Using peptide-exchange systems to interrogate peptide-specific KIR binding to HLA Class I [0.03%]
利用肽交换系统研究KIR与HLA-I类分子的肽特异性结合
Tanusya M Murali,Beining Li,Emery Hoos et al.
Tanusya M Murali et al.
Introduction: The killer-cell immunoglobulin-like receptors (KIR) are a family of activating and inhibitory Class I human leukocyte antigen (HLA-I) binding receptors expressed on natural killer (NK) cells and subsets of T...
Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific immune response after vaccination and challenge [0.03%]
猪B细胞受体重链组库特征分析表明疫苗接种和攻毒后广泛公共伪狂犬病毒特异性免疫反应的发展
Valentin Herbet,Edouard Hirchaud,Yannick Blanchard et al.
Valentin Herbet et al.
Introduction: The antibody repertoire reflects the immune history of an individual. In the present study, we characterized the porcine antibody heavy-chain repertoire following vaccination and challenge with pseudorabies ...
A pathogenic CD4 T cell phenotype in experimental uveitis shares common features with other immune mediated inflammatory diseases [0.03%]
实验性虹膜炎中的致病CD4 T细胞表型与其他自身免疫性疾病共有的特征
Amy Ward,Oliver H Bell,Luis Martinez-Robles et al.
Amy Ward et al.
Introduction: Murine ocular autoimmunity develops through three stages; prodrome, primary peak, and secondary regulation. During the prodromal phase, leukocytes accumulate within the retina and vitreous. ...
Functional responses of lymphoid stromal cells to Toll-like receptor stimuli in vitro [0.03%]
体外淋巴组织基质细胞对 toll 样受体刺激的功能反应
Isabella Cinti,Kassandra Vezyrgianni,Alice E Denton
Isabella Cinti
Introduction: Lymphoid stromal cells control the spatial organization of lymphoid tissues and respond dynamically during immune reactions, undergoing transcriptional and phenotypic changes that can influence immune respon...
CCR2- T peripheral helper cells as potential coordinators of local immune architecture in human cancer [0.03%]
人癌中的CCR2- T周细胞辅助型T细胞作为潜在的局部免疫结构协调者
Celia Del Carmen Crespo Oliva,Zoé Gerber,Dominique Jean et al.
Celia Del Carmen Crespo Oliva et al.
Introduction: Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, yet tumor progression remains a challenge, necessitating improved patient stratification and therapeutic strategies. Tumor growth rel...
Immunity to helminths in complex environments: co-infection disrupts effective granuloma formation and parasite clearance [0.03%]
肠道寄生线虫的免疫反应受共感染影响：共感染破坏有效的肉芽肿形成和寄生虫清除反应
Breton Fougere,Anupama Ariyaratne,Naomi Chege et al.
Breton Fougere et al.
Introduction: The intestinal roundworm Heligmosomoides bakeri establishes chronic infections in susceptible C57Bl/6 mice, yet repeated ('trickle') infections confer immunity and promote worm clearance. We previously linke...
Porcine influenza mAbs to H3, H5, and H7 hemagglutinins recognize H3 egg adapted site and target the HA stem [0.03%]
针对H3、H5和H7血凝素的猪源性流感单克隆抗体识别H3卵适应性位点并靶向血凝素茎部
Tiphaine Cayol,Sonia Villanueva-Hernández,Emily Briggs et al.
Tiphaine Cayol et al.
Introduction: Monoclonal antibodies (mAbs) are critical tools for elucidating viral evolution, informing vaccine design, and developing antiviral therapeutics. Large-animal models, such as the pig, that closely mirror hum...
Jacob A Cohen,Simon Hunter-Barnett,Gayathri Nageswaran et al.
Jacob A Cohen et al.
Introduction: Wild animals live in a pathogen-rich environment and are normally infected with a wide range of micro- and macro-parasites. Wild animals' T cells are central to the effectiveness of their adaptive immune res...
Large neutral amino acid uptake and mTOR activation within CD4 T cells coordinate type 2 immunity and host resistance to Trichuris muris [0.03%]
CD4 T细胞中的大中性氨基酸吸收和mTOR活化协调了2型免疫和宿主对Trichuris muris的抵抗力
Maria Z Krauss,Kelly S Hayes,Suzanne H Hodge et al.
Maria Z Krauss et al.
Introduction: Trichuris trichiura (whipworm) is a gastrointestinal nematode that infects approximately 465 million people worldwide. Trichuris muris is used as a tractable model for the human whipworm. In wild-type mice, ...
Correction to: Inflammation's impact on the interaction between oligodendrocytes and axons [0.03%]
炎症对少突胶质细胞和轴突相互作用的影响的更正通知
[This corrects the article DOI: 10.1093/discim/kyaf008.]. © The Author(s) 2026. Published by Oxford University Press on behalf of the British Society of...
Published Erratum
Discovery immunology. 2026 Mar 7;5(1):kyag005. DOI:10.1093/discim/kyag005 2026