CCR2- T peripheral helper cells as potential coordinators of local immune architecture in human cancer [0.03%]
人癌中的CCR2- T周细胞辅助型T细胞作为潜在的局部免疫结构协调者
Celia Del Carmen Crespo Oliva,Zoé Gerber,Dominique Jean et al.
Celia Del Carmen Crespo Oliva et al.
Introduction: Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, yet tumor progression remains a challenge, necessitating improved patient stratification and therapeutic strategies. Tumor growth rel...
Immunity to helminths in complex environments: co-infection disrupts effective granuloma formation and parasite clearance [0.03%]
肠道寄生线虫的免疫反应受共感染影响：共感染破坏有效的肉芽肿形成和寄生虫清除反应
Breton Fougere,Anupama Ariyaratne,Naomi Chege et al.
Breton Fougere et al.
Introduction: The intestinal roundworm Heligmosomoides bakeri establishes chronic infections in susceptible C57Bl/6 mice, yet repeated ('trickle') infections confer immunity and promote worm clearance. We previously linke...
Porcine influenza mAbs to H3, H5, and H7 hemagglutinins recognize H3 egg adapted site and target the HA stem [0.03%]
针对H3、H5和H7血凝素的猪源性流感单克隆抗体识别H3卵适应性位点并靶向血凝素茎部
Tiphaine Cayol,Sonia Villanueva-Hernández,Emily Briggs et al.
Tiphaine Cayol et al.
Introduction: Monoclonal antibodies (mAbs) are critical tools for elucidating viral evolution, informing vaccine design, and developing antiviral therapeutics. Large-animal models, such as the pig, that closely mirror hum...
Jacob A Cohen,Simon Hunter-Barnett,Gayathri Nageswaran et al.
Jacob A Cohen et al.
Introduction: Wild animals live in a pathogen-rich environment and are normally infected with a wide range of micro- and macro-parasites. Wild animals' T cells are central to the effectiveness of their adaptive immune res...
Large neutral amino acid uptake and mTOR activation within CD4 T cells coordinate type 2 immunity and host resistance to Trichuris muris [0.03%]
CD4 T细胞中的大中性氨基酸吸收和mTOR活化协调了2型免疫和宿主对Trichuris muris的抵抗力
Maria Z Krauss,Kelly S Hayes,Suzanne H Hodge et al.
Maria Z Krauss et al.
Introduction: Trichuris trichiura (whipworm) is a gastrointestinal nematode that infects approximately 465 million people worldwide. Trichuris muris is used as a tractable model for the human whipworm. In wild-type mice, ...
Correction to: Inflammation's impact on the interaction between oligodendrocytes and axons [0.03%]
炎症对少突胶质细胞和轴突相互作用的影响的更正通知
[This corrects the article DOI: 10.1093/discim/kyaf008.]. © The Author(s) 2026. Published by Oxford University Press on behalf of the British Society of...
Published Erratum
Discovery immunology. 2026 Mar 7;5(1):kyag005. DOI:10.1093/discim/kyag005 2026
Out of the shed and into the field: an immune toolkit for measuring wild ungulate immune phenotypes at multiple scales [0.03%]
走出棚舍，步入田野：一个免疫工具箱，在多个尺度上测量野生偶蹄动物的免疫表型
Luke Weinstein,Brian P Dolan,Holly K Arnold et al.
Luke Weinstein et al.
Introduction: Understanding factors that shape immune responses in wild animals is critical to predicting population resilience and long-term persistence. Immune function modifies the survival of individuals facing infect...
Striking a balance: how the gut microbiome shapes the fate of intestinal CD4+ T cells [0.03%]
求同存异：肠道菌群如何影响肠内CD4⁺T细胞的命运走向
Jessica M Till,Orion D Brock,Philip P Ahern
Jessica M Till
The induction of immune tolerance, a state of immunologic hyporesponsiveness to an antigen, is essential to prevent the destructive potential of the immune system in response to harmless or beneficial agents. Early efforts to understand tol...
Early disruption of the innate-adaptive immune axis in vivo after infection with virulent Georgia 2007/1 ASFV [0.03%]
高致病性格鲁吉亚2007/1毒株非洲猪瘟病毒感染后活体先天免疫和获得性免疫轴的早期破坏
Priscilla Y L Tng,Laila Al-Adwani,Lynnette Goatley et al.
Priscilla Y L Tng et al.
Effective immune defence and pathogen clearance requires coordination between innate and adaptive immune responses. However, virulent African swine fever virus (ASFV), which has a high case fatality rate in pigs, causes severe disease by ex...
Sam Bankole,Lai Guan Ng,Florent Ginhoux
Sam Bankole