Diminished anticipatory-consummatory pleasure interplay in high schizotypal traits and subthreshold depression: potential risk for schizophrenia and depression [0.03%]
高分裂型特质和次阈值抑郁中预期-消费乐趣互动减弱:精神分裂症和抑郁症的风险指标
Lei Shen,Chi Xie,Chang Liu et al.
Lei Shen et al.
Anhedonia is a multidimensional construct encompassing anticipatory and consummatory pleasure, and it manifests across a range of psychiatric disorders including schizophrenia (SCZ) and major depressive disorder (MDD). However, the shared a...
Machine learning-based predictive models and subtypes patterns in peripheral blood of schizophrenia based on a machine learning computational framework [0.03%]
基于机器学习的计算框架的精神分裂症外周血液预测模型和亚型模式研究
Zhijun Li,Qing Sun,Haoyu Li et al.
Zhijun Li et al.
Schizophrenia (SCZ) is a complex psychiatric disorder, and its pathogenic mechanisms are not yet fully understood. The identification of reliable blood biomarkers and molecular subtypes for early diagnosis and effective therapy remains a si...
Rethinking language, cognition and assessment in psychosis: How bilingualism challenges psychiatry and how natural language processing can help [0.03%]
精神病障碍的语言、认知与评估的再思考:双语对精神医学带来的挑战和自然语言处理可能提供的帮助
Sandra Anna Just,Vincent DeLuca,Jason Rothman et al.
Sandra Anna Just et al.
Language plays a central role in the assessment of individuals with psychosis, from taking a medical history to evaluating cognitive function. However, speaking multiple languages can significantly influence linguistic, cognitive and neural...
Sleep and wake markers of thalamocortical functioning in early-course psychosis and first-degree relatives [0.03%]
早发性精神病和一级亲属的觉醒与睡眠标记及丘脑皮层功能
Bengi Baran,Dan Denis,Dimitrios Mylonas et al.
Bengi Baran et al.
Thalamocortical circuits regulate information flow between sensory inputs and higher-order processing, and their disruption is increasingly implicated in psychotic disorders. However, scalable biomarkers of this circuitry remain limited. We...
In vivo mapping of protein-protein interactions of schizophrenia risk factors generates an interconnected disease network [0.03%]
精神分裂症风险因素的蛋白质间相互作用的体内图谱生成了互连的疾病网络
Daniel B McClatchy,Jeff Lane,Susan B Powell et al.
Daniel B McClatchy et al.
Genetic analyses of schizophrenia (SCZ) patients have identified thousands of risk factors. In silico protein-protein interaction (PPI) network analysis has provided strong evidence that disrupted PPI networks underlie SCZ pathogenesis. In ...
An ENIGMA Consortium study of the relationship between white matter microstructure and positive and negative symptom severity in patients with schizophrenia [0.03%]
ENIGMA联盟关于精神分裂症患者白质微结构与阳性症状和阴性症状严重程度关系的研究
Aoife Warren,Laurena Holleran,Ingrid Agartz et al.
Aoife Warren et al.
Symptom severity in schizophrenia has been repeatedly associated with thinner cortical gray matter. While global and regional white matter microstructure alterations in schizophrenia are well-documented, their association with clinical symp...
Persistent negative symptoms in the EULAST cohort: impact on functional outcome [0.03%]
EULAST队列的持续性阴性症状对其功能预后的影响
Luigi Giuliani,Pasquale Pezzella,Giulia M Giordano et al.
Luigi Giuliani et al.
Persistent negative symptoms (PNS), defined as negative symptoms of at least moderate severity that endure over time and are not attributable to other psychopathological dimensions such as depression or parkinsonism, have been associated wi...
Author Correction: Semantic memory disorganization linked to social functioning in patients with schizophrenia [0.03%]
作者更正:语义记忆失序与精神分裂症患者的社交功能有关
Ayumu Wada,Chika Sumiyoshi,Naoki Yoshimura et al.
Ayumu Wada et al.
Published Erratum
Schizophrenia (Heidelberg, Germany). 2026 Feb 27;12(1):26. DOI:10.1038/s41537-026-00740-3 2026
Prevalence of anti-NMDA receptor antibodies among adult patients presenting with first-episode psychosis in Hong Kong [0.03%]
香港首次出现精神病症状的成年人中抗NMDAR抗体的阳性率
Steven Wai Ho Chau,Charis Kw Lam,Matthew Pm Yu et al.
Steven Wai Ho Chau et al.
Studies on the presence of anti-NMDA receptor antibodies were done primarily on the European population. This study investigates the prevalence of anti-NMDA antibodies among adult patients presenting with first-onset psychosis in an acute m...
Differential DNA-methylation of synaptic genes in CSF and blood in schizophrenia [0.03%]
精神分裂症中CSF和血液中突触基因的DNA甲基化差异分析
Kirsten Jahn,Adrian Groh,Ole Riemer et al.
Kirsten Jahn et al.
The dual-hit model of schizophrenic psychoses suggests that epigenetic alterations may contribute to the disease pathogenesis. Given the significant synaptic loss in patients with schizophrenia (SZ) during puberty, we investigated DNA-methy...