Antipsychotic discontinuation in schizophrenia: rational or reckless? [0.03%]
精神分裂症患者的抗精神病药减停究竟合理还是鲁莽？
Robert B Zipursky,Ofer Agid,Gary Remington
Robert B Zipursky
Association between metabolic syndrome, diabetes mellitus, inflammation and cognitive dysfunctions in schizophrenia: a cross-sectional analysis [0.03%]
精神分裂症患者代谢综合征、糖尿病、炎症与认知功能障碍的相关性研究：横断面分析
Alexander Kancsev,Marie Anne Engh,András Attila Horváth et al.
Alexander Kancsev et al.
Metabolic syndrome (MetS) and diabetes mellitus (DM) are frequent in schizophrenia (SCZ) and have been linked to cognitive impairment and low-grade inflammation. In this cross-sectional study of adults with DSM-5 SCZ (N = 218; SCZ = 103, SC...
Analysis of conceptual overlap among formal thought disorder rating scales in psychosis: a systematic semantic synthesis [0.03%]
系统语义综合在精神病理中正式思维障碍评估量表的概念重叠分析
Alban Voppel,Silvia Ciampelli,Tilo Kircher et al.
Alban Voppel et al.
Measuring Formal Thought Disorder (FTD), a common, cross-diagnosed symptom dimension across mental disorders, is plagued by numerous inconsistencies. Clinicians use either FTD-specific scales or items from generic scales. While these tools ...
AVATAR therapy for medication-resistant auditory hallucination in patients with psychosis: a systematic review and meta-analysis [0.03%]
难治性精神病患者听觉幻听的治疗：系统评价和荟萃分析
Tien-Wei Hsu,Ping-Tao Tseng,Chih-Wei Hsu et al.
Tien-Wei Hsu et al.
Auditory hallucination (AH) is a distressing and disabling symptom in patients with schizophrenia spectrum disorder, particularly in those who do not respond to antipsychotics. The aim of this study is to examine the efficacy of AVATAR (Aud...
Alterations in serum IL-10 and IL-19 levels in drug-naïve first-episode adolescent-onset schizophrenia and their associations with clinical symptoms [0.03%]
首次发作青少年精神分裂症患者外周血IL-10和IL-19水平的变化及临床意义
Haidong Yang,Zhihui Shi,Li Xu et al.
Haidong Yang et al.
Immune-inflammatory mechanisms in schizophrenia have received widespread attention, but the levels of interleukin-10 (IL-10) and interleukin-19 (IL-19) and their associations with clinical symptoms in adolescent-onset schizophrenia (AOS) re...
Trajectory analysis of BMI increase induced by second-generation antipsychotics in first-episode schizophrenia: a secondary analysis based on CNFEST*** [0.03%]
二代抗精神病药所致BMI增长轨迹在首发精神分裂症患者中的影响因素分析——CNFEST的探索性二次分析
Xiaolin Yin,Tianhang Zhou,Bingjie Huang et al.
Xiaolin Yin et al.
Antipsychotic-induced weight gain (AIWG) exhibits marked heterogeneity. We conducted a secondary analysis of the Chinese First-Episode Schizophrenia Trial, leveraging frequent body mass index (BMI) measurements over 12 months. Our aims were...
Syntactic network analysis in first-episode psychosis: toward generalizability [0.03%]
首次精神病发作的句法网络分析：迈向通用性
Silvia Ciampelli,Janna Niña de Boer,Alban Elias Voppel et al.
Silvia Ciampelli et al.
Automated syntactic markers distinguished patients with first-episode psychosis from healthy controls in a Brazilian Portuguese-speaking sample, achieving 81% cross-validated accuracy (AUC = 0.86). These findings largely replicate prior res...
Feasibility and acceptability study of an engagement intervention for family members in early intervention programs for psychosis [0.03%]
早期精神病干预项目中面向家庭成员的参与式干预措施实证和认可度研究
Oladunni Oluwoye,Bryony Stokes,Karina Silva Garcia et al.
Oladunni Oluwoye et al.
Despite evidence supporting the involvement of family members in early-intervention services for psychosis, rates of family engagement have been relatively low, and disparities exist. This study investigated the acceptability, feasibility, ...
Differentially expressed mRNAs of neural signaling pathway genes in peripheral blood leukocytes as biomarkers for schizophrenia [0.03%]
外周血白细胞神经信号通路基因差异表达的mRNA作为精神分裂症生物标志物的研究
Yuan Zhou,Mengya Zhu,Yao Fan et al.
Yuan Zhou et al.
Abnormal neurotransmitter regulation plays a role in the pathogenesis of Schizophrenia (SCZ), and the presence of brain tissue-like aberrant expression in the partial transcriptome of peripheral blood leukocytes from patients with SCZ sugge...
Prevalence and associated factors of metabolic syndrome in patients with schizophrenia: a multicenter cross-sectional study in China [0.03%]
中国多中心横断面研究的精神分裂症患者的代谢综合征患病率及影响因素研究
Zhengluan Liao,Junjie Lin,Yaguan Zhou et al.
Zhengluan Liao et al.
Metabolic syndrome (MetS) is highly prevalent among individuals with schizophrenia. However, substantial regional variation exists, and evidence from large samples of hospitalized patients in China remains limited. This study aimed to estim...