Aram F Swinkels,Egil A J Fischer,Lisa Korving et al.
Aram F Swinkels et al.
Fluoroquinolone resistance in E. coli isolates from livestock in Europe remains high despite EMA restrictions on fluoroquinolone use in animals. However, flumequine, a quinolone not classified as a fluoroquinolone by various regulatory bodi...
Regulation of erm(T) MLSB phenotype expression in the emergent emm92 type group A Streptococcus [0.03%]
新型emm92型A群链球菌中erm（T）MLS B表型表达的调节机制研究
Lillie M Powell,Soo Jeon Choi,Megan E Grund et al.
Lillie M Powell et al.
In the last decade, invasive group A Streptococcus (iGAS) infections have doubled in the US, with equivalent increases in MLSB (macrolide, lincosamide, and streptogramin B)-resistance. The emm92-type isolates carrying the erm(T) gene have b...
Highly drug resistant clone of Salmonella Kentucky ST198 in clinical infections and poultry in Zimbabwe [0.03%]
赞比亚由多重耐药的血清型Kentucky肠炎沙门氏菌ST198引起临床感染和家禽中流行
Tapfumanei Mashe,Gaetan Thilliez,Blessmore V Chaibva et al.
Tapfumanei Mashe et al.
A highly multidrug-resistant strain of Salmonella enterica serotype Kentucky (S. Kentucky) of sequence type (ST)198 emerged in North Africa and has since spread widely. To investigate the genetic diversity and phylogenetic relationship of S...
Challenges and applications of artificial intelligence in infectious diseases and antimicrobial resistance [0.03%]
人工智能在传染病和抗菌素耐药性方面的挑战与应用
Angela Cesaro,Samuel C Hoffman,Payel Das et al.
Angela Cesaro et al.
Artificial intelligence (AI) has transformed infectious disease control, enhancing rapid diagnosis and antibiotic discovery. While conventional tests delay diagnosis, AI-driven methods like machine learning and deep learning assist in patho...
Tackling the outer membrane: facilitating compound entry into Gram-negative bacterial pathogens [0.03%]
突破外膜：促进化合物进入革兰氏阴性细菌病原体
Deepanshi Saxena,Rahul Maitra,Rakhi Bormon et al.
Deepanshi Saxena et al.
Emerging resistance to all available antibiotics highlights the need to develop new antibiotics with novel mechanisms of action. Most of the currently used antibiotics target Gram-positive bacteria while Gram-negative bacteria easily bypass...
Kalinga Pavan T Silva,Anupama Khare
Kalinga Pavan T Silva
Apart from horizontal gene transfer and sequence-altering mutational events, antibiotic resistance can emerge due to the formation of tandem repeats of genomic regions. This phenomenon, also known as gene amplification, has been implicated ...
Limitations of current techniques in clinical antimicrobial resistance diagnosis: examples and future prospects [0.03%]
临床抗菌药物耐药诊断技术的现状及未来展望：实例与分析
Jack Hassall,Carmen Coxon,Vishal C Patel et al.
Jack Hassall et al.
Antimicrobial resistance is a global threat to public health. Without proactive intervention, common infections may become untreatable, restricting the types of clinical intervention that can be undertaken and reversing improvements in mort...
Examining the role of Acinetobacter baumannii plasmid types in disseminating antimicrobial resistance [0.03%]
阿氏不动杆菌质粒类型在播散抗菌素耐药性中作用的研究
Margaret M C Lam,Mehrad Hamidian
Margaret M C Lam
Acinetobacter baumannii is a Gram-negative pathogen responsible for hospital-acquired infections with high levels of antimicrobial resistance (AMR). The spread of multidrug-resistant A. baumannii strains has become a global concern. Spread ...
How do Gram-negative bacteria escape predation by Bdellovibrio bacteriovorus? [0.03%]
束球菌如何逃避芽孢杆菌的捕食？
Sourav Kumar Das,David Negus
Sourav Kumar Das
Bdellovibrio bacteriovorus is a small predatory bacterium which reproduces by invading and killing Gram-negative bacteria. The natural antimicrobial activity of B. bacteriovorus has garnered interest for the potential to develop this predat...
Antibiotic susceptibility testing using minimum inhibitory concentration (MIC) assays [0.03%]
最低抑菌濃度(MIC)試驗的抗生素耐藥性測試
Nikol Kadeřábková,Ayesha J S Mahmood,Despoina A I Mavridou
Nikol Kadeřábková
Antimicrobial resistance is due to genetic changes that allow bacteria to evade antibiotic treatment. Antimicrobial susceptibility testing is critical for the detection of antibiotic-resistant strains, the selection of effective therapeutic...