The Indian Ocean Dipole drives imported-dominated dengue outbreaks in China: Mechanisms and predictions [0.03%]
印度洋偶极子驱动中国登革热输入性流行：机制和预测
Jian Ma,Lei Xu,Qian Han et al.
Jian Ma et al.
Dengue fever, influenced by climate dynamics and human mobility in nonendemic regions, remains poorly understood. We assessed the effects of large-scale climate features on domestic dengue outbreaks using data from China (2013-2021) and pro...
Chemical signaling in reaction networks generates corresponding mechanical impulses [0.03%]
化学信号在反应网络中产生相应的机械脉冲
Oleg E Shklyaev,Anna C Balazs
Oleg E Shklyaev
Chemical reaction networks (CRNs) in the body are directed pathways that transmit reagents to reactive sites and trigger chemical processes, which ultimately instigate the appropriate physical activity. Typically, models for CRNs do not des...
Roy H Perlis
Roy H Perlis
The National Institutes of Health (NIH) awards additional funds for extramural research to support research infrastructure and administration, such that the total cost of a given research project depends on where it is conducted. We sought ...
Molecular simulations meet personalized medicine: The mechanism of action of CLC-5 antiporter and the origin of Dent's disease [0.03%]
分子模拟与个性化医疗的结合：CLC-5反向转运蛋白的作用机制及Dent病的发病原因分析
Veronica Macaluso,Carles Pérez,Robert Soliva et al.
Veronica Macaluso et al.
ClC-5 is a Cl-/H+ antiporter crucial for the homeostasis of the entire organism, and whose functional deficiencies cause pathologies such as Dent's disease, a rare genetic disorder that can have lethal consequences. While the clinical aspec...
Andrew Kruczkiewicz,Zinta Zommers,Joyce Kimutai et al.
Andrew Kruczkiewicz et al.
The scientific community has produced increasingly robust knowledge and evidence of the physical impacts of warming on time scales of tens of decades and longer. However, the social and humanitarian impacts of climate overshoot remain large...
Post-January 6 deplatforming shows long-term effects on ideological polarization among Twitter users [0.03%]
1月6日事件后推特封禁的影响显示对用户有着长期的意识形态极化效应
Cody Buntain,Maria Snegovaya
Cody Buntain
This study examines audience response to Twitter's "Great Deplatforming" following the January 6 attack on the US Capitol. Using a survey of Twitter users from the 2020 US election, we test whether Twitter's deplatforming coincides with sig...
Discriminating abiotic and biotic organics in meteorite and terrestrial samples using machine learning on mass spectrometry data [0.03%]
基于质谱数据的机器学习鉴别陨石和地表样品中的非生物有机物和生物有机物
Daniel Saeedi,Denise Buckner,Thomas A Walton et al.
Daniel Saeedi et al.
With the upcoming sample return missions to the Solar System where traces of past, extinct, or present life may be found, there is an urgent need to develop unbiased methods that can distinguish molecular distributions of organic compounds ...
Community hydrodynamics created ecological opportunity in Ediacaran shallow marine ecosystems [0.03%]
群体水动力学在埃迪卡拉纪浅海生态系统中创造了生态机遇
Susana Gutarra,Emily G Mitchell,Rachel L Surprenant et al.
Susana Gutarra et al.
The "second wave" of Ediacaran evolution (∼558-548 Ma) was characterized by the appearance of macroscopic organisms in shallow marine settings, where they formed communities with high morphological and ecological diversity, including new a...
Automated pain assessment based on facial expression of free-moving mice [0.03%]
基于自由活动小鼠面部表情的自动化疼痛评估
Koji Kobayashi,Naoaki Sakamoto,Yusuke Miyazaki et al.
Koji Kobayashi et al.
Pain is a basic sensation associated with tissue injury. Although facial expression is a useful indicator of pain in mammals, its assessment in rodents requires expertise and experience. Here, we aimed to establish an automated pain assessm...
Single-cell mapping of the glycocalyx in the adult human and mouse ocular surface [0.03%]
成人人类和小鼠眼表糖萼的单细胞图谱测绘
Rafael Martínez-Carrasco,Pablo Argüeso
Rafael Martínez-Carrasco
The glycocalyx is a critical but often underappreciated modulator of cellular behavior. Its diversity across cell types within tissues remains poorly understood, but recent advances in single-cell profiling now enable more precise analysis ...