Distinct microRNA profiles in neuron-derived extracellular vesicles between recent-onset and chronic-phase schizophrenia [0.03%]
首发和慢性精神分裂症外泌体中微小核糖核酸表达谱的差异性研究
Yasufumi Tomita,Kazuya Toriumi,Mitsuhiro Miyashita et al.
Yasufumi Tomita et al.
MicroRNAs (miRNAs) are critical regulators of neurodevelopment and are implicated in the pathogenesis of schizophrenia. Schizophrenia is increasingly recognized as a neurodevelopmental disorder, with most cases emerging during late adolesce...
Insulin resistance in patients with schizophrenia: is it related to gut permeability? [0.03%]
精神分裂症患者的胰岛素抵抗与肠道通透性有关吗？
Manuel Couce-Sánchez,Francesco Dal Santo,Leticia González-Blanco et al.
Manuel Couce-Sánchez et al.
We aimed to examine the association between gut permeability biomarkers (LBP, sCD14) and insulin resistance (IR) in schizophrenia. In this cross-sectional study of 91 patients, IR (HOMA-IR ≥ 3.0) was associated with higher LBP, C-reactive ...
Mobile cognitive remote assessment of schizophrenia: a global multi-site pilot study [0.03%]
手机认知远程评估精神分裂症：一项全球多中心试点研究
Juan Castillo,Jiaee Cheong,Soumya Choudhary et al.
Juan Castillo et al.
Cognition in schizophrenia is difficult to assess in clinical settings due to the time required to administer traditional pen-and-paper tests, among other factors. Digital remote assessments completed on a smartphone offer an alternative th...
Ben Alderson Day,Peter Moseley,Angela Woods et al.
Ben Alderson Day et al.
Felt presence (FP) - sensing another person without clear sensory evidence - has been described in psychosis for over a century but rarely studied due to challenges in recognition and assessment. Recently FP has been identified as a transdi...
Spatiotemporal dynamics of RERE in schizophrenia pathogenesis: insights from multi-omics and single-cell sequencing [0.03%]
精神分裂症发病机制中RERE的时空动态变化：多组学和单细胞测序的新见解
Jing Shen,Chenxu Xiao
Jing Shen
Identification of cell type-specific and temporally dynamic regulatory features of schizophrenia (SCZ) risk genes is essential for advancing mechanistic neurobiological studies. This study systematically dissected the genetic architecture a...
Mapping aggressive behaviors and testosterone among schizophrenia patients in acute stage [0.03%]
急性期精神分裂症患者攻击行为和睾丸酮水平的关联性研究
Meng-Han Zhang,Jing Zhang,Hong Cai et al.
Meng-Han Zhang et al.
Testosterone play an important role in schizophrenia, particularly for impulsive aggressive behaviors. However, there is still unclear how the neurobiological basis and correlates of these risk factors in schizophrenia patients. The schizop...
Evaluating the PANSS using item response theory in forensic psychiatric samples from five European nations [0.03%]
五项欧洲国家的刑事精神病样本使用项目响应理论评估PANSS量表
Andreas Wippel,Giovanni de Girolamo,Pawel Gosek et al.
Andreas Wippel et al.
Item Response Theory (IRT) describes a set of statistical models describing how individual items in a test or questionnaire relate to the underlying characteristic or trait that the test claims to measure. Until now IRT models have not been...
Salience network segregation and symptom profiles in psychosis risk subgroups among youth and early adults [0.03%]
青壮年高精神病发病风险亚组的显著性网络分离及症状特征分析
Aditya Iyer,William Stanford,Eran Dayan et al.
Aditya Iyer et al.
Understanding neurobiological similarities among individuals with psychosis risk symptoms can improve early identification and intervention strategies. We aimed to (i) identify neurobiologically similar psychosis risk subgroups by integrati...
Eduard Parellada,Patricia Gassó
Eduard Parellada