Clustering of cognitive subtypes in schizophrenia patients and their siblings: relationship with regional brain volumes [0.03%]
精神分裂症患者及其同胞的认知亚型聚类及与脑区体积的关系
Erkan Alkan,Simon L Evans
Erkan Alkan
Schizophrenia patients (SZH) often show impaired cognition and reduced brain structural volumes; these deficits are also detectable in healthy relatives of SZH. However, there is considerable heterogeneity: a sizable percentage of SZH are r...
White matter microstructure of superior longitudinal fasciculus II is associated with intelligence and treatment response of negative symptoms in patients with schizophrenia [0.03%]
上纵束II型白质微结构与精神分裂症患者的智力和阴性症状治疗反应相关
Joonho Lee,Jong-Soo Oh,Chun-Il Park et al.
Joonho Lee et al.
Although the potential role of superior longitudinal fasciculus (SLF) in intellectual deficits and treatment response (TR) in patients with schizophrenia (SZ) has been previously described, little is known about the white-matter (WM) integr...
The efficacy of transcranial magnetic stimulation (TMS) for negative symptoms in schizophrenia: a systematic review and meta-analysis [0.03%]
经颅磁刺激治疗精神分裂症阴性症状的有效性：系统评价和meta分析
Rasmus Lorentzen,Tuan D Nguyen,Alexander McGirr et al.
Rasmus Lorentzen et al.
Several trials have shown preliminary evidence for the efficacy of transcranial magnetic stimulation (TMS) as a treatment for negative symptoms in schizophrenia. Here, we synthesize this literature in a systematic review and quantitative me...
Impaired verbal memory function is related to anterior cingulate glutamate levels in schizophrenia: findings from the STRATA study [0.03%]
精神分裂症患者受损的言语记忆功能与前扣带回谷氨酸水平有关：STRATA研究结果
Kira Griffiths,Alice Egerton,Edward Millgate et al.
Kira Griffiths et al.
Impaired cognition is associated with lower quality of life and poor outcomes in schizophrenia. Brain glutamate may contribute to both clinical outcomes and cognition, but these relationships are not well-understood. We studied a multicentr...
Gene co-expression architecture in peripheral blood in a cohort of remitted first-episode schizophrenia patients [0.03%]
首发精神分裂症缓解期患者外周血基因共表达网络分析
Natalia Rodríguez,Patricia Gassó,Albert Martínez-Pinteño et al.
Natalia Rodríguez et al.
A better understanding of schizophrenia subtypes is necessary to stratify the patients according to clinical attributes. To explore the genomic architecture of schizophrenia symptomatology, we analyzed blood co-expression modules and their ...
Occurrence and phenomenology of hallucinations in the general population: A large online survey [0.03%]
基于大规模在线调查的一般人群中的幻觉的流行病学和临床特点研究
Mascha M J Linszen,Janna N de Boer,Maya J L Schutte et al.
Mascha M J Linszen et al.
Although epidemiological studies report that hallucinations occur in 6-15% of the general population, little is known about their phenomenology. To overcome this paucity, this study investigates the phenomenological characteristics of hallu...
The neural substrates of neurological soft signs in schizophrenia: a systematic review [0.03%]
精神分裂症神经软体征的神经基础：系统综述
Genelle D Samson,Adrienne C Lahti,Nina V Kraguljac
Genelle D Samson
Neurological soft signs (NSS) are common in patients with schizophrenia. However, the neural substrates of NSS remain poorly understood. Using legacy PubMed, we performed a systematic review and included studies that assessed NSS and obtain...
Robin Emsley
Robin Emsley
Estimation of the bidirectional relationship between schizophrenia and inflammatory bowel disease using the mendelian randomization approach [0.03%]
利用孟德尔随机化方法估计精神分裂症和炎症性肠病之间的双向关系
Li Qian,Xiaoyan He,Fengjie Gao et al.
Li Qian et al.
It has been reported that schizophrenia (SCZ) and inflammatory bowel disease (IBD) are related. However, whether there is a bidirectional interaction between them remains unclear. The aim of this study was to conduct a bidirectional Mendeli...
Adult stress exposure blunts dopamine system hyperresponsivity in a neurodevelopmental rodent model of schizophrenia [0.03%]
成年期压力暴露减弱了神经发育性啮齿动物精神分裂症模型中的多巴胺系统过度反应现象
Millie Rincón-Cortés,Anthony A Grace
Millie Rincón-Cortés
Stress is a major risk factor for the development of both schizophrenia and depression, and comorbidity between the two is common in schizoaffective disorders. However, the effects of stress exposure (i.e. chronic mild stress-CMS) on depres...