Estriol attenuates visceral adiposity and pulmonary artery smooth muscle cell proliferation via ERα-mediated signalling [0.03%]
雌三醇通过雌激素受体α介导的信号减轻内脏脂肪和肺动脉平滑肌细胞增殖
Smriti Sharma,Joshua P Dignam,Gregor Aitchison et al.
Smriti Sharma et al.
Aims: Estriol (E3) is a natural estrogen produced during pregnancy whose physiological role in the adult cardiovascular and pulmonary systems remains poorly understood. Given the established association between estrogens ...
Bioprosthetic vs. mechanical prostheses in patients aged 50-70 years undergoing aortic valve replacement surgery: outcomes analysis from propensity score matching [0.03%]
生物瓣膜与机械瓣膜在主动脉瓣置换术中用于50-70岁患者的临床效果：来自倾向性匹配的分析结果
William A Courtney,Primero Ng,Charley Budgeon et al.
William A Courtney et al.
Aims: Bioprosthetic valves are increasingly used for surgical aortic valve replacement (SAVR) in patients ≤ 70 years though the relative benefits compared to mechanical valve replacement remain uncertain. This study aims...
Advanced electronic consultation between primary care and cardiology: impact of tele-echocardiography and event-based electrocardiographic monitoring [0.03%]
基层医疗与心脏病学之间的高级电子咨询：远程心脏超声和基于事件的心电监测的影响
Juan José Augusto Sánchez Castro,Alejandro Virgos Lamela,Daniel Rey Aldana et al.
Juan José Augusto Sánchez Castro et al.
Electronic consultation (econsultation) has proven effective in optimizing communication between primary care and cardiology, reducing waiting times and unnecessary face-to-face referrals. This study assessed the impact of incorporating tel...
Sex-specific differences in cardiac transthyretin amyloidosis: addressing the diagnostic gap in women [0.03%]
性别特异性的卡氏甲状腺转运蛋白淀粉样变心肌病的诊断差异：解决女性患者中的诊断差距问题
Julia Vogel,Sophia Jura,Stephan Settelmeier et al.
Julia Vogel et al.
Aims: Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed cause of heart failure. With a male:female ratio of approximately 10:1, current evidence including diagnostic criteria is largely based on male-dom...
Impact of foetal growth restriction and being born small for gestational age on newborn echo- and electrocardiographic measurements-a Copenhagen baby heart study [0.03%]
胎儿生长受限和宫内生长受限对新生儿心电图和心脏超声检查的影响——来自哥本哈根婴儿心脏研究的数据
Emil H Nørskov,Signe L Skjellerup,Johan E Navne et al.
Emil H Nørskov et al.
Aims: Foetal growth restriction (FGR) and being born small for gestational age (SGA) have been linked to later cardiovascular disease. We examined the impact of FGR and SGA on neonatal echo- and electrocardiographic measu...
Sustained HIF activation in adult cardiomyocytes show transient beneficial effect in murine HFpEF model [0.03%]
缺氧诱导因子活化在成年心肌细胞中的持续作用可对小鼠HFpEF模型产生短暂的有益效果
Daigo Sawaki,Takayuki Isagawa,Shigeru Sato et al.
Daigo Sawaki et al.
Aims: Hypoxia-inducible factor (HIF) signalling influences cardiomyocyte differentiation, maturation, and metabolic adaptation under pathological conditions. HIF-Prolyl hydroxylase domain (HIF-PH) inhibitors, which target...
The effect of cardiac resynchronization therapy on functional capacity based on cardiopulmonary exercise testing: a systematic review and meta-analysis [0.03%]
基于心肺运动试验的心脏再同步治疗对功能容量影响的系统评价和 meta 分析
Jhiamluka Solano,Nithusa Rahunathan,Dominic L Sykes et al.
Jhiamluka Solano et al.
Aims: Cardiac resynchronization therapy (CRT) has a class 1a indication for patients with heart failure due to reduced ejection fraction (HFrEF) who also have conduction delay. Post-CRT management pathways are uncommon. C...
Relationship of cancer and dual antiplatelet duration to long-term risk of ischaemic and bleeding outcomes after percutaneous coronary intervention [0.03%]
冠心病经皮冠状动脉介入术后癌症与双重抗血小板疗程对缺血和出血长期风险的影响关系研究
Ramael Ohiomoba,Edwin Mandieka,Melissa M Young et al.
Ramael Ohiomoba et al.
Aims: The long-term cardiovascular (CV) risks after percutaneous coronary intervention (PCI) in cancer patients are unclear. We assessed the risks of adverse events after PCI related to active or inactive cancer and the d...
Pulmonary arterial hypertension after congenital heart defect correction: a call for timely diagnosis and careful risk stratification to improve outcomes [0.03%]
先天性心脏病术后发生肺动脉高压：及时诊断和仔细评估风险以改善预后不容忽视
Qiangqiang Li,Yuan He,Andrew Constantine et al.
Qiangqiang Li et al.
Aims: Patients with pulmonary arterial hypertension (PAH) after congenital heart disease (CHD) correction (PAH-CHDcor) are becoming the most prevalent and rapidly expanding group within PAH associated with CHD (PAH-CHD), ...
Electronic nudges to increase influenza vaccination uptake in younger and middle-aged individuals with atrial fibrillation: a prespecified analysis of the NUDGE-FLU-CHRONIC trial [0.03%]
针对房颤患者增加流感疫苗接种率的电子干预措施：NUDGLE-FLU-CHRONIC试验的一项预设分析
Caroline Espersen,Niklas Dyrby Johansen,Muthiah Vaduganathan et al.
Caroline Espersen et al.
Aims: Little is known regarding strategies to improve influenza vaccination uptake among individuals with atrial fibrillation (AF). We assessed the effect of electronically delivered behavioural nudges on influenza vaccin...