Ameya P Chaudhari,Omar M Budayr,Emily E Bonacquisti et al.
Ameya P Chaudhari et al.
With their natural origin and biological compatibility, extracellular vesicles (EVs) are being recognized as next-generation vehicles for targeted drug delivery. Over the last two decades, the field of EV-based drug delivery has witnessed a...
Alessandro De Giorgi,Zhenwu Wang,Qing Li et al.
Alessandro De Giorgi et al.
Bioprinting technologies often require repeated experimental trials to optimize operational parameters and characterize bioprinted constructs. In this context, computational simulations have emerged as a powerful complementary tool, enablin...
Santosh R Rananaware,Karthik V Narisetty,Rushi A Shah et al.
Santosh R Rananaware et al.
Donor organs are frequently discarded because of concerns about quality or pathogen risk, challenges that could be mitigated through ex vivo gene editing or silencing during machine perfusion. Here, we discuss the development of CRISPR-base...
Jessica L Stelzel,Jonathan P Schneck,Hai-Quan Mao et al.
Jessica L Stelzel et al.
Immune responses are complex, often defying rigid classifications. Instead of interpreting results according to reductionist categories, researchers should rely on comprehensive single-cell data to guide analysis and should remain open to u...
Runxin Wu,Guinevere Ferreira,Nusrat Sadia Khan et al.
Runxin Wu et al.
Digital models and digital twins of human circulatory transport could transform the way cardiovascular and haematological diseases are understood, monitored and treated. Digital twins are dynamic virtual representations of physical systems ...
Favour Nerrise,Narayan Schütz,Qingyu Zhao et al.
Favour Nerrise et al.
Digital biomarkers (DBMs) are a new class of health indicators derived from digital technologies - including smartphones, wearable devices and ambient sensors - that enable continuous, real-time monitoring of signals in everyday settings. B...
Chanwoo Kim,Soham U Gadgil,Su-In Lee
Chanwoo Kim
Artificial intelligence (AI) systems are now prevalent in our daily lives and hold promise for transforming high-stakes fields such as healthcare. Medical AI systems are showing significant potential to support diagnostics and treatment rec...
Mechanomedicine [0.03%]
医工学
Zeyang Liu,Guorui Chen,Min-Seung Jo et al.
Zeyang Liu et al.
Mechanical forces act throughout the body across multiple scales, from organs and tissues to cells and molecules, playing a vital role in maintaining tissue integrity, regulating cellular functions and supporting physiological performance. ...
Junyi Yin,Shaolei Wang,Trinny Tat et al.
Junyi Yin et al.
Soft bioelectronic devices can be interfaced with anatomically curved organs, such as the heart, brain and skin, to provide continuous analysis of physiological information. However, body movements and physiological activities may induce mo...
Katherine O&#x;Connor,Paige Steppe,Daniel Worthley et al.
Katherine O&#x;Connor et al.
Living bacteria can serve as biosensors for the detection of DNA in vitro and in vivo, capitalizing on their inherent ability to take up and process foreign DNA. Such bactosensors can be engineered to analyze environmental DNA, down to the ...