Yingxi Xu,Chen Wang,Ping-Chih Ho
Yingxi Xu
Circadian rhythms are fundamental regulators of physiological processes, including immune function. Recent insights uncover that not only lymphocytes but also myeloid cells possess intrinsic circadian clocks that govern their behavior and f...
Dietary sulfur amino acid restriction improves metabolic health by reducing fat mass [0.03%]
饮食中的硫氨基酸限制通过减少脂肪量来改善代谢健康
Chenhao Xin,Mingcheng Cai,Qianxi Jia et al.
Chenhao Xin et al.
Diet interventions such as calorie restriction or time-restricted feeding offer potential for weight management, but long-term success is often hindered by poor adherence due to the rewarding effects of sugars. In this study, we demonstrate...
Brain-body mitochondrial distribution patterns lack coherence and point to tissue-specific regulatory mechanisms [0.03%]
脑-体组织的线粒体分布模式缺乏一致性并暗示了特定组织的调节机制
Jack Devine,Anna S Monzel,David Shire et al.
Jack Devine et al.
Energy transformation capacity is generally assumed to be a coherent individual trait driven by genetic and environmental factors. This predicts that some individuals should have consistently high, while others show consistently low mitocho...
Transporters in vitamin uptake and cellular metabolism: impacts on health and disease [0.03%]
维生素吸收和细胞代谢中的转运蛋白：对健康与疾病的影响
Yaxuan Yuan,Ligong Chen
Yaxuan Yuan
Vitamins are vital nutrients essential for metabolism, functioning as coenzymes, antioxidants, and regulators of gene expression. Their absorption and metabolism rely on specialized transport proteins that ensure bioavailability and cellula...
Optimized upstream analytical workflow for single-nucleus transcriptomics in main metabolic tissues [0.03%]
主要代谢组织单核转录组学的优化上游分析工作流程
Pengwei Dong,Shitong Ding,Guanlin Wang
Pengwei Dong