Andrea Tavosanis
Andrea Tavosanis
Published Erratum
Nature cardiovascular research. 2026 May 11. DOI:10.1038/s44161-026-00825-3 2026
High-resolution cardiac mapping meets computational imaging to merge structure and function [0.03%]
高分辨率心脏标测与计算成像融合解剖和功能
Bastiaan J Boukens,Daniël A Pijnappels
Bastiaan J Boukens
Andrea Tavosanis
Andrea Tavosanis
Maarten M G van den Hoogenhof,Javier Duran,Thiago Britto-Borges et al.
Maarten M G van den Hoogenhof et al.
Although heart disease arises from different etiologies, treatment remains largely one-size-fits-all, leaving many patients without optimal benefit, which highlights the need for cause-directed therapies. Pathogenic variants in RBM20, a car...
Mechanisms and therapeutic potential of colchicine in atherosclerotic cardiovascular disease [0.03%]
秋水仙碱在动脉粥样硬化性心血管疾病中的机制和治疗潜力
Xinyi Xia,Fen Yang,Yuhan Liao et al.
Xinyi Xia et al.
Over the past decade, colchicine has re-emerged as a promising therapeutic candidate for atherosclerotic cardiovascular disease. Here we review evidence from large randomized controlled trials together with advances in mechanistic research ...
Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation [0.03%]
特异于TREM2+心脏巨噬细胞的抑癌基因Spp1干扰可抑制房颤发生发展
Noor Momin,Steffen Pabel,Arnab Rudra et al.
Noor Momin et al.
Atrial fibrillation and the risk of its lethal complications are propelled by fibrosis, which induces electrical heterogeneity and gives rise to reentry circuits. Atrial TREM2+ macrophages secrete osteopontin (encoded by Spp1), a matricellu...
PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathy [0.03%]
PCBP1通过调控AARS2的可变剪接影响先天性心肌病发病机制
Yao Wei Lu,Zhuomin Liang,Kerry Dorr et al.
Yao Wei Lu et al.
Mutations in the AARS2 gene are linked to infantile cardiomyopathy; however, the underlying molecular mechanism remains unknown. Here we report that PCBP1, a poly(rC) binding protein, interacts with the AARS2 transcript to mediate its alter...
Rachel L DeLancey,Sunil K Verma,Muge N Kuyumcu-Martinez
Rachel L DeLancey