Spontaneous head movements during virtual clinical interviews help predict 12-months clinical outcomes in youth at clinical high risk for psychosis [0.03%]
临床高危青少年人群在虚拟临床访谈过程中自发性头部运动可预测其12月后的临床转归
Juliette Lozano-Goupil,Sophia Parmacek,James M Gold et al.
Juliette Lozano-Goupil et al.
Identifying predictors of clinical and functioning outcomes in individuals at clinical high risk (CHR) for psychosis is essential to early intervention and symptom monitoring. While motor abnormalities have been established as core features...
Altered white matter microstructure of language pathways and semantic cognition deficiencies in early psychosis [0.03%]
早期精神病患者的语言途径异常和语义认知缺陷
Werner Surbeck,Wolfgang Omlor,Noemi Dannecker et al.
Werner Surbeck et al.
Semantic language dysfunction is a hallmark of early psychosis, yet the underlying brain structural correlates are largely unexplored. In particular, it is unclear whether core deficits arise from disruptions to semantic representation, whi...
Dementia in older adults with schizophrenia: a 12-year analysis of prevalence, incidence, and treatment patterns in South Korea [0.03%]
韩国老年精神病患者痴呆症的患病率、发病率和治疗模式：一项为期12年的分析研究
Jung Su Park,Sangwan Kim,Donghoon Jeong et al.
Jung Su Park et al.
Older adults with schizophrenia face a significantly elevated risk of dementia. However, recent trends remain unclear within South Korea's rapidly aging schizophrenia population. This study aimed to quantify the burden of dementia in older ...
Depressive symptomatology in the first-episode schizophrenia spectrum disorders OPTiMiSE trial: prevalence, correlates, symptom progression and outcomes [0.03%]
首次发作的精神分裂症谱系障碍中的抑郁症状学：OPTiMiSE试验中的流行病学、相关因素、症状进展和预后
Javier-David Lopez-Morinigo,David Fraguas,Covadonga M Diaz-Caneja et al.
Javier-David Lopez-Morinigo et al.
Numerous aspects of depressive symptomatology in first-episode schizophrenia spectrum disorders (FES) remain unclear. Based on data from the FES OPTiMiSE trial, we estimated the prevalence of depression (Calgary Depression Scale for Schizop...
Peripheral NMDAR subunits as predictors of working memory improvement in schizophrenia [0.03%]
精神分裂症患者工作记忆改善的预测指标：周边NMDAR亚单位的作用
Xiangqin Qin,Wenpeng Hou,Zhen Mao et al.
Xiangqin Qin et al.
Cognitive dysfunction is a defining characteristic impairing social functioning in schizophrenia (SZ). N-methyl-D-aspartate receptor (NMDAR) hypofunction may underlie these impairments. This study explored the association between peripheral...
Temporal integration window of sensory processing as a neuropsychological marker for clinical high risk of psychosis [0.03%]
临床前精神病高危人群感觉信息加工的时间窗整合作为神经心理学标志物
Shuo Lin,Lu Tian,Wei-Hao Tan et al.
Shuo Lin et al.
Early identification of individuals with clinical high risk (CHR) for psychosis relies heavily on subjective assessments, necessitating the exploration of objective markers to enhance diagnostic accuracy. This study aimed to evaluate the te...
Prevalence and incidence of treated schizophrenia: temporal and regional trends in Germany [0.03%]
德国精神分裂症患病率和发病率的时空变化规律研究
Oliver Riedel,Christian J Bachmann,Robert A Bittner et al.
Oliver Riedel et al.
Schizophrenia ranks among the top ten causes of disability worldwide. The provision of healthcare services requires estimates on the epidemiology of schizophrenia, but recent data for Germany are lacking. Based on a large German health clai...
Turn-taking fluency in free conversations with individuals diagnosed with schizophrenia [0.03%]
精神分裂症患者的自由对话中的轮流发言流畅度研究
Tifenn Fauviaux,Ghilès Mostafaoui,Richard C Schmidt et al.
Tifenn Fauviaux et al.
Disruptions in language processing observed in Individuals diagnosed with schizophrenia (ISZ) are likely to impair turn-taking fluency and social functioning. While turn-taking research in ISZ is limited and mostly interview-based, this stu...
Low awareness of clozapine-induced agranulocytosis in a mixed-method survey of 354 patients and carers [0.03%]
一项针对354名患者和护理人员的混合方法调查发现克洛扎平导致中性粒细胞减少症的意识较低
Ebenezer Oloyede,Von-de-Viel Nettey,Olubanke Dzahini et al.
Ebenezer Oloyede et al.
Current preventative measures for clozapine-induced agranulocytosis (CIA) include indefinite haematological monitoring. Another safeguard against CIA is patient and carer education to identify and respond to potential symptoms of this adver...
Decreased levels of platelet-derived growth factor subtypes and superoxide dismutase isoenzymes in early-onset schizophrenia [0.03%]
早期发病的 schizophrenia 中血小板衍生生长因子亚型及超氧化物歧化酶同工酶水平降低
Haidong Yang,Zhihui Shi,Lingshu Luan et al.
Haidong Yang et al.
Early-onset schizophrenia (EOS) patients are at greater risk of poor long-term outcomes compared to later-onset patients, so it is essential to identify unique pathomechanisms and prognostic biomarkers for this EOS patient group. Deficits i...