Protective low-avidity anti-tumour CD8+ T cells are selectively attenuated by regulatory T cells [0.03%]
调节性T细胞选择性地抑制具有保护作用的低亲和力抗肿瘤CD8+t细胞
Gessa Sugiyarto,David Prossor,Osman Dadas et al.
Gessa Sugiyarto et al.
Objectives: Regulatory T cells (Treg) play a major role in the suppression of protective anti-tumour T cell responses. In the CT26 BALB/c murine model of colorectal carcinoma, Tregs differentially suppress responses to tw...