Life on the edge: Mesolithic population size and viability on Malta [0.03%]
边缘求生:马耳他_mesolithic时期的居住规模与生存状况
James Blinkhorn,Lucy Timbrell,Matt Grove et al.
James Blinkhorn et al.
Recent discoveries in Malta and Tunisia provocatively point to a possible web of Mesolithic/Epipalaeolithic sea crossings, encounters, and exchanges that linked continents long before the age of the sail. Determining whether such connection...
Nanotubes enable intercellular communication in early-branching eukaryotes [0.03%]
纳米管在早期真核生物支系间的细胞间通讯中的作用
Harikumar R Suma,Robert R Kay,Sandeep M Eswarappa et al.
Harikumar R Suma et al.
Social amoebae, despite being unicellular organisms, exhibit multicellular phenotypes that require well-tuned inter- and intracellular communication modes. The social amoeba Dictyostelium discoideum is an excellent model to study multicellu...
Reconciling the effects of PMS2 in different repeat expansion disease models supports a common expansion mechanism [0.03%]
PMS2在不同重复序列扩张疾病模型中的作用一致支持了一个共同的扩张机制
Carson J Miller,Diego Antonio Jimenez,Alexandra Walker et al.
Carson J Miller et al.
Expansion of a disease-specific tandem repeat is responsible for >45 repeat expansion diseases (REDs). The expansion mutation in each of these diseases has different pathological consequences, and most are currently incurable. If the underl...
Memorizing the future: Encoding anticipated interactions enhances human memory for dynamic stimuli [0.03%]
预想促进记忆:预想的互动增强人类对动态刺激的记忆编码
Gonzalo Aparicio-Rodríguez,Daniel Ruiz Navalón,Paloma Manubens et al.
Gonzalo Aparicio-Rodríguez et al.
Survival in nature requires responding to rapidly changing situations, where memory is crucial for fast and reliable decision-making. This work explores human memory modulation under the hypothesis that in dynamic scenarios critical informa...
Reduced integrity in the frontal aslant tract's premotor connections is associated with dysfluency severity in stuttering [0.03%]
有关口吃流畅度严重程度的降低与前部运动传导束连接完整性降低相关性研究
Maëva Michon,Fabrice Hirsch,Ivana Didirková et al.
Maëva Michon et al.
Stuttering is a neurodevelopmental disorder marked by impaired speech production and substantial interindividual variability in symptom severity. Although neuroimaging studies have identified abnormalities in the basal ganglia-thalamocortic...
Functional role of a structural water in the elevator domain of dicarboxylate transporter VcINDY [0.03%]
电梯域中结构水在二羧酸转运蛋白VcINDY中的功能作用
Andrew Daab,Yan Li,Jennifer J Marden et al.
Andrew Daab et al.
The divalent anion sodium symporter (DASS) family mediates the uptake of Krebs cycle intermediates and sulfate and influences adiposity, insulin resistance, and metabolism in mammals. While Na+:substrate stoichiometry is known for several D...
Tipping points in urban growth: How urbanization reshapes flood resilience and social vulnerability in China [0.03%]
中国城市化进程中人口和社会脆弱性的转变对洪水韧性的影响研究
Xiguang Liu,Yue Wu,Rui Ren et al.
Xiguang Liu et al.
Urbanization is often portrayed as either a pathway to progress or a process that could amplify disaster risk. Yet, its true influence lies in how it reshapes resilience to hazards and the vulnerability of people most at risk. Using provinc...
Six misconceptions about large language models: A minimal model and diagnostic taxonomy [0.03%]
关于大型语言模型的六大误解:最小模型与诊断分类学
Zhicheng Lin
Zhicheng Lin
Large language models (LLMs) are now embedded in scientific, educational, and governance workflows, with debates centering on their capabilities, mechanisms, and impacts. Yet these debates remain structured by persistent folk theories-intui...
Ankyrin-B and ankyrin-G are required for synaptic integrity in the mouse outer retina [0.03%]
Ankiran-B和Ankirin-G是小鼠外视网膜突触完整性所需要的
Ross M Perez,Jay Campbell,Martina Cavallini et al.
Ross M Perez et al.
Retinal circuit assembly relies on the precise timing and positioning of key molecules between neuronal partners to mediate proper synapse formation. In the outer retina, horizontal cells (HCs) are important interneurons that make the first...
Machine learning as an interpretive consistency approach for coupling geochemical and geophysical domains in data-limited landfills [0.03%]
机器学习作为一种解释一致性方法,在数据受限条件下的 landfill 地化和地物理域的耦合中的应用研究
Vincenzo Costanzo-Álvarez,Maria Jácome,Milagrosa Aldana et al.
Vincenzo Costanzo-Álvarez et al.
Understanding landfill-related groundwater contamination is challenging in heterogeneous hydrogeological settings characterized by sparse monitoring networks and limited subsurface information, constraints common to many environmental and e...