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期刊名:Npj schizophrenia

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e-ISSN:2754-6993

IF/分区:4.1/Q1

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Bengi Baran,Dan Denis,Dimitrios Mylonas et al. Bengi Baran et al.
Thalamocortical circuits regulate information flow between sensory inputs and higher-order processing, and their disruption is increasingly implicated in psychotic disorders. However, scalable biomarkers of this circuitry remain limited. We...
Daniel B McClatchy,Jeff Lane,Susan B Powell et al. Daniel B McClatchy et al.
Genetic analyses of schizophrenia (SCZ) patients have identified thousands of risk factors. In silico protein-protein interaction (PPI) network analysis has provided strong evidence that disrupted PPI networks underlie SCZ pathogenesis. In ...
Aoife Warren,Laurena Holleran,Ingrid Agartz et al. Aoife Warren et al.
Symptom severity in schizophrenia has been repeatedly associated with thinner cortical gray matter. While global and regional white matter microstructure alterations in schizophrenia are well-documented, their association with clinical symp...
Luigi Giuliani,Pasquale Pezzella,Giulia M Giordano et al. Luigi Giuliani et al.
Persistent negative symptoms (PNS), defined as negative symptoms of at least moderate severity that endure over time and are not attributable to other psychopathological dimensions such as depression or parkinsonism, have been associated wi...
Steven Wai Ho Chau,Charis Kw Lam,Matthew Pm Yu et al. Steven Wai Ho Chau et al.
Studies on the presence of anti-NMDA receptor antibodies were done primarily on the European population. This study investigates the prevalence of anti-NMDA antibodies among adult patients presenting with first-onset psychosis in an acute m...
Kirsten Jahn,Adrian Groh,Ole Riemer et al. Kirsten Jahn et al.
The dual-hit model of schizophrenic psychoses suggests that epigenetic alterations may contribute to the disease pathogenesis. Given the significant synaptic loss in patients with schizophrenia (SZ) during puberty, we investigated DNA-methy...
Stephanie Mehl,Christopher Hautmann,Björn Schlier et al. Stephanie Mehl et al.
Psychological interventions for delusions may be enhanced by targeting their presumed causal factors. An emotion-oriented variant of cognitive behavioral therapy for delusions (CBTd-E), designed to target affect regulation and maladaptive s...
Daniel Mamah,ShingShiun Chen,Michael P Harms et al. Daniel Mamah et al.
Resting-state fMRI studies consistently demonstrate widespread dysconnectivity in schizophrenia (SZ), yet conventional analytic methods often fail to account for individual variability in functional brain organization. This study utilized i...
Fiona Meister,Martin Sellier Silva,Gleb Melshin et al. Fiona Meister et al.
Pragmatic language impairments-difficulties using language effectively in social contexts-are common in adults suffering from severe mental illnesses (SMIs) such as schizophrenia spectrum disorders (SSD), major depressive disorder (MDD), an...