Maria Clarke,Charlotte K Hind,Philip M Ferguson et al.
Maria Clarke et al.
Some antimicrobial peptides (AMPs) have potent bactericidal activity and are being considered as potential alternatives to classical antibiotics. In response to an infection, such AMPs are often produced in animals alongside other peptides ...
A large screen identifies beta-lactam antibiotics which can be repurposed to target the syphilis agent [0.03%]
一块大型屏幕识别出可以被重新用于靶向梅毒病原体的β-内酰胺类抗生素
Kathryn A Hayes,Jules M Dressler,Steven J Norris et al.
Kathryn A Hayes et al.
Syphilis, caused by the spirochete Treponema pallidum subsp. pallidum (hereafter called T. pallidum), is re-emerging as a worldwide sexually transmitted infection. A single intramuscular dose of benzathine penicillin G is the preferred syph...
Going to extremes: progress in exploring new environments for novel antibiotics [0.03%]
极端求索：抗生素新作用环境研究进展
The discoveries of penicillin and streptomycin were pivotal for infection control with the knowledge subsequently being used to enable the discovery of many other antibiotics currently used in clinical practice. These valuable compounds are...
Targeting Acinetobacter baumannii resistance-nodulation-division efflux pump transcriptional regulators to combat antimicrobial resistance [0.03%]
靶向不动杆菌baumannii抗性结节分裂型外排泵转录调节物以对抗抗菌药物耐药性
Regulatory elements controlling gene expression fine-tune bacterial responses to environmental cues, including antimicrobials, to optimize survival. Acinetobacter baumannii, a pathogen notorious for antimicrobial resistance, relies on effic...