Editors' Choice-Perspective-Deciphering the Glycan Kryptos by Solid-State Nanopore Single-Molecule Sensing: A Call for Integrated Advancements Across Glyco- and Nanopore Science [0.03%]
编者选择-透视-通过固态纳米孔单分子传感解读糖链密码：整合推进糖科学和纳米孔科学研究的号召
Megan E Kizer,Jason R Dwyer
Megan E Kizer
Glycans, or complex carbohydrates, are information-rich biopolymers critical to many biological processes and with considerable importance in pharmaceutical therapeutics. Our understanding, though, is limited compared to other biomolecules ...
Perspective-Advances in Voltammetric Methods for the Measurement of Biomolecules [0.03%]
展望——生物分子伏安法测量方法研究进展
Nadiah Alyamni,Jandro L Abot,Alexander G Zestos
Nadiah Alyamni
Voltammetry is a powerful electroanalytical tool that makes fast, real-time measurements of neurotransmitters and other molecules. Electroanalytical methods like cyclic, pulse, and stripping voltammetry are useful for qualitative and quanti...
Editors' Choice-Review-The Future of Carbon-Based Neurochemical Sensing: A Critical Perspective [0.03%]
主编选择-评论-碳基神经化学感应的未来：一个批判性观点
Blaise J Ostertag,Ashley E Ross
Blaise J Ostertag
Carbon-based sensors have remained critical materials for electrochemical detection of neurochemicals, rooted in their inherent biocompatibility and broad potential window. Real-time monitoring using fast-scan cyclic voltammetry has resulte...
Perspective-Assessing Electrochemical, Aptamer-Based Sensors for Dynamic Monitoring of Cellular Signaling [0.03%]
评估细胞信号动态监测的电化学适配体传感器
Celeste R Rousseau,Hope Kumakli,Ryan J White
Celeste R Rousseau
Electrochemical, aptamer-based (E-AB) sensors provide a generalizable strategy to quantitatively detect a variety of targets including small molecules and proteins. The key signaling attributes of E-AB sensors (sensitivity, selectivity, spe...
Screen-Printed Silver/Silver Chloride Electrodes Inhibit Alcohol Oxidase Activity [0.03%]
抑制酒石酸脱氢酶活性的屏打银/氯化银电极
Bob M Lansdorp,Peter Lamberg,Rashad Hamid
Bob M Lansdorp
Silver/silver chloride (Ag/AgCl) is ubiquitous in the field of electrochemical biosensing due to its suitability as a reference electrode material. However, we recently discovered that screen-printed Ag/AgCl ink has a detrimental effect on ...
Sara R Nixon,Imon Kanta Phukan,Brian J Armijo et al.
Sara R Nixon et al.
In proximity-driven sensing, interactions between a probe and an analyte produce a detectable signal by causing a change in distance of two probe components or signaling moieties. By interfacing such systems with DNA-based nanostructures, p...
Perspective-The Feasibility of Continuous Protein Monitoring in Interstitial Fluid [0.03%]
透视—间质液中蛋白质连续监测的可行性研究
Thomas Young,Vincent Clark,Netzahualcóyotl Arroyo-Currás et al.
Thomas Young et al.
Real-time continuous monitoring of proteins in-vivo holds great potential for personalized medical applications. Unfortunately, a prominent knowledge gap exists in the fundamental biology regarding protein transfer and correlation between i...
Expanding the Monolayer Scope for Nucleic Acid-Based Electrochemical Sensors Beyond Thiols on Gold: Alkylphosphonic Acids on ITO [0.03%]
基于核酸的电化学传感器的单层范围扩展：超越金上的硫族化合物，ITO上的烷基磷酸盐
Alexander Shaver,Netzahualcóyotl Arroyo-Currás
Alexander Shaver
Electrochemical biosensors are a powerful and rapidly evolving molecular monitoring technology. Evidenced by the success of the continuous glucose monitor in managing Type 1 Diabetes, these sensors are capable of precise, accurate measureme...
Julia Chung,Lior Sepunaru,Kevin W Plaxco
Julia Chung
Electrochemical aptamer-based (EAB) sensors encompass the only biosensor approach yet reported that is simultaneously: (1) independent of the chemical or enzymatic reactivity of its target, rendering it general; (2) continuous and real-time...
A Strategy for Accessing Nanobody-Based Electrochemical Sensors for Analyte Detection in Complex Media [0.03%]
用于复杂介质中分析物检测的纳米体基电化学生物传感器策略研究
Ruolan Fan,Yanfeng Li,Kwang-Won Park et al.
Ruolan Fan et al.
Nanobodies are single variable domain antibodies isolated from camelids and are rapidly distinguishing themselves as ideal recognition elements in biosensors due to their comparative stability, ease of production and isolation, and high bin...