Selection and characterization of a DNA aptamer for Patulin and its application in a label-free fluorescence assay for fruit juices [0.03%]
用于水果汁中原茋检测的DNA适配体筛选及表征及其在无标记荧光分析中的应用
Sihan Wang,Jiayi Liang,Haiyang Jiang et al.
Sihan Wang et al.
Patulin (PTL, 154 Da) is a small molecule toxin produced as a mold metabolite. PTL is unstable in animals and is quickly converted to its metabolites. Thus, few successful antibodies were reported even after extensive efforts in hapten desi...
Arginine as host directed therapy in tuberculosis: insights from modulating arginine metabolism by supplementation and arginase inhibition [0.03%]
精氨酸作为结核病的宿主定向疗法：通过补充和鸟氨酸脱氨酶抑制来调节精氨酸代谢的见解
Qingkui Jiang,Ranjeet Kumar,Yi Zhao et al.
Qingkui Jiang et al.
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a global health challenge. Arginine metabolism is central to immune responses, regulating nitric oxide (NO) production via inducible NO synthase (Nos2) and competing pat...
Introducing One Health Advances: a new journal connecting the dots for global health [0.03%]
《一-health advances》——促进全球卫生问题的多学科合作的新期刊
Jianzhong Shen,Stefan Schwarz
Jianzhong Shen
An RBD bispecific antibody effectively neutralizes a SARS-CoV-2 Omicron variant [0.03%]
一种RBD双特异性抗体有效中和新冠病毒奥密克戎变异株
Mengqi Yuan,Yanzhi Zhu,Guanlan Liu et al.
Mengqi Yuan et al.
Potent neutralizing antibodies (nAbs) against SARS-CoV-2 are a promising therapeutic against the ongoing COVID-19 pandemic. However, the continuous emergence of neutralizing antibody escape variants makes it challenging for antibody therape...
Mink infection with influenza A viruses: an ignored intermediate host? [0.03%]
病毒的中间宿主可能会被忽视吗？——养殖水貂感染甲型流感病毒案例报告研究
Chris Ka Pun Mok,Kun Qin
Chris Ka Pun Mok
Continuously emergence of human infection with avian influenza A virus poses persistent threat to public health, as illustrated in zoonotic H5N1/6 and H7N9 infections. The recent surge of infection to farmed mink by multiple subtypes of avi...
A comparative study of intestinal Pseudomonas aeruginosa in healthy individuals and ICU inpatients [0.03%]
健康人和ICU住院患者肠道铜绿假单胞菌的比较研究
Yanyan Hu,Siheng Wang,Yanyan Zhang et al.
Yanyan Hu et al.
The human intestinal tract is considered the most important reservoir of the opportunistic pathogens, including Pseudomonas aeruginosa, which is often overlooked but critical due to its antimicrobial resistance and virulence. Public health ...
A novel strategy to attenuate porcine reproductive and respiratory syndrome virus by inhibiting viral replication in the target pulmonary alveolar macrophages via hematopoietic-specific miR-142 [0.03%]
通过造血特异性miR-142抑制靶细胞肺泡巨噬细胞内病毒复制从而减弱猪繁殖与呼吸综合症病毒的新策略研究
Shaoyuan Tan,Weixin Wu,Xinna Ge et al.
Shaoyuan Tan et al.
Porcine reproductive and respiratory syndrome virus (PRRSV) is an economically important pathogen for the global pork industry. Although modified live virus (MLV) vaccines are commonly used for PRRSV prevention and control, they still carry...