Connor D Flynn,Dingran Chang,Alam Mahmud et al.
Connor D Flynn et al.
Body-based biomolecular sensing systems, including wearable, implantable and consumable sensors allow comprehensive health-related monitoring. Glucose sensors have long dominated wearable bioanalysis applications owing to their robust conti...
From science to business: translating live biotherapeutic products to the clinic [0.03%]
从科学研究到商业应用：将活生物治疗产品引入临床领域
Maria Lluch-Senar
Maria Lluch-Senar
At Pulmobiotics, we engineer bacteria for the treatment of respiratory diseases. Here, we outline how we designed MycoChassis - an attenuated bacterium strain obtained by genome engineering of Mycoplasma pneumoniae (a human lung pathogen) -...
Yifan Dai,Lingchong You,Ashutosh Chilkoti
Yifan Dai
The concept of phase-separation-mediated formation of biomolecular condensates provides a new framework to understand cellular organization and cooperativity-dependent cellular functions. With growing understanding of how biological systems...
Lukas Eidenberger,Benjamin Kogelmann,Herta Steinkellner
Lukas Eidenberger
Plants can be engineered to recombinantly produce high-quality proteins such as therapeutic proteins and vaccines, also known as molecular farming. Molecular farming can be established in various settings with minimal cold-chain requirement...
Jie Wu,Hong Liu,Weiwei Chen et al.
Jie Wu et al.
Electrochemical biosensors incorporate a recognition element and an electronic transducer for the highly sensitive detection of analytes in body fluids. Importantly, they can provide rapid readouts and they can be integrated into portable, ...
Michael R Blatchley,Kristi S Anseth
Michael R Blatchley
Organoids recapitulate many aspects of the complex three-dimensional (3D) organization found within native tissues and even display tissue and organ-level functionality. Traditional approaches to organoid culture have largely employed a top...
Nicolas Rouleau,Nirosha J Murugan,David L Kaplan
Nicolas Rouleau
The functional complexity of the central nervous system (CNS) is unparalleled in living organisms. Its nested cells, circuits and networks encode memories, move bodies and generate experiences. Neural tissues can be engineered to assemble m...
Zhen Huang,Christopher J Lyon,Tony Y Hu
Zhen Huang
CRISPR-based assays can be adopted as ultrasensitive molecular diagnostics in resource-limited settings, but point-of-care applications must address additional requirements. Here, we discuss the major obstacles for developing these assays a...
Mario Urso,Martina Ussia,Martin Pumera
Mario Urso
Less than 1% of Earth's freshwater reserves is accessible. Industrialization, population growth and climate change are further exacerbating clean water shortage. Current water-remediation treatments fail to remove most pollutants completely...
Manu Platt talks about the new NIH Center for Biomedical Engineering Technology Acceleration [0.03%]
曼纽·普拉特谈NIH生物医学工程技术加速中心的新动态
Christine Horejs
Christine Horejs
The National Institute of Biomedical Imaging and Bioengineering has established a new Center for Biomedical Engineering Technology Acceleration, dedicated to applying engineering principles to biomedical discovery and therapeutics. We talk ...