The microtubule nexus linking amyloid beta and tau: A simple and unifying theory for the underlying cause of Alzheimer's disease [0.03%]
Thomas A Shoff,Maxence Derbez-Morin,Peishan Cai et al.
Thomas A Shoff et al.
Alzheimer's disease (AD) is defined by cognitive decline in conjunction with accumulation of aggregated amyloid β (Aβ) and tau, yet existing models of AD fail to provide a simple connection between Aβ and tau. However, microtubules provi...
Entrepreneurs of conflict: A descriptive analysis of when and how political elites use divisive rhetoric [0.03%]
Marc S Jacob,Yphtach Lelkes,Sean J Westwood
Marc S Jacob
The rise of divisive rhetoric in American politics reflects and reinforces broader system-level polarization, yet the incentives driving this behavior are not well understood. To investigate this puzzle, we conduct a large-scale descriptive...
Discovering and protecting cryptic biodiversity: A case study of a previously undescribed, vulnerable bird species in Japan [0.03%]
Takema Saitoh,Daria Shipilina,Canwei Xia et al.
Takema Saitoh et al.
Despite the escalating biodiversity crisis, many species remain unknown to science and may even disappear unnoticed. This is particularly true for many island populations. We illustrate the problem of detecting overlooked species and its co...
From local production to global consumption: Assessing the carbon footprints of Chinese cities in global value chains [0.03%]
从本地生产到全球消费：评估中国城市在全球价值链中的碳足迹
Shaojian Wang,Junyi Liang,Yuli Shan et al.
Shaojian Wang et al.
As cities take on increasingly specialized roles in global value chains (GVCs), the spatial disconnect between where emissions occur and where responsibility lies continues to widen. However, city-level carbon flows across GVCs remain large...
What does a good day look like?: An interpretable machine learning approach to the American Time Use Survey [0.03%]
美好的一天是什么样的？美国时间使用调查的可解释机器学习方法研究
Dunigan Folk,Mirka Henninger,Elizabeth Dunn
Dunigan Folk
What differentiates a happy day from a typical one? Using interpretable machine learning techniques, we assessed the relationship between the time people spent on over 100 activities and whether they rated their day as typical or "better th...
Spatially resolved multiplex protein profiling reveals DNA methylation-dependent microenvironmental remodeling in liver fibrosis [0.03%]
空间分辨的多重蛋白质谱分析揭示肝纤维化中DNA甲基化依赖性的微环境重塑现象
Jiaxun Li,Nicholas Zhang,Sriya Sirigireddy et al.
Jiaxun Li et al.
Liver fibrosis is a significant health concern that affects ∼300 million people globally, characterized by the excessive accumulation of extracellular matrix (ECM) components in the liver. A major contributor to liver fibrosis is fatty liv...
Significant benefits of pollution alerts for cleaner air and better health [0.03%]
污染警告对改善空气质量和健康的好处显著
Yuqing Dai,Juncheng Qian,Yue Yang et al.
Yuqing Dai et al.
While air quality has improved in many cities, short-term spikes in urban pollution continue to cause elevated health risks. To mitigate such risks, pollution alerts trigger short-term interventions (e.g. temporary industrial curtailments o...
Toward a science of human-AI teaming for decision making: A complementarity framework [0.03%]
迈向决策中的人工智能协作的科学：互补性框架
Cleotilde Gonzalez,Kate Donahue,Daniel G Goldstein et al.
Cleotilde Gonzalez et al.
As artificial intelligence (AI) becomes embedded in critical decisions involving health, safety, finance, and governance, the key challenge is no longer whether humans and AI will collaborate, but rather how to structure this collaboration ...
Atlas of intracranial electroencephalography complexity across cortical regions and global states of consciousness in the human brain [0.03%]
人脑皮层各区和整体意识状态的颅内脑电复杂性图谱
Lina Jeantin,Pierre Bourdillon,Marc Guenot et al.
Lina Jeantin et al.
Electroencephalography (EEG) signal complexity reflects the richness of brain activity and is considered a marker of consciousness. However, its normative values across physiological conscious states using intracranial EEG (iEEG) across cor...
Gender and culture shape prosociality more than heat stress in a five-country experiment [0.03%]
一项五国实验表明，性别和文化比热应力更能影响利他行为
Alessandra Cassar,Andrew Hobbs,Jesse Anttila-Hughes et al.
Alessandra Cassar et al.
A consistent finding regarding human societies is that higher temperatures lead to antisocial behavior, including more crime, violence, aggression, and civil conflict. A large body of research documents this relationship at the societal lev...